Bart Jan Kullberg - Selected Publications#

Peer reviewed publications 386; citations 24130; h-index 77

Innate Immunity and Host defense to Infection:

Human dectin-1 deficiency and mucocutaneous fungal infections.
Ferwerda B, Ferwerda G, Plantinga TS, Willment JA, van Spriel AB, Venselaar H, Elbers CC, Johnson MD, Cambi A, Huysamen C, Jacobs L, Jansen T, Verheijen K, Masthoff L, Morré SA, Vriend G, Williams DL, Perfect JR, Joosten LA, Wijmenga C, van der Meer JW, Adema GJ, Kullberg BJ, Brown GD, Netea MG.
N Engl J Med 2009; 361: 1760-1767

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis.
Van de Veerdonk FL, Plantinga TS, Hoischen A, Smeekens SP, Joosten LA, Gilissen C, Arts P, Rosentul DC, Carmichael AJ, Smits-van der Graaf CA, Kullberg BJ, van der Meer JW, Lilic D, Veltman JA, Netea MG.
N Engl J Med 2011; 365: 54-61.

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.
Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JW, Joosten LA, Sokol H, Bauer H, Herrmann BG, Bochud PY, Marchetti O, Perfect JR, Xavier RJ, Kullberg BJ, Wijmenga C, Netea MG.
Nat Commun 2014; 5: 4675

Immune defence against Candida fungal infections.
Netea MG, Joosten LAB, van der Meer JWM, Kullberg BJ, Van de Veerdonk FL.
Nat Rev Immunol 2015;15(10):630–42.

Treatment of Invasive Fungal Infections:

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.
Pappas PG, Kauffman CA, Andes D, Benjamin DK, Jr., Calandra TF, Edwards JE, Jr., Filler SG, Fisher JF, Kullberg BJ, Ostrosky-Zeichner L, Reboli AC, Rex JH, Walsh TJ, Sobel JD.
Clin Infect Dis 2009; 48: 503-35.

Invasive Candidiasis.
Kullberg BJ, Arendrup MC.
N Engl J Med 2015;373(15):1445–56 (invited review).

A randomized, prospective, multicenter study of voriconazole versus a regimen of amphotericin B followed by fluconazole in the treatment of candidemia in nonneutropenic patients.
Kullberg BJ, Pappas PG, Ruhnke M, Viscoli V, Sobel JD, Rex JH, Cleary JD, Rubinstein E, Church LWP, Brown JM, Schlamm HT, Oborska IT, Hilton F, Hodges MR.
Lancet 2005; 366: 1435-42.

Invasive Candidiasis.
Pappas PG, Lionakis M, Arendrup MC, Ostrosky-Zeichner L, Kullberg BJ.
Nature Reviews Disease Primers, 2018; 4: 18026 (invited review)

Lyme disease:

Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease.
Berende A, Ter Hofstede HJM, Vos FJ, van Middendorp H, Vogelaar ML, Tromp M, van den Hoogen FH, Donders ART, Evers AWM, Kullberg BJ.
N Engl J Med 2016; 374: 1209–20.

Antimicrobial Stewardship:

Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis.
Schuts EC, Hulscher MEJL, Mouton JW, Verduin CM, Stuart JWTC, Overdiek HWPM, van der Linden PD, Natsch S, Hertogh CMPM, Wolfs TFW, Schouten JA, Kullberg BJ, Prins JM.
Lancet Infect Dis 2016;16(7):847–56.