Guillaume Duménil - Selected Publications#

Aubey F, Corre JP, Kong Y, Xu X, Obino D, Goussard S, Lapeyrere C, Souphron J, Couturier C, Renard S, Dumenil G (2019) Inhibitors of the Neisseria meningitidis PilF ATPase provoke type IV pilus disassembly. Proc Natl Acad Sci U S A 116: 8481-8486.

Dumenil G (2019) Type IV Pili as a Therapeutic Target. Trends Microbiol.

Kennouche P, Charles-Orszag A, Nishiguchi D, Goussard S, Imhaus AF, Dupré M, Chamot-Rooke J, Duménil G (2019) Deep mutational scanning of the Neisseria meningitis major pilin reveals the importance of pilus tip-mediated adhesion. EMBO J In press.

Obino D, Dumenil G (2019) The Many Faces of Bacterium-Endothelium Interactions during Systemic Infections. Microbiol Spectr 7.

Bonazzi D, Lo Schiavo V, Machata S, Djafer-Cherif I, Nivoit P, Manriquez V, Tanimoto H, Husson J, Henry N, Chate H, Voituriez R, Dumenil G (2018) Intermittent Pili-Mediated Forces Fluidize Neisseria meningitidis Aggregates Promoting Vascular Colonization. Cell 174: 143-155 e116.

Charles-Orszag A, Tsai FC, Bonazzi D, Manriquez V, Sachse M, Mallet A, Salles A, Melican K, Staneva R, Bertin A, Millien C, Goussard S, Lafaye P, Shorte S, Piel M, Krijnse-Locker J, Brochard-Wyart F, Bassereau P, Dumenil G (2018) Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting. Nat Commun 9: 4450.

Charles-Orszag A, Lemichez E, Tran Van Nhieu G, Dumenil G (2016) Microbial pathogenesis meets biomechanics. Curr Opin Cell Biol 38: 31-37.

Gault J, Ferber M, Machata S, Imhaus AF, Malosse C, Charles-Orszag A, Millien C, Bouvier G, Bardiaux B, Pehau-Arnaudet G, Klinge K, Podglajen I, Ploy MC, Seifert HS, Nilges M, Chamot-Rooke J, Dumenil G (2015) Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation. PLoS Pathog 11: e1005162.

Imhaus AF, Dumenil G (2014) The number of Neisseria meningitidis type IV pili determines host cell interaction. EMBO J 33: 1767-1783.

Chamot-Rooke J, Mikaty G, Malosse C, Soyer M, Dumont A, Gault J, Imhaus AF, Martin P, Trellet M, Clary G, Chafey P, Camoin L, Nilges M, Nassif X, Dumenil G (2011) Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination. Science 331: 778-782.