Rohini Kuner - Selected publications#

Top papers and reviews since 2006:

1. Tappe A. und Kuner R. Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family, Proc. Natl. Acad. Sci. USA. 103(3):774-9, 2006

2. Tappe A, Klugmann M, Luo C, Hirlinger D, Agarwal N, Benrath J, Ehrengruber MU, During MJ, Kuner R. Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain. Nature Medicine 12(6):677-81, 2006

3. N. Agarwal, P. Pacher, I. Tegeder, F. Amaya, C. Constantin, G. J. Brenner, T. Rubino, C.W. Michalski, G. Marsicano, K. Monory, K. Mackie, C. Marian, S. Batkai, D. Parolaro, M. J. Fischer, P. Reeh, G. Kunos, M. Kress, B. Lutz, C. J. Woolf, R. Kuner. Nociceptor-specific conditional gene deletion reveals that cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors, Nature Neuroscience, 10(7):870-9, 2007.

4. Michalski CW, Laukert T, Sauliunaite D, Pacher P, Bergmann F, Agarwal N, Su Y, Giese T, Giese NA, Bátkai S, Friess H, Kuner R. Cannabinoids ameliorate pain and reduce disease pathology in caerulein-induced acute pancreatitis. Gastroenterology 132, 1968-1978, 2007

5. Schweizerhof M., Stösser S., Kurejova M., Njoo C., Gangadharan V., Agarwal N., Schmelz, M., Bali K.K., Christoph M., Brugger S., , Dickenson A., Simone D., Kuner R. Hematopoietic colony stimulating factors mediate tumor-nerve interactions and bone cancer pain, Nature Medicine, 15(7):802-7, 2009

6. Kuner R. Central mechanisms of pathological pain. Nature Medicine 16, 1258-1266, 2010 (review)

7. Gangadharan V, Wang R, Ulzhöfer B, Luo C, Bardoni R, Bali KK, Agarwal N, Tegeder I, Hildebrandt U, Nagy GG, Todd AJ, Ghirri A, Hussler A, Sprengel R, Seeburg PH, Macdermott AB, Lewin GR, Kuner R. Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice. J Clinical Investigation, 121(4):1608-23, 2011

8. Luo C, Gangadharan V, Bali KK, Xie RG, Agarwal N, Kurejova M, Tappe-Theodor A, Tegeder I, Feil S, Lewin G, Polgar E, Todd AM, Schlossmann J, Hofmann F, Liu DL, Hu SJ, Feil R, Kuner T, Kuner R. Presynaptically localized cyclic GMP-dependent Protein Kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity. PLoS Biology, 10(3):e1001283, 2012

9. Simonetti M, Hagenston AM, Vardeh D, Freitag HE, Mauceri D, Lu J, Satagopam VP, Schneider R, Costigan M, Bading H, Kuner R. Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain. Neuron 77:43-45, 2013

10. Simonetti M., Agarwal N., Stösser S., Bali K.K. , Karaulanov E. , Kamble R. , Pospisilova B. , Kurejova M. , Birchmeier W. , Niehrs C. , Heppenstall P. , Kuner R. Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct non-canonical pathways, Neuron, in press