Emmanuelle Charpentier - Selected Publications#

A versatile regulatory toolkit of arabinose-inducible artificial transcription factors for Enterobacteriaceae.
Naseri G, Raasch H, Charpentier E, Erhardt M.
Commun Biol. 2023 Oct 3;6(1):1005.
doi: 10.1038/s42003-023-05363-3.

Methodologies for bacterial ribonuclease characterization using RNA-seq.
Broglia L, Le Rhun A, Charpentier E.
FEMS Microbiol Rev. 2023 Sep 5;47(5):fuad049.
doi: 10.1093/femsre/fuad049.

Time-Resolved Proteome Analysis of Listeria monocytogenes during Infection Reveals the Role of the AAA+ Chaperone ClpC for Host Cell Adaptation.
Birk MS, Ahmed-Begrich R, Tran S, Elsholz AKW, Frese CK, Charpentier E.
mSystems. 2021 Aug 31;6(4):e0021521.
doi: 10.1128/mSystems.

An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3'-to-5' exoRNases and RNase Y.
Broglia L, Lécrivain AL, Renault TT, Hahnke K, Ahmed-Begrich R, Le Rhun A, Charpentier E.
Nat Commun. 2020 Mar 27;11(1):1587.
doi: 10.1038/s41467-020-15387-6.

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches.
Bratovič M, Fonfara I, Chylinski K, Gálvez EJC, Sullivan TJ, Boerno S, Timmermann B, Boettcher M, Charpentier E.Nat Chem Biol. 2020 May;16(5):587-595.
doi: 10.1038/s41589-020-0490-4.

Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence.
Ratner HK, Escalera-Maurer A, Le Rhun A, Jaggavarapu S, Wozniak JE, Crispell EK, Charpentier E, Weiss DS.
Mol Cell. 2019 Aug 8;75(3):498-510.e5.
doi: 10.1016/j.molcel.2019.05.029.

In vivo 3'-to-5' exoribonuclease targetomes of Streptococcus pyogenes.
Lécrivain AL, Le Rhun A, Renault TT, Ahmed-Begrich R, Hahnke K, Charpentier E.
Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11814-11819.
doi: 10.1073/pnas.1809663115.

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.
Fonfara I, Richter H, Bratovič M, Le Rhun A, Charpentier E.
Nature. 2016 Apr 28;532(7600):517-21.
doi: 10.1038/nature17945.

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E.
Science. 2012 Aug 17;337(6096):816-21.
doi: 10.1126/science.1225829.

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.
Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E.
Nature 2011 Mar 31;471(7340):602-7.
doi: 10.1038/nature09886.