!!Lauri Aaltonen - Selected Publications
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3. Aaltonen LA, Peltomäki P, Leach F, Sistonen P, Pylkkänen L, Mecklin J-P, Järvinen H, Powell S, Jen J, Hamilton S, Petersen G, Kinzler K, Vogelstein B & de la Chapelle A: Clues to the pathogenesis of familial colorectal cancer. Science 260, 812-816, 1993. 
IF 56.9. Times cited 2,599.\\
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28. Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Höglund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A & Aaltonen LA. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391, 184-187, 1998. IF 64.8. Times cited 1,191.\\
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30. Aaltonen LA, Salovaara R, Kristo P, Canzian F, Hemminki A, Peltomäki P, Chadwick RB, Percesepe A, Kääriäinen H, Ahtola H, Eskelinen M, Härkönen N, Julkunen R, Kangas E, Ojala S, Tulikoura J, Valkamo E, Järvinen H, Mecklin J-P & de la Chapelle A. Incidence of hereditary nonpolyposis colorectal cancer, and molecular screening for the disease. New England Journal of Medicine 338, 1481-1487, 1998. IF 158.5. Times cited 891.\\
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32. Howe JR, Roth S, Ringold JC, Summers RW, Järvinen HJ, Sistonen P, Tomlinson IPM, Houlston RS, Bevan S, Mitros FA, Stone EM & Aaltonen LA. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 280, 1086-1088, 1998. IF 56.9. Times cited 684.\\
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78. Tomlinson IPM, Alam NA, Rowan AJ, Barclay E, Kelsell D, Leigh I, Gorman P, Lamlum H, Rahman S, Roylance RR & Olpin S - Bevan S, Barker K, Hearle N & Houlston RS – Kiuru M, Lehtonen R, Karhu A, Vilkki S, Laiho P, Eklund C, Vierimaa O, Aittomäki K, Hietala M, Sistonen P, Paetau A, Salovaara R, Herva R, Launonen V & Aaltonen LA. Germline mutations in the fumarate hydratase gene predispose to dominantly inherited uterine fibroids, skin leiomyomata and renal cell cancer. Nature Genetics 30, 406-410, 2002. \\
IF 30.8. Times cited 1,116.\\
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135. Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen K, Ebeling TML, Salmela PI, Paschke R, Gündogdu S, de Menis E, Mäkinen M, Launonen V, Karhu A & Aaltonen LA. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 312, 1228-1230, 2006. IF 56.9. Times cited 419.\\
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213. Mäkinen N, Mehine M, Tolvanen J, Kaasinen E, Li Y, Lehtonen HJ, Gentile M, Yan J, Enge M, Taipale M, Aavikko M, Katainen R, Virolainen E, Böhling T, Koski TA, Launonen V, Sjöberg J, Taipale J, Vahteristo P & Aaltonen LA. MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas. Science 334, 252-255, 2011. IF 56.9. Times cited 442.\\
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237. Mehine M, Kaasinen E, Mäkinen N, Katainen R, Kämpjärvi K, Pitkänen E, Heinonen H-R, Bützow R, Kilpivaara O, Kuosmanen A, Ristolainen H, Gentile M, Sjöberg J, Vahteristo P & Aaltonen LA. Characterization of Uterine Leiomyomas by Whole Genome Sequencing. New England Journal of Medicine 369, 43-53, 2013. IF 158.5. Times cited 226.\\
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305. Berta DG, Kuisma H, Välimäki N, Räisänen M, Jäntti M, Pasanen A, Karhu A, Kaukomaa J, Taira A, Cajuso T, Nieminen S, Penttinen R-M, Ahonen S, Lehtonen R, Mehine M, Vahteristo P, Jalkanen J, Sahu B, Ravantti J, Mäkinen N, Rajamäki K, Palin K, Taipale J, Heikinheimo O, Bützow R, Kaasinen E & Aaltonen LA. Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma. Nature 596, 398-403, 2021. IF 64.8. Times cited 43.\\
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310. Kolterud Å, Välimäki N, Kuisma H, Patomo J, Ilves S, Mäkinen N, Kaukomaa J, Palin K, Kaasinen E, Karhu A, Pasanen A, Bützow R, Heikinheimo O, Kopp Kallner H & Aaltonen LA. Molecular Subclass of Uterine Fibroids Predicts Tumor Shrinkage in Response to Ulipristal Acetate. Human Molecular Genetics Mar 20;32(7):1063-1071, 2023. IF 3.5. Times cited 5.\\ \\[{ALLOW view All}][{ALLOW edit laaltonen}][{ALLOW upload laaltonen}][{ALLOW comment All}]