Sergei A. Nedospasov - Selected publications#

Kulikov A.V., Shilov E.S., Mufazalov I.A., Gogvadze V., Nedospasov S.A., Zhivotovsky B. (2012) Cytochrome c: the Achilles' heel in apoptosis. Cell. Mol. Life Sci., 69 (11): 1787-1797.

Widenmeyer M., Shebzukhov Y., Haen S.P., Schmidt D., Clasen S., Boss A., Kuprash D.V., Nedospasov S.A., Stenzl A., Aebert H., Wernet D., Stevanovic S., Pereira P.L., Rammensee H.G., Gouttefangeas C. (2011) Analysis of tumor antigen-specific T cells and antibodies in cancer patients treated with radiofrequency ablation. International Journal of Cancer, 128 (11): 2653-2662.

Drutskaya M.S., Belousov P.V., Nedospasov S.A. (2011) Innate mechanisms of viral recognition. Molecular Biology, 45 (1): 5-15.

Tumanov A.V., Grivennikov S.I., Kruglov A.A., Shebzukhov Y.V., Koroleva E.P., Piao Y.L., Cui C.Y., Kuprash D.V., Nedospasov S.A. (2010) Cellular source and molecular form of TNF specify its distinct functions in organization of secondary lymphoid organs. Blood, 116 (18): 3456-3464.

Arbatsky N.P., Kondakova A.N., Shashkov A.S., Drutskaya M.S., Belousov P.V., Nedospasov S.A., Petrova M.A., Knirel Y