Yi Lyu - Curriculum Vitae#

Education

• 1979 - 1984 Xi’an Medical College Bachelor's Degree in Clinical Medicine
  
• 1987 - 1990 Xi’an Medical College Master’s Degree in General Surgery
  
• 1992 - 1995 Xi’an Medical College Doctor’s Degree in General Surgery
  
• 1998 - 2000 Nippon Medical School Hospital, Tokyo, Japan Postdoctoral Research Fellow at the Department of Surgery

Professional Experience

• 2022 - present Dean of Xi’an Jiaotong University Health Science Center
  
• 2021 - present Vice President of Xi’an Jiaotong University, Director of The First Affiliated Hospital, Xi’an Jiaotong University
  
• 2018 - present Director of National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine
  
• 2013 - 2021 Assistant President of Xi’an Jiaotong University, Associate Dean of Xi’an Jiaotong University Health Science Center
  
• 2012 - present Director of Shaanxi Center for Regenerative Medicine and Surgical Engineering
  
• 2011 - present Director of Institute of Advanced Surgical Technology and Engineering, Xi’an Jiaotong University
  
• 2011 - present Vice President of Hepatobiliary Disease Hospital
  
• 2005 - 2008 Vice President of The First Affiliated Hospital, College of Medicine, Xi’an Jiaotong University
  
• 2002 - present Professor of the Department of Hepatobiliary Surgery
  
• 2000 - present Associate Director of Institute of Organ Transplantation, Xi’an Jiaotong University

Academic Tenure and Editorship

• Fellow, American College of Surgeons
  
• Vice chairman of the Surgery Group of the Chinese Society of Surgery
  
• Executive member of the Chinese College of Surgeons
  
• President of Organ Transplantation Association of Chinese Medical Association Shaanxi Branch
  
• Chief Editor of Magnetic Surgery
  
• Chief Editor of Clinical Research and Practice (ISSN: 2096-1413)
  
• Editorial board member for Chinese Medical Journal (ISSN: 0366-6999)
  
• Editorial board member for iLiver (ISSN: 2772-9478)
  
• Editorial board member for Intelligent Medicine (ISSN: 2667-1026)
  
• Editorial board member for HBPD INT (ISSN 1499-3872)

Grant History/Activity（selected）

1. National Key Research and Development Program of China: Research and Development, Industrialization and Promotion of Key Technologies of Multi-Mode Imaging Guided Intracavity Pulsed Electric Field Ablation System. Grant code: 2023YFF0713700. ￥1200,0000. 2023-2026.

2. National Natural Science Foundation of China (NSFC) Project: Research on Development Strategy of National Magnetic Medicine. Grant code: T2241008. ￥10,0000. 2022-2023.

3. Major Research Plan of the National Natural Science Foundation of China: Research on Key Technologies of Magnetic Navigation Endotracheal Intubation Robot. Grant Code: 92048202. ￥240,0000.2021-2024.

4. National Natural Science Foundation of China (NSFC) Major Development Project of Scientific Instrument: Development of Electromagnetic-Acoustic-Light Coupled Non-Invasive Steep Pulsed Electric Field Ablation System for Early Digestive Tract Cancer. Grant Code: 2018YFC0115300. ￥473,0000.2018-2021.

5. National Natural Science Foundation of China (NSFC) Project: Development of ERCP Combined With High-Voltage Pulsed Electric Field Minimally Invasive Precision Treatment Workstation for Hepatobiliary and Pancreatic Tumors. Grant Code: 81727802. ￥894,5700.2018-2022.

6. National Natural Science Foundation of China (NSFC) Project: The Impact of Magnamosis Rapid-Implantation of Donor Liver on the Imbalance of Intestinal Mucosal immunity and Gut microflora During Perioperation of Liver Transplantation. Grant code: 81470896. ￥840,000. 2015-2018.

7. Development Plan of Innovation Team of Ministry of Education of China: Abdominal surgery research on key technologies of medical combined with engineering. Grant code: IRT1279. ￥3,000,000. 2013-2015.

8. National Natural Science Foundation of China (NSFC) Scientific Instrument Foundation Project: Dispersed magnetic anchor intra-abdominal robots system. Grant code: 81127005/H0322. ￥2,800,000. 2012-2015.

9. National Natural Science Foundation of China (NSFC) Key Project: The foundation research of nano-degrade magnetic anastomosis for bile duct and vascular. Grant code: 30830099. ￥1,700,000. 2009-2012.

10. National Natural Science Foundation of China (NSFC) Project: Experimental study of recombinant TAT (Ant) -apoptin fusion protein in the treatment of liver cancer. Grant code: 30672069. ￥400,000. 2007-2009.

11. Ph.D. Programs Foundation of Ministry of Education of China: The key technique of cellular spleen as a liver stent. Grant code: 20110201130009. ￥400,000. 2012-2014.

