Patrick Maisonneuve - Selected Publications#

Scopus H-index 112(563 documents, 43054 citations)
Google scholar H-index 134 (65,826 citations, i10-index 441)

Orecchia R, Veronesi U, Maisonneuve P, Galimberti VE, Lazzari R, Veronesi P, Jereczek-Fossa BA, Cattani F, Sangalli C, Luini A, Caldarella P, Venturino M, Sances D, Zurrida S, Viale G, Leonardi MC, Intra M. Intraoperative irradiation for early breast cancer (ELIOT): long-term recurrence and survival outcomes from a single-centre, randomised, phase 3 equivalence trial. Lancet Oncol 2021;22(5):597-608. (22 citations)

[These are results of a preplanned long-term follow-up of the Italian phase III ELIOT trial indicating a higher rate of ipsilateral breast tumor recurrence with partial breast irradiation using electron intraoperative radiotherapy vs postoperative whole-breast irradiation, with no difference in overall survival being observed.]

Hadjiliadis D, Khoruts A, Zauber AG, Hempstead SE, Maisonneuve P, Lowenfels AB; Cystic Fibrosis Colorectal Cancer Screening Task Force. Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations.
Gastroenterology 2018;154(3):736-45. (58 citations )

[These colorectal cancer screening recommendations developed under the auspice of the US Cystic Fibrosis foundation aim to help CF adults, families, primary care physicians, gastroenterologists, and CF transplantation centers address the issue of CRC screening. They differ from guidelines developed for the general population with respect to the recommended age of screening initiation, screening method, preparation, and the interval for repeat screening and surveillance.]

Milione M, Maisonneuve P, Spada F, Pellegrinelli A, Spaggiari P, Albarello L, Pisa E, Barberis M, Vanoli A, Buzzoni R, Pusceddu S, Concas L, Sessa F, Solcia E, Capella C, Fazio N, La Rosa S. The Clinicopathologic Heterogeneity of Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms: Morphological Differentiation and Proliferation Identify Different Prognostic Categories. Neuroendocrinology 2017;104(1):85-93. (133 citations)

[This retrospective study of patients affected by grade 3 GEP-NECs from 6 Italian institutions indicate that GEP-NECs represent a heterogeneous group of neoplasms which can be better classified in different prognostic categories using both tumor morphology and Ki-67 index]

Rampinelli C, De Marco P, Origgi D, Maisonneuve P, Casiraghi M, Veronesi G, Spaggiari L, Bellomi M. Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis. BMJ 2017;356:j347. (106 citations)

[In this report, we estimated the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT) in the COSMOS trial. Results indicate that radiation exposure and cancer risk, even if non-negligible, can be considered acceptable in light of the substantial mortality reduction associated with screening.]

Bruno S, Di Marco V, Iavarone M, Roffi L, Crosignani A, Calvaruso V, Aghemo A, Cabibbo G, Viganò M, Boccaccio V, Craxí A, Colombo M, Maisonneuve P. Survival of patients with HCV cirrhosis and sustained virologic response is similar to the general population. J Hepatol 2016;64(6):1217-23 (89 citations)

[Prospective surveillance of three cohorts of Italian patients with compensated HCV cirrhosis. Outcome of patients who achieved SVR on an interferon-based (IFN) regimen was compared to that of non-SVR, untreated and decompensated patients. This study demonstrated that achievement of SVR originates a major survival benefit, with a life expectancy similar to the general population.]

SELECTED LANDMARK PAPERS

Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, Intra M, Veronesi P, Robertson C, Maisonneuve P, Renne G, De Cicco C, De Lucia F, Gennari R. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer.
N Engl J Med 2003;349:546-53. (1671 citations)

[This highly cited single institution randomized trial demonstrated the capacity of the sentinel-node biopsy to predict the presence or absence of axillary nodes positive for metastasis. Based on this and other related evidence, the American Society of Clinical Oncology (ASCO) recommended SLNB in clinically cN0 early breast cancer]

Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet 2001;358(9285):861-5 (580 citations)

[This highly cited study pointed that a single measurement of low serum thyrotropin in individuals aged 60 years or older is associated with increased mortality from all causes, and in particular mortality due to circulatory and cardiovascular diseases.]

Maisonneuve P, Agodoa L, Gellert R, Stewart JH, Buccianti G, Lowenfels AB, Wolfe RA, Jones E, Disney AP, Briggs D, McCredie M, Boyle P. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet 1999;354(9173):93-9. (667 citations)

[This is one of the largest cohort study ever conducted assembling data from 831,804 patients with end-stage renal in three continents, allowing quantifying the risk of cancer and raising the question of the correct approach to cancer screening in ESRD patients.]

Neglia JP, FitzSimmons SC, Maisonneuve P, Schoni MH, Schoni-Affolter F, Corey M, Lowenfels AB. The risk of cancer among patients with cystic fibrosis. Cystic Fibrosis and Cancer Study Group. N Engl J Med 1995;332(8):494-9. (295 citations)

[First analysis of a large cohort study evaluating the risk of cancer in patients with cystic fibrosis. This and the subsequent reports form the same group identified an increased risk of digestive cancers in CF, leading to development of specific colon cancer screening guidelines for the CF population].

Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, Dimagno EP, Andren-Sandberg A, Domellof L.

Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med 1993;328(20):1433-7. (1472 citations)

[Highly cited seminal multicenter cohort study demonstrating an increased risk of pancreatic cancer in patients with pancreatitis]