!!Mauro Perretti - Major publications \\ [List of Publications 2007-2011|Publicationsfrom2007Perretti.pdf] \\ \\ 1 __Perretti M__, Croxtall JD, Wheller SK, Goulding NJ, Hannon R. & Flower RJ: Mobilisation of lipocortin 1 in adherent human polymorphonuclear leukocytes negatively modulates their transmigration. ''NATURE MED'' 2: 1259-1262, 1996. \\ \\ 2 Lim HK, Solito E, Russo-Marie F, Flower RJ & __Perretti M__: Detachment of leukocytes adherent to murine post-capillary venules as a novel target to control inflammation: effect of lipocortin 1. ''PROC NATL ACAD SCI USA'' 95: 14535-14539, 1998. \\ \\ 3 Getting SJ, Gibbs L, Clark AJ, Flower RJ & __Perretti M__: POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. ''J IMMUNOL'' 162: 7446-7453, 1999. \\ \\ 4 Paul-Clark MJ, Mancini L, Del Soldato P, Flower RJ & __Perretti M__: Potent antiaithritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. ''PROC NATL ACAD SCI USA'' 99: 1677-1682, 2002. (__Highlighted in News & Views, Nature Review Drug Discovery__ ''No bones about it''. NRDD 2002) \\ \\ 5 __Perretti M__, Chiang N, La M, Fierro IM, Marullo S, Getting SJ, Solito E & Serhan CN. Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. ''NATURE MED'' 8: 1296-1302, 2002. \\ \\ 6 Gavins FNE, Yona S, Kamal AM, Flower RJ & __Perretti M__: Leukocyte anti-adhesive actions ofannexin 1: ALXR and FPR related anti-inflammatory mechanisms. ''BLOOD'' 101: 4140-4147, 2003. \\ \\ 7 Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D & __Perretti M__: Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions underflow: indication of distinct receptor involvement. ''BLOOD'' 107: 2123-2230, 2006. (__Highlighted by Blood with a Capsule: Serhan CN, Chiang N:__ ''Putting the brakes on neutrophils'' __Blood__ 107: 1742-1743, 2006). \\ \\ 8 D’Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley CD, Flower RJ & __Perretti M__: Annexin 1 modulates T cell activation and differentiation, ''BLOOD'' 109:1095-102, 2007. \\ \\ 9 Vong L, D’Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat V & __Perretti M__: Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. ''J BIOL CHEM ''282:29998-30004, 2007. \\ \\ 10 __Perretti M__, D’Acquisto. Annexin Al and glucocoiticoids as effectors of the resolution of inflammation. ''NAT REV IMMUNOL'' 9: 62-70, 2009.