12. Ministry of Health directly subordinate Hospital Key Project. DIPS and RPD using a magnetic squeeze technique and hybrid operations construction. Grant code: 2010105. ￥4,000,000. 2011-2012.

Awards

1. Second Prize of National Teaching Achievement Award: Clinical Traction, Knowledge Reconstruction, Model Innovation, and the Creation and Practice of a Cross-Medical And Engineering Graduate Training System, 2022.

2. The First Prize of Chinese Medical and Technology Award: Serial Research on Application of Strong Magnetic Biological Effect of Rare Earth NdFeB in Innovative Repair and Reconstruction of Digestive Surgery,2018

3. Baogang Outstanding Teacher Special Award Nomination Award,2018

4. Second prize of The Science and Technology Award of CACA. Invasion and metastasis mechanism of biliary and pancreatic tumors and innovation of key techniques for surgical treatment,2018

5. Second prize of National Award for Science and Technology Progress: Theoretical investigation and technical innovation of inflammation and damage control improved surgical outcomes of liver cancer, 2016

6. First prize of the Ministry of Education Technology Invention Award: The Establishment and Clinical Application of Choledochojejunostomy with Magnetic Compress Anastomosis, 2015

Selected Patents

1. Yi Lyu, Xiaopeng Yan，Shanpei Wang，et al. Magnetic Vascular Anastomosis Device for Rapid Liver Transplantation; 2023, US11596407B2.

2. Yi Lyu, Liyu Shan, Feng Ma, et al. The magnetic and wheat-mango bionic dual-drive device of capsule endoscope;2022, ZL201810389367.5

3. Feng Ma, Yi Lyu, Yanying Du, et al. Magnet and wheat-mango bionic dual-drive reverse intestinal flora transplanting device. 2021, ZL 201810389428.8

4. Yi Lyu, Xuemin Liu, Feng Ma, High-position magnetic biliary-enteric anastomosis device;2021, CN201910504324.1

5. Yi Lyu, Liangshuo Hu, Zhongquan Gao, et al. Balloon electrode catheter for cavity tissue ablation;2021, ZL201910936126.2.

6. Yi lyu, Yanying Du, Feng Ma, et al. Magnet and 'wheat and mango' bionic combined power down reverse colon examination device;2021, ZL 201810389429.2

7. Yi Lyu, Liyu Shan, Yanying Du, et al. Bionical driven alimentary canal magnetism anastomosis device of wheat mango;2021, ZL201810389425.4

8. Xiaopeng Yan, Yi Lyu, Feng Ma, et al. Magnetic anchoring puncture assembly for endoscopic lower gastrointestinal anastomosis; 2020, ZL 201811172739.5

9. Xiaopeng Yan, Yi Lyu, Feng Ma, et al. Magnetic anchoring system with electromagnetic control built-in grasper clutch for laparoscopic surgery;2020, ZL201710963102.7

10. Yi Lyu, Yu Luo, Xia Xin, et al. A kind of intelligent sputum aspirator;2018, ZL 201610322017.8

Selected Journal Publications

1. Liu Kang, Yang Hang, Huang Gaobo, Shi Aihua, Lu Qiang, Wang Shanpei, Qiao Wei, Wang Haohua, Ke Mengyun, Ding Hongfan, Li Tao, Zhang Yanchao, Yu Jiawei, Ren Bingyi, Wang Rongfeng, Wang Kailing, Feng Hui, Suo Zhigng*, Tang Jingda*, Lv Yi*. Adhesive anastomosis for organ transplantation[J]]. Bioactive Materials , 2021.11.003.(IF= 18.9)

2. Li Y, Zhang N, Lv Y, Third Int Conf Magnetic Surg. Expert consensus on magnetic recanalization technique for biliary anastomotic strictures after liver transplantation. HEPATOBILIARY SURGERY AND NUTRITION.2021,10(3):401-404.(IF=8)

3. Dong Jian *, Ke Meng-Yun *, Wu Xiao-Ning *,Ding Hong-Fan *, Zhang, Li-Na, Ma Feng, Liu Xue-Min,Wang Bo, Liu, Jian-Lin, Lu Shao-Ying, Wu Rongqian, Pawlik Timothy M.,Lyu Yi*, Zhang, Xu-Feng*. SRY is a key mediator of sexual dimorphism in hepatic ischemia/reperfusion injury[J]]. Annals of Surgery. 2022, 276(2): 345-356.(IF=10.1,Q1,Cited:7)

4. Zhang XG, Liu XM, Wang SP, Lu Q, Shi AH, Li Y, Qian YR, Liu K, Ma F, Wang HH, Li YL, Wu RQ, Zhang XF, Wang B, Lv Y*. Fast Vascular Reconstruction With Magnetic Devices in Liver Transplant: A Novel Surgical Technique. Liver Transplantation. 2021,27(2):286-290. (IF=5,Q1, Cited:3)

