George Klein - List of publications#

• Georg Klein Publications 1951-1980
• Georg Klein Publications 1980-1995
• Georg Klein Publications 1996-2006
• Georg Klein Publications 1995-2008

• Rasul AE, Nagy N, Sohlberg E, Adori M, Claesson HE, Klein G, Klein E - Simultaneous detection of the two main proliferation driving EBV encoded proteins, EBNA-2 and LMP-1 in single B cells, J Immunol Methods. 2012 Aug 18
• Cheng HH, Kuo CC, Yan JL, Chen HL, Lin WC, Wang KH, Tsai KK, Guvén H, Flaberg E, Szekely L, Klein G, Wu KK - Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan. Proc Natl Acad Sci U S A. 2012 Jul 31
• Darekar S, Georgiou K, Yurchenko M, Yenamandra SP, Chachami G, Simos G, Klein G, Kashuba E. - Epstein-barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the warburg effect, PLoS One. 2012;7(7):e42072
• Genetic and epigenetic analysis of non-small cell lung cancer with NotI-microarrays Dmitriev AA, Kashuba VI, Haraldson K, Senchenko VN, Pavlova TV, Kudryavtseva AV, Anedchenko EA, Krasnov GS, Pronina IV, Loginov VI, Kondratieva TT, Kazubskaya TP, Braga EA, Yenamandra SP, Ignatjev I, Ernberg I, Klein G, Lerman MI, Zabarovsky ER - Epigenetics. 2012 May 1;7(5)
• Flaberg E, Guven H, Savchenko A, Pavlova T, Kashuba V, Szekely L, Klein G - The architecture of fibroblast monolayers of different origin differentially influences tumor cell growth Int J Cancer. 2012 Mar 7. doi: 10.1002/ijc.27521
• Salamon D, Adori M, Ujvari D, Wu L, Kis LL, Madapura HS, Nagy N, Klein G, Klein E. - Latency-type dependent modulation of Epstein-Barr virus encoded latent membrane protein 1 expression by type I interferons in B cells. J Virol. 2012 Feb 15
• Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvári D, Madapura HS, Leveau B, Klein G, Klein E. - Soluble factors produced by activated CD4+ T cells modulate EBV latency Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1512-7
• Yenamandra SP, Darekar SD, Kashuba V, Matskova L, Klein G, Kashuba E. - Stem cell gene expression in MRPS18-2-immortalized rat embryonic fibroblasts. Cell Death Dis. 2012 Jan 19;3:e357. doi: 10.1038/cddis.2011.138.
• Salamon D, Adori M, He M, Bönelt P, Severinson E, Kis LL, Wu L, Ujvari D, Leveau B, Nagy N, Klein G, Klein E. - Type I interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: Differential regulation in B cell lines derived from endemic or sporadic Burkitt's lymphoma. Cytokine. 2011 Dec 26.
• Kashuba E, Yurchenko M, Yenamandra SP, Snopok B, Szekely L, Bercovich B, Ciechanover A, Klein G. Epstein-Barr virus-encoded EBNA-5 forms trimolecular protein complexes with MDM2 and p53 and inhibits the transactivating function of p53. Int J Cancer. 2011 Feb 15;128(4):817-25. doi: 10.1002/ijc.25414.
• Yenamandra SP, Hellman U, Kempkes B, Darekar SD, Petermann S, Sculley T, Klein G, Kashuba E. Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes Cell Mol Life Sci. 2010 Dec;67(24):4249-56.
• Kis LL, Gerasimcik N, Salamon D, Persson EK, Nagy N, Klein G, Severinson E, Klein E. The STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma Blood. 2011 Jan 6;117(1):165-74. Epub 2010 Sep 27
• Flaberg E, Markasz L, Petranyi G, Stuber G, DicsQ F, Alchihabi N, Oláh E, Csízy I, Józsa T, Andrén O, Johansson JE, Andersson SO, Klein G, Szekely L. High throughput live cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts Int J Cancer. 2010 Aug 16
• Yenamandra SP, Hellman U, Kempkes B, Darekar SD, Petermann S, Sculley T, Klein G, Kashuba E. Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes Cell Mol Life Sci. 2010 Jul 1
• Klein G, Klein E, Kashuba E. Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes Biochem Biophys Res Commun. 2010 May 21;396(1):67-73
• Lacoste S, Wiechec E, Dos Santos Silva AG, Guffei A, Williams G, Lowbeer M, Benedek K, Henriksson M, Klein G, Mai S Chromosomal rearrangements after ex vivo Epstein-Barr virus (EBV) infection of human B cells. Oncogene. 2010 Jan 28;29(4):503-15.
• Kis LL, Salamon D, Persson EK, Nagy N, Scheeren FA, Spits H, Klein G, Klein E. IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):872-7.
• Klein E, Klein G Burkitt lymphoma. Semin Cancer Biol. 2009 Dec;19(6):345-6.
• Nagy N, Klein G, Klein E. To the genesis of Burkitt lymphoma: Regulation of apoptosis by EBNA-1 and SAP may determine the fate of Ig-myc translocation carrying B lymphocytes Semin Cancer Biol. 2009 Oct 27.
• Yenamandra SP, Sompallae R, Klein G, Kashuba E. Comparative analysis of the Epstein-Barr virus encoded nuclear proteins of EBNA-3 family. Comput Biol Med. 2009 Nov;39(11):1036-42.
• Nagy N, Matskova L, Kis LL, Hellman U, Klein G, Klein E. The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11966-71.
• Klein G. Burkitt lymphoma-A stalking horse for cancer research? Semin Cancer Biol. 2009 Jul 14
• Ehlin-Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A. Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection. Immunology. 2009 Aug;127(4):549-57
• Kashuba VI, Pavlova TV, Grigorieva EV, Kutsenko A, Yenamandra SP, Li J, Wang F, Protopopov AI, Zabarovska VI, Senchenko V, Haraldson K, Eshchenko T, Kobliakova J, Vorontsova O, Kuzmin I, Braga E, Blinov VM, Kisselev LL, Zeng YX, Ernberg I, Lerman MI, Klein G, Zabarovsky ER. High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer. PLoS ONE. 2009 May 29;4(5):e5231
• Stuber G, Flaberg E, Pertanyi G, Otvos R, Rokaeus N, Kashuba E, Wiman KG, Klein G, Szekely L. PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein Mol Cancer. 2009 Mar 26;8(1):23
• Klein G. Toward a genetics of cancer resistance. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):859-63.
• Liu, A., Claesson, H-E., Mahshid, Y., Klein, G., Klein, E. Leukotriene Leukotriene B4 activates T cells which inhibit B cell proliferation in EBV infected cord blood derived mononuclear cell cultures Blood 111:2693-703, 2008.
• Kashuba E, Yurchenko M, Yenamandra SP, Snopok B, Isaguliants M, Szekely L, Klein G. EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5489-94
• Darai-Ramqvist E., Sandlund A., Müller S., Klein G., Imreh S., Kost-Alimova M Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions PNAS, 18:370-379, 2008.
• Wang F. et al HYAL1 and HYAL2 inhibit tumour growth In Vivo but not In Vitro PLoSONE 22:3 2008