Sir Leszek Krysztof BORYSIEWICZ#

Full CV

Present Appointments:

Vice-Chancellor Elect of the University of Cambridge (October 2010 -)
Chief Executive, Medical Research Council (October 2007 – October 2010 )
Honorary Consultant Physician (Infectious Diseases), St Mary’s NHS Trust, Praed Street, London W2 1NY (2001 - )

Awards and Honours:

• Harverian Orator (Royal College of Physicians, London) (2009)
• Sir Arthur Hall Lecturer (University of Sheffield) (2009)
• Fellow of Royal Society (2008)
• Honorary Degree of DSc – University of Southampton (2008)
• Honorary Degree of DSc – University of Hull (2008)
• Royal Society of Medicine (2007) – Jephcott Medal
• Fellow of Cardiff University (2006)
• Fellow of the City and Guilds of London Institute (2004)
• Member of the Lister Institute (2004)
• Member of Cancer Research UK, following service as a member of Council and Trustee (2004)
• Honorary Fellow of Wolfson College, Cambridge (2002)
• FRCPath (London) Honorary Fellowship (2002)
• Royal College of Physicians (London) Moxon Trust Medal (2002)
• KBE (2001)
• Founder Fellow of the Academy of Medical Sciences (1998)
• Foreign Member of the Faculty of Natural Sciences of the Polish Academy of Arts and Sciences at Krakow (1998)
• Royal College of Surgeons of England, Sir Arthur Sims Commonwealth Travelling Professorship (1997)

Education and Qualifications:

• FRCP (London) (1989)
• PhD (London) (1986)
• MRCP (UK) (1979)
• MB, B Ch with Honours (1975)
• BSc First Class Hons in Anatomy (1972)
• Welsh National School of Medicine (1969 – 1975)
• Cardiff High School for Boys (1962 – 1969) -10 GCE’O’ levels/3 GCE’A’ levels

Previous Chair/Membership of distinguished Committees:

Chairman of the HEFCE RAE 2008 Main Panel A Assessment Panel (2005 - 2009)
Member of Singapore Biomedical Sciences International Advisory Council (BMS AC) (2008 - )
Member of Medical Research Council Technology (2007 - )
Member of Health Innovation Council (2008 - )
Chairman, UK Stem Cell Funder’s Forum (2007 - )
Chairman, Heads of International (Biomedical) Research Organisations (2007 - )
Member, Global Science and Innovation Forum (GSIF) (2008 - )
Vice President, European Heads of Research Council (EUROHORCs) (2007 - )

AMRC and other organisations:

• Trustee, Nuffield Trust, London (2002 – 2007)
• Chairman Science Committee, Cancer Research UK (2002 – 2004)
• Member of Council and Trustee, Cancer Research UK (2002 – 2005)
• Member of General Purposes Committee, Cancer Research UK (2004 – 2005)
• Chairman of the British Heart Foundation Cardiovascular Research Review (2001–2002)
• Member of Council – Academy of Medical Sciences (1997-2002) [elected nationally]
• Member of the Policy Evaluation Advisory Group, The Nuffield Trust (1998 – 2005)
• Member of Wellcome Trust Monitoring Committee for clinical research facilities (1998 - 2000)
• Member of the Linbury Trust Scientific Advisory Committee (1997 - )
• Member of Lister Institute of Preventative Medicine Scientific Advisory Committee (1996 – 2002)
• Member of Medical Advisory Committee of the British Council (1995 – 2001)
• Chairman of the joint MRC/DH Research Advisory Committee on Transmissible Spongiform Encephalopathies (1996-2002)
• Member, then Chairman of the Joint Medical Advisory Committee (NHS and HEFCE) (2000-2005)
• Chairman of the Unit of Assessment Panel for Hospital Based Subjects in Research Assessment Exercise (2001) HEFCE (1998-2002) and Panel Member (1994-1998)
• Board Member of the Kidney Research Unit Fund for Wales (1995 – 2000
• Board Member of the Foundation for Nephrology (1995 – 2000)
• Member of the Lister Institute of Preventive Medicine (1994 - )
• Chairman of Linbury Trust Scientific Advisory Committee (1992-1996)
• Member Wellcome Trust Clinical Interest Group (1991 – 1994)
• Member of Council of National Kidney Research Fund (1991-1996)
• Chairman of NHS (Wales) R & D Grants Committee (1994-1998)
• Acting Director of NHS (Wales) Research & Development (1994-1996)
• Member of the Chief Executive’s Advisory Committee on Research Relevant to Health in Developing Societies (1997)
• Member Wellcome Trust Panel on Infection and Immunity (1990 – 1995)
• Advisory Panel to Linbury Trust (1990 – 1992)

Research and Grant awarding organisations:

• Member of Council; Chairman of the Molecular and Cell Board (1996 – 2000) and member of the Physiological Medicine Board (1995-6) of the Medical Research Council (1995-2000)
• Member of Council of the Medical Research Council (1995 – 2000)
• Chairman of the Molecular and Cell Medicine Board. These duties include not only chairing MCMB Meetings but being Board representative to Council, SDG, AAG etc. I have chaired ~16 Unit Scientific Reviews and Site Visits, ~10 Appointment Committees, 5 reviews linked to establishing new Units and participated in ~15 sub-committees dealing with specific MCMB related matters (1996 – 2000)
• Member of MRC Cardiovascular Advisory Group (2001-2002)
• Chairman MRC Vaccine Development Group (1991 – 2002)
  

University:

• Trustee of St Mark’s Hospital Foundation (2003 -2004)
• Observer of West London Development Workforce Confederation HEI Group (2002 – 2004)
• Chairman of the Joint Medical Advisory Committee (NHS and HEFCE) (2002 – 2004)
• Member of Schistosomiasis Control Initiative (SCI) Board of Directors (2002 – 2007)
• Member of the HEFCE RAE Review Steering Group (Chaired by Gareth Roberts) (2001 – 2002)
• Principal, Faculty of Medicine and Imperial College School of Medicine. The appointment as Principal requires me to Chair all Faculty Advisory Committees and to: represent the Faculty at most College Commitees, Senate, Court and Council, including the Executive Committee. (2001 – 2004)
• Observer of Hammersmith Hospitals NHS Trust Board (2001– 2004)
• Member of North West London Acute Chief Executive Forum (2001 – 2005)
• Member of West London Pathology Consortium (2001–2004)
• Chairman of the Unit of Assessment Panel for Hospital Based Subjects in Research Assessment Exercise (2001) HEFC(E) (1998 -2002)
• HEFC(E) member of the Research Assessment Excercise Panel – Hospital based Subjects (1995 – 1996)
• Member of Board of Advisors - Standing Panel of Experts in Medicine, University of London (1993 – 2001)

Clinical and other advisory organisations:

• Member, Expert Scientific Group – Clinical Trial TGN 1412, Medicines and Healthcare products Regulatory Agency (2005 - 2007)
• Chairman UKCRC Integrated Academic Training (2005 – 2007)
• Member of Royal College of Physicians’ Advisory Committee on Higher Awards (2000)
• Member of the Specialist Advisory Committee in Genitourinary Medicine, Royal College of Physicians (1991 – 2001)
• Member of the Royal Colleges Joint Committee on Infection (1998 – 2000)
• Member of panel advising Ministry of Defence on health consequences of service during Gulf War (1996)
• Member of the Joint Working Party (College of Psychiatrists and Physicians) on Chronic Fatigue Syndrome (1995 – 1996)
• Member of Research Committee of the Royal College of Physicians (1995 – 1997)
• Chairman Specialist Advisory Committee on Infection and Tropical Medicine (1994 –2001)
• Member Royal College of Physicians' Joint Committee on Higher Medical Training (1994 – 2001)
• Member of Department of Health Expert Advisory Group on AIDS (1993 -1997)
• Member of Department of Health Expert Group for Hammersmith & Queen Charlotte's SHA (1993)
• Welsh representative on Joint Medical Advisory Committee (JMAC) of Higher Education Funding Councils (2000 – 2001)
• Member of the NHS R & D Consortium Committee of the Vale and UHW Trust (1998 - 2001)

Europe and International:

• Chairman of Scientific Council of International Agency for Research on Cancer (WHO) (2002 – 2004)
• Vice Chairman of Scientific Council of International Agency for Research on Cancer (WHO) (2001 – 2002)
• Member of Scientific Council of International Agency for Research on Cancer, WHO (2000- 2004)
• EU Advisory group on Transmissible Spongiform Encephalopathies (1996)
• Member of SmithKline Beecham Biologicals/Regional Government - Walloon Region, Belgium, Scientific Advisory Committee for Centre for Inter-University Vaccine Research (CRIV) (1995 – 2004)

Industrial:

• Member of Oxxon Pharmaccines Limited Scientific Advisory Board (2002 – 2004)
• Member of Scientific Advisory Board for Cancer Research Ventures Limited (2000-2002)
• Consultant to Cantab Pharmaceuticals PLC (1991-2000)
• Consultant to Smith Kline Beecham RIT (Belgium) in cell mediated anti-viral immune responses and vaccine development (1998)

Editorial:

• Member of the Editorial Board of Viral Immunology (2000)
• Member of the Editorial Board – Microbes and Infection, Pasteur Institute, Paris (1998)
• Specialist Advisor to the Journal of Infection (1997)
• Series Editor, British Medical Board (1997 – 2001)
• Member of Editorial Board of British Medical Bulletin (now Series Editor) (1995 – 2007)
• Member Editorial Board Infectious Diseases, Baillière Tindall (1994-2000)
• Member Editorial Board, Quarterly Journal of Medicine (1992 – 1997)
• Member of International Scientific Council of Immunologia Polska Journal (now the Central European Journal of Immunology) (1991 - )
• Member of Editorial Board-Journal of Immunological Methods (1981 – 2001)
• Member of the Editorial Board – Autoimmunity: Harwood Academic Publishers-London, Paris, New York (1987 -2000)

Previous Appointments/Professional Experience:

• 2004 – October 2007 Deputy Rector, Imperial College London, Imperial College Road, London SW7 2AZ
• 2006 - 2007 Governor, Wellcome Trust
• 2005 - 2007 Chairman Joint MRC/UK Stem Cell Foundation Scientific Advisory Board
• 2005 - 2007 Chairman UKCRC Integrated Academic Training Awards Panel
• 2002 - 2007 Trustee, Nuffield Trust, London
• 2001- Oct 2004 Principal, Faculty of Medicine and Imperial College School of Medicine, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, Imperial College Road, London SW7 2AZ
• 2003- 2004 Non Executive Director, North Thames Regional Health Authority, Victory House, 170 Tottenham Court Road, London
• 2001 - 2003 Non Executive Director, Chelsea and Westminster Healthcare NHS Trust, 369 Fulham Road, London SW10 9NH
• 1999- 2001 Professor of Medicine, University of Wales College of Medicine, Cardiff. Honorary Consultant Physician (Infectious Diseases), University Hospital of Wales, Cardiff
• 1995- 2001 Honorary Consultant Physician, Cardiff Community Healthcare NHS Trust
• Honorary Consultant Physician, Llandough Hospital Trust
• Honorary Consultant Physician, Velindre Hospital Trust
• 1989-1990 Honorary Consultant Physician to Papworth Hospital, Huntingdon
• 1988-1990 University Lecturer in Department of Medicine and Honorary Consultant Physician (Infectious Diseases) University of Cambridge, Addenbrooke's Hospital, Cambridge
• 1988-1988 Wellcome Trust Senior Lecturer in Infectious Diseases and Honorary Consultant Physician, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge
• 1987-1987 Lister Research Fellow and Honorary Consultant Physician, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge
• 1987-1987 Lister Research Fellow/Honorary Senior Lecturer and Consultant Physician (Infectious Diseases), Department of Medicine, Royal Postgraduate Medical School and Hammersmith Hospital, London W12
• 1986-1987 Senior Registrar to the Renal and Infectious Diseases Unit (Professor DK Peters, Dr J Cohen et al) Hammersmith Hospital and Royal Postgraduate Medical School, London W12
• 1986 Consultant Physician at The Royal Victoria Hospital, Banjul, The Gambia
• 1982-1986 Lister Research Fellow, Honorary Senior Registrar and Lecturer in Medicine, Royal Postgraduate Medical School and Hammersmith Hospital
• 1980-1982 MRC Training Fellowship Award (until October 1983) Research Fellow and Honorary Registrar to Department of Medicine (Renal) Professor DK Peters and Dr JGP Sissons, Royal Postgraduate Medical School and Hammersmith Hospital
• 1979-1980 Registrar in Renal Medicine and Immunology to Professor DK Peters, Dr AJ Rees and Dr C Spry, Hammersmith Hospital and Royal Postgraduate Medical School
• 1978-1979 Registrar in General Medicine, Cardiology and Gastroenterology to Dr D Krikler and Dr H McMichael, The Ealing Hospital
• 1978-1978 Senior House Officer in Neurology to Dr CJ Earl, Sir R Bannister and Dr R Kocen at National Hospital for Nervous Diseases, Queen's Square
• 1977-1978 Senior House Officer in Medicine (Renal and Immunology) to Professor DK Peters and Dr C Spry at Hammersmith Hospital and Royal Postgraduate Medical School
• 1977-1977 Senior House Officer to Profesor AW Asscher in General and Renal Medicine, Cardiff Royal Infirmary, Cardiff
• 1976-1977 Senior House Officer to Department of Neurology Dr CE Wells and Dr J Graham at University Hospital of Wales, Cardiff
• 1976-1976 House Surgeon to the Surgical Unit Mr M Baum, University Hospital of Wales and Cardiff Royal Infirmary, Cardiff
• 1975-1976 House Officer to the Medical Unit Dr T Hayes & Dr J Picton Thomas at University Hospital of Wales, Cardiff

Distinguished Lectures

2008

• Cardiff Medical Society - “The Global Health Agenda”
• Neath Port Talbot Local Health Board, Protected Time for Learning – “Cancer Vaccines from Bench to Policy”
• EMRC White Paper Briefing Conference - Present Status & Future Strategy for Medical Research in Europe - 'National Institutes of Health and Medical Research Councils
• Inaugural meeting of newly established MRC Neuromuscular Translational Research Centre at UCL/Institute of Neurology/Institute of Child Health and Newcastle University – “Translational Reseach in UK”
• Cardiff for Africa – ‘Global Health Initiatives – are the Research Priorities Changing?’
• Association of Physicians of Great Britain and Ireland, Annual Meeting – ‘MRC-NIHR academic initiative’
• International meeting for Autism Research - 'The Role of the Medical Research Council in Supporting Autism Research in the UK'
• Cancer Research UK Senior Leadership Conference 'Together' – ‘MRC and Cancer Research UK Working Together’
• Clinical Trials Conference - 'Accelerating Bench-to-Bedside' - William Harvey Research Institute, Barts and the London NHS Trust
• Peninsula College of Medicine and Dentistry – ‘The MRC and Biomedical Science – where next?’ 2007
• The Lord Phillips Memorial Lecture, Cardiff University and Cardiff Scientific Society Lecture: “AIDS as the Modern Plague”
• TU Delft 165th ‘Dies Natalis’: “Universities and the Global Health Agenda”
• Centenary Lecture, Kampala, Uganda: “Imperial College Centenary: Past, Present and Future”
• Conference of Medical Academic Representatives 2007, BMA: “Integrated Academic Training Pathway”
• Jephcott Symposium, The Royal Society of Medicine: “Cancer prevention: vaccine-based approaches
• Annual ABPI lecture - "Universities, the Pharmaceutical Industry and the Global Health Agenda"
• Ministerial Launch of the DIUS Science Budget Allocations to 2010/2011 –“Ageing: Lifelong health and well-being; Stem cells & regenerative medicine”
• West Kent Medico-Chirurgical Society – “Improving Health in the Developing World”

2006

• Commercialisation of Stem Cells: “From Bench to Bedside - How to make the Translational Leap”
• Science & Technology Seminar, Centre for China in the World Economy, School of Economics and Management, Tsinghua University: “The Academic Mission”
• University of Manchester: “HPV and Cervical Cancer in the Developing World”
• Centre for Integration of Medicine and Innovation Technology (CIMIT):
• St John’s Hospital Dermatological Society:
• Athenaeum: “Whither Medical Education?”
• CORE: “Developing Academic Medical Careers”

2005

• The Opening ceremony of Leeds Institute of Genetics, Health and Theraputics Lab: “The Challenges and Opportunities for Academic Medicine”
• Royal College of Physicians Regional Update in South Wales: Bradshaw lecture “The Global Public Health Challenge”
• Royal Society Equality Challenge Athena Conference: “Maximising UK Assets”

2004

• The Genomics and Proteomics Revolution: Vaccine Development, Drug Design, and Delivery: “Anti-cancer vaccines – implications for developing countries”
• Annual General Meeting of the German Society of Internal Medicine: “The Situation of Clinical Research in the United Kingdom”
• BHF Cardiovascular Forum: “The British Medical School – Where Next?”
• Meeting for Clincial Scientists in Training: “The International Opportunity and Agenda – a Role for Academic Medicine”
• University of Warwick, Turberg lecture: “'How can we engage with Global Public Health issues?”
• Atlantic College: “Causes and Consequences of HIV and AIDS”

2003

• Association of Clinical Professors. ‘The Future of the RAE - Lessons from 2001'
• Association of Professors of Obsetrics & Gynaecology.
• University of Leeds. “Career Development Workshop: ‘Academic Career Development in the 21st Century – What is an Academic?’”
• MRC Strategy Development Group Meeting: “Infection: A Model for Change”
• Fouth Advanced Course of Vaccinology – 2003 (Annecy): “Prospects for HPV vaccines and prevention of cervical cancer”
• Association of Clincial Pathologists: “Vaccination against Cancer”
• University of Bologna: “Vaccines for the Prevention of Cancer”
• HPV Vaccines & Immunotherapies Symposium: “Vaccine development from bench to field. Can cervical cancer be prevented?”
• Health Services Journal ‘Joining up Health Symposium’: Medical Advances
• University of Wales College of Medicine public lecture: “AIDS: The Modern Plague”
• Trinity College, Oxford ‘From the Laboratory to the Clinic’: HPV Vaccine Studies”

2002

• The Royal College of Pathologists. “Protecting the public from Infections, Chemicals and Radiological Hazards”
• Bolton and District Medical Society. “Cervical Cancer”
• Abingworth Management Scientific Advisory Group, London. “Infectious Diseases: A Clinical Viewpoint”
• IC and Universities UK, London. “Future Directions in Health Education”
• South Western Laryngological Association 2002 William Memorial Lecture, Wales. “Infectious Disease and the Surgeon”
• Society for General Microbiology – Workshop on Papillomaviruses, Warwick. Virus Infection in Immunocompromised and Transplant Patients’
• SmithKlineBeecham Symposium, Belgium.
• National Cancer Institute, HPV Immunology Workshop, Rockville, Maryland USA. “The role of Human CD8 Cytotoxic T Cells in Control of HPV Associated Malignancy”
• Institute of Welsh Affairs, Swansea. “The Research Focus”

2001

• British Geriatrics Society, Cardiff. “HIV in the Elderly”
• RAND Corporation/Nuffield Trust, Santa Monica, California. “Future development of Biomedical Research and Education”
• Royal College of Physicians, London. “Clinical Research in Action”
• British Association of Dermatologists, Cardiff. Human Pappilomarvirus Infection
• International Congress of Immunology, Stockholm. “Viral Infections and Viral Immunity”
• Edinburgh Virology Symposium, Edinburgh. “Development of Antiviral Cancer Vaccine to HPV”

2000

• Glaxo Wellcome Seminar: “Immune responses to human papillomaviruses – implications for vaccines”
• Royal College of Physicians, London, Advanced Medicine Conference: “Vaccine strategies for cancer”
• Association of Clinical Professors Meeting (Royal College of Physicians, London): “RAE update”
• British Transplant Society, Cardiff – Opening Plenary Presentation: “Viral infection post transplantation with CMV/EBV”
• Vth EUROGIN meeting, Paris: “Use of vaccines recombinants to express HPV 16 proteins: results of phase I/II clinical trials”
• EFIS 2000, Poland; Satellite symposium on “Infectious Immunity and Vaccines”: Title of talk: “Viral evasion of innate immunity”
• ICCAC Meeting, Toronto, Canda; invited speaker: “Measurement of specific T cell immunity”
• Festival of Medicine Keynote Conference; invited speaker: “Development of anti-cancer vaccines”

1999

• WHO Geneva; Global programme for vaccines and immunisation: Title of lecture given “Regulatory and ethical issues related to HPV vaccination”
• British Society for Investigative Dermatology Annual meeting: “Human papillomavirus infection and cancer; prospects for prevention”
• European Renal Association in Madrid: “Vaccines against human papillomavirus”
• From the Laboratory to the Clinic, Trinity College, Oxford: “Immunotherapy of human virus associated cancers”
• William Harvey Lecture, St Bartholomew’s: “Vaccines for cancer: myth or reality?”

1998

• University of Leicester, Department of Immunology Seminar: “Towards the development of human anti-cancer therapeutic vaccines”
• Department of Immunology, King’s College Medical School: “Virus specific cytotoxic T cells”
• Ziekenhuis Academisch, Free University of Amsterdam: “HPV specific CTL Immunity”
• Glaxo Wellcome Seminar: “CMV and the host: evasion and immunopathology”
• St George’s Hospital, London Guest lecture: “Vaccines and cancer”
• Imperial College, St Mary’s Seminar: “HPV specific CTL”
• BMA Conference, Cardiff – Science and Medicine: “Anti-cancer vaccines”
• EACR meeting, Stockholm: “HPV specific immunity and development of cervical cancer vaccines”
• Cervical Cancer Vaccine Meeting National Institute of Health, Bethesda, USA: “HPV specific CTL immunity”
• SKB Symposium, Belgium: “Herpes Viruses”
• University Hospital Birmingham, Respiratory Seminar programme: “Virology and the lung”
• Royal College of Physicians, Science & Medicine Conference Talk: “CMV”

Membership of Societies

• Association of Clinical Professors of Medicine
• Bologna Medical and Surgical Society
• British Society for Immunology
• Society for General Microbiology
• Infectious Disease Society (now merged with British Society for Infection – Treasurer 1992-4)
• Medical Research Club
• Association of Physicians (UK) – Executive Committee Member(1995-98)
• American Society of Immunology
• Society of Physicians in Wales
• 1942 Club

Interests
Rugby football, cricket, oil painting
Married to Dr Gwenllian S Jones, with two daughters Catherine (b1979) and Rachel (b1982)
Date of Birth: 13 April 1951, Cardiff