5. Lv Y*, Shi Y, Wang B, Li JH, Bai JG, Wu RQ, Liu SQ, Yan XP, Zhang X, Zhang XF, Liu XM, Graves CE, Co CS, Uygun I, Toselli L, Zaritzky MF, Fass TH, Cheng T, Zablotskii V, Sci Comm First Int Conf M. Xi'an consensus on magnetic surgery. Hepatobiliary Surgery and Nutrition, 2019,8(2):177-178. (IF=8, Cited: 26)

6. Lyu Y*. Recommendations and best practices in the field of magnetic surgery. Chinese Medical Journal. 2020,133(16):1981-1982. (IF=6.1, Cited: 2)

7. Jia P, Dong L, Yang X, Wang B, Bush SJ, Wang T, Lin J, Wang S, Zhao X, Xu T, Che Y, Dang N, Ren L, Zhang Y, Wang X, Liang F, Wang Y, Ruan J, Xia H, Zheng Y, Shi L, Lv Y*, Wang J*, Ye K*. Haplotype-resolved assemblies and variant benchmark of a Chinese Quartet. Genome Biol. 2023, 24(1):277.(IF=12.3 Cited:2)

8. Yan B, Liu C, Li H, Wen N, Jiao W, Wang S, Zhang Y, Zhang T, Zhang H, Lv Y*, Fan H*, Liu X*. Reversal of HMGA1-Mediated Immunosuppression Synergizes with Immunogenic Magnetothermodynamic for Improved Hepatocellular Carcinoma Therapy. ACS Nano. 2023,17(10):9209-9223.(IF=17.1 )

9. Liu XM, Li Y, Xiang JX, Ma F, Lu Q, Guo YG, Yan XP, Wang B, Zhang XF, Lv Y*. Magnetic compression anastomosis for biliojejunostomy and pancreaticojejunostomy in Whipple's procedure: An initial clinical study. J Gastroenterol Hepatol. 2019,34(3):589-594.(IF=4.1 Cited:18)

10. Ke MY, Fang Y, Cai H, Lu JW, Yang L, Wang Y, Wu RQ, Zhang XF, Lv Y*, Dong J*. The m6A reader YTHDF1 attenuates fulminant hepatitis via MFG-E8 translation in an m6A dependent manner. Int J Biol Sci. 2023,19(12):3987-4003. (IF=9.2)

11. Jia Y, Feng J, Feng Z, Liu J, Yang Y, Li X, Lei M, Guo H, Wei Z*, Lv Y*, Xu F*. An endoscopically compatible fast-gelation powder forms Janus-adhesive hydrogel barrier to prevent postoperative adhesions. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2219024120. (IF=11.1)

12. Li QS, Wang Y, Ma T, Ren FG, Mu F, Wu RQ, Lv Y*, Wang B*. Preoperative platelet count predicts posttransplant portal vein complications in orthotopic liver transplantation: a propensity score analysis. Bmc Gastroenterology. 2021,21(1). (IF=2.489)

13. Wang Y, Chen H, Tang B, Ma T, Li QS, Zhu HY, Zhang XG, Lv Y*, Dong DH*. Magnetic Spiderman, a New Surgical Training Device: Study of Safety and Educational Value in a Liver Transplantation Surgical Training Program. World Journal of Surgery. 2020,44(4):1062-1069. (IF=2.234)

14. Ren FG, Li QS, Hu LS, Yan XP, Gao ZY, Zhang J, Gao WM, Zhang Z, Chang PK, Chen X, Chu DK, Wu RQ, Lv Y*. Safety and efficacy of magnetic anchoring electrode-assisted irreversible electroporation for gastric tissue ablation. Surgical Endoscopy and Other Interventional Techniques. 2020,34(2):580-589. (IF=3.149)

15. Liu K, Huang GB, Chang PK, Zhang W, Li T, Dai ZJ, Lv Y*. Construction and validation of a nomogram for predicting cancer-specific survival in hepatocellular carcinoma patients. Scientific Reports. 2020,10(1). (IF=3.998)

16. Liao X, Bu Y, Xu ZH, Jia FG, Chang F, Liang JR, Jia QG*, Lv Y*. WISP1 Predicts Clinical Prognosis and Is Associated With Tumor Purity, Immunocyte Infiltration, and Macrophage M2 Polarization in Pan-Cancer. Frontiers in Genetics. 2020,11. (IF=3.258)

17. Li Y, Sun H, Yan XP, Wang SP, Dong DH, Liu XM, Wang B, Su MS, Lv Y*. Magnetic compression anastomosis for the treatment of benign biliary strictures: a clinical study from China. Surgical Endoscopy and Other Interventional Techniques.2020,34(6):2541-2550. (IF=3.149)

18. Li QS, Ren FG, Zhang YC, Chang PK, Wang Y, Ma T, Hu LS, Wu RQ, Wang B*, Lv Y*. Acute and subacute effects of irreversible electroporation on normal common bile ducts in a rabbit model. Journal of Hepato-Biliary-Pancreatic Sciences. 2020,27(10):776-784. (IF=4.16)

19. Lei H*, Pan Y, Wu RQ, Lv Y*. Innate Immune Regulation Under Magnetic Fields With Possible Mechanisms and Therapeutic Applications. Frontiers in Immunology. 2020;11. (IF=5.085)

20. Zhang X, Yuan Z, Wu JS, He Y, Lu GF, Zhang D, Zhao Y, Wu RQ, Lv Y, Cai KY, He SX. An Orally-Administered Nanotherapeutics with Carbon Monoxide Supplying for Inflammatory Bowel Disease Therapy by Scavenging Oxidative Stress and Restoring Gut Immune Homeostasis. ACS Nano 2023, 17(21):21116-21133. (IF=17.1)

21. Liu XF, Wang TX, Chen YL, Wang JT, Xie WJ, Wu RQ, Xu XT, Pang LH, Zhang XG, Lv Y, Wang GZ, Yamauchi Y, Jin T. Distinctive p-d orbital hybridization in RuSb nanobranches for simultaneously enhanced hydrogen evolution and hydrazine oxidation in alkaline seawater. Appl Catal B-Environ Energy 2023, 333: 122771. (IF=22.1)

22. Zhang XF, Xue F, Wu Z, Lopez-Aguiar AG, Poultsides G, Makris E, Rocha F, Kanji Z, Weber S, Fisher A, Fields R, Krasnick BA, Idrees K, Smith PM, Cho C, Beems M, Lyu Y, Maithel SK, Pawlik TM. Development and Validation of a Modified Eighth AJCC Staging System for Primary Pancreatic Neuroendocrine Tumors. Ann Surg 2022, 275(6):E773-E780. (IF=10.1)

23. Wei T, Zhang XF, He J, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Prognostic impact of perineural invasion in intrahepatic cholangiocarcinoma: multicentre study. Br J Surg 2022, 109(7):610-616. (IF=9.6)

24. Hu LS, Zhao Z, Mu F, Dong SY, Zhang C, Shi JH, Tian M, Guo K, Zhang XF, Yu L, Lv Y, Wang B. Utilization of elderly donors in liver transplantation for patients with hepatocellular carcinoma: A national retrospective cohort study of China. Int J Surg 2022, 105. (IF=15.3)

25. Chang L, Li YH, Li MX, Liu SB, Han JY, Zhao GX, Ji CC, Lyu Y, Genin GM, Bai BF, Xu F. An Injectable, biodegradable magnetic hydrogel system for exogenous promotion of muscle mass and regeneration. Chem Eng J 2021, 420. (IF=15.1)

26. Zhang XF, Xue F, Dong DH, Lopez-Aguiar AG, Poultsides G, Makris E, Rocha F, Kanji Z, Weber S, Fisher A, Fields R, Krasnick BA, Idrees K, Smith PM, Cho C, Beems M, Lv Y, Maithel SK, Pawlik TM. New Nodal Staging for Primary Pancreatic Neuroendocrine Tumors A Multi-institutional and National Data Analysis. Ann Surg 2021, 274(1):E28-E35. (IF=10.1)

27. Zhang XF, Xue F, Dong DH, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Number and Station of Lymph Node Metastasis After Curative-intent Resection of Intrahepatic Cholangiocarcinoma Impact Prognosis. Ann Surg 2021, 274(6):E1187-E1195. (IF=10.1 cited: 101, highly cited paper)

28. He JH, Zhang ZX, Yang YT, Ren FG, Li JP, Zhu SJ, Ma F, Wu RQ, Lv Y, He G, Guo BL, Chu DK. Injectable Self-Healing Adhesive pH-Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing. Nano-Micro Lett 2021, 13(1). (IF=26.6, cited:110, highly cited paper)

29. Li MX, Liu XM, Zhang XF, Zhang JF, Wang WL, Zhu Y, Dong J, Cheng JW, Liu ZW, Ma M, Lv Y*. Prognostic role of neutrophil- to- lymphocyte ratio in colorectal cancer: A systematic review and meta- analysis. Int J Cancer 2014, 134(10):2403-2413. (IF=6.4,cited:342, highly cited paper)

30 Bi JB, Zhang J, Ren YF, Du ZQ, Li QS, Wang Y, Wei SS, Yang LF, Zhang JY, Liu C, Lv Y, Wu RQ. Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress. Redox Biol 2019, 20:296-306. (IF=11.4, cited:158, highly cited paper)