!!Irma Paula Nathalia Thesleff 
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Selected publications 1990-2008 (out of a list of over 270)
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Vainio, S., Karavanova, I., Jowett, A., Thesleff, I. 
Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. __Cell__ 75: 45-58, 1993.
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Jowett, A.K., Vainio, S., Ferguson, M.W.J., Sharpe, P.T., Thesleff,I. Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. __Development__ 117: 461-470, 1993.
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Mitsiadis, T., Muramatsu, T., Muramatsu, H., Thesleff, I. Midkine (MK), a heparing-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. __J Cell Biol__. 129: 267-281, 1995
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Mitsiadis, T.A., Lardelli, M., Lendahl, U., Thesleff, I. Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. __J. Cell Biol__. 130: 407-418, 1995.
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Jernvall, J., Åberg, T., Kettunen, P., Keränen, S., Thesleff, I.  
The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. __Development__ 125:161-169, 1998
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Kim, H-J., Rice, D.P.C., Kettunen, P.J., Thesleff, I. 
FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development. __Development__ 125:1241-1251, 1998
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D´Souza, R.N., Åberg, T., Gaikwad, J., Cavender, A., Owen , M., Karsenty, G.,Thesleff, I. 
Cbfa 1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. __Development__ 126:2911-2920, 1999
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Mikkola, M., Pispa, J., Pekkanen, M., Paulin, L., Nieminen, P., Kere, J., Thesleff, I.
Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion. __Mech. Dev.__ 88:133-146, 1999
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Harada, H., Kettunen, P., Jung, H-S., Mustonen, T., Wang, Y.A., Thesleff, I.
Localization of putative stem cells in dental epithelium and their association Notch and FGF signaling. __J. Cell Biol__. 147:105-120, 1999
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Pispa, J., Jung, H-S., Jernvall, J., Kettunen, P., Mustonen, T., Kere, J., Thesleff, I.
Cusp patterning defect in Tabby mice teeth and its partial rescue by FGF. __Dev. Biol.__ 216:521-534, 1999
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Rice, P., Åberg. T., Chan, Y-S., Kettunen, P., Pakarinen, L., Maxson, R.E., Thesleff,I.
Integration of FGF and TWIST in calvarial bone and suture development. __Development__ 127:1845-1855, 2000
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Jernvall, J., Keränen, S.V.E., Thesleff, I. Evolutionary modification of development in mammalian teeth: Quantifying gene expression patterns and topography. __Proc. Nat. Acad. Sci. USA__ 97:14444-14448, 2000
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Jernvall, J., Thesleff, I.  Reiterative signaling and patterning in mammalian tooth morphogenesis. Mech. Dev. 92: 19-29, 2000.
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Laurikkala, J., Mikkola, M., Mustonen, T., Åberg, T., Koppinen, P., Pispa, J., Nieminen, P., Galceran, J., Grosshedl, R., Thesleff, I. TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during organogenesis. __Dev.Biol__. 229: 443-455,2001
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Laurikkala J, Pispa, J., Jung  H-S, Nieminen P, Mikkola M, Wang X, Saarialho-Kere U., Galceran, J., Grosschedl, R., Thesleff I. Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. __Development__ 129:2541-2553, 2002
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Mustonen, T., Tummers, M., Mikami, T., Itoh, N., Zhang, N., Gridley, T., Thesleff, I.   Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. __Dev. Biol__. 248:281-293, 2002
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Tummers,M. and Thesleff, I.: Root or crown: a developmental choice orchestrated by the
differential regulation of the epithelial stem cell niche in the tooth of two rodent species. 
__Development__ 130:1049-1057, 2003.
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Mustonen, T. Pummila, M., Kangas, A., Mikkola, M. Pakkasjärvi, L., Pispa, J., Jaatinen, R., Thesleff, I.:  Ectodysplasin-A1 stimulates the development of ectodermal organs.  __Dev. Biol.__ 253: 123-136, 2003
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Pispa, J., Thesleff, I.: Mechanisms of ectodermal organogenesis. __Dev. Biol__. 262: 195-205, 2003
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Laurikkala, J., Kassai, Y., Pakkasjärvi, L., Thesleff, I., Itoh, N.: Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF and SHH signals from the tooth enamel knot. __Dev. Biol__. 264: 91-105, 2003
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Lammi, L., Arte, S., Somer, M., Järvinen, H., Lahermo, P., Thesleff, I., Pirinen, S., Nieminen, P.:
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. __Am. J.
Hum. Genet.__ 74: 1043-50, 2004
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Åberg, T., Wang, X-P., Kim, J-H., Yamashiro, T., Bei, M., Rice, R., Ryoo, H-M., Thesleff, I.: Runx2 mediates FGF signalling from epithelium to mesenchyme during tooth morphogenesis. __Dev. Biol__. 270: 76-93, 2004
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Wang, X-P., Suomalainen, M., Jorgez, C.j., Matzuk, M.M., Werner, S., and Thesleff, I.: Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signalling and ameloblast differentiation. __Dev. Cell__ 7: 719-730, 2004
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Kangas, A.T., Evans, A.R., Thesleff, I., Jernvall, J.: Non-independence of mammalian dental characters. __Nature__ 432: 211-214, 2004
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Kassai, Y., Munne, P., Hotta, Y., Penttilä, E., Kavanagh, K., Ohbayashi, N., Takada, S., Thesleff, I., Jernvall, J., Itoh, N.: Regulation of mammalian cusp patterning by ectodin. __Science__ 309: 2067-2070, 2005.
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Laurikkala, J., Mikkola, M.L., James, M., Tummers, M., Mills, A., Thesleff, I.: P63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation __Development__ 133: 1553-1563, 2006.
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Järvinen, E.,  Salazaar-Ciudad, I., Birchmeier, W.,  Taketo, M.M.,  Jernvall, J., Thesleff, I. Continuous tooth generation in mouse is induced by activated epithelial Wnt/ ßcatenin signalling. __Proc. Natl. Acad. Sci USA__ 103: 18627-18632, 2006.
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Pummila, M., Fliniaux, I., Jaatinen, R., James, M., Laurikkala, J., Schneider, P., Thesleff, I.,  Mikkola, M.L. Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of BMP activity and induction of Shh expression. __Development__ 134: 117-125, 2007.
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Wang, X-P., Suomalainen, M, Felszeghy, S., Zelarayan, L.C.,  Alonso, M.T., Plikus, M.V., Maas, R., Chuong, C-M., Schimmang, T., Thesleff, I.  An integrated gene regulatory network controls epithelial stem cell proliferation in teeth. __PLoS Biology__ 5: 1324-1333, 2007
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Närhi, K., Järvinen, E, Birchmeier, W., Taketo, M., M., Mikkola, M.M., Thesleff,I. Sustained epithelial {beta}-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. __Development__ 135:1019-1028, 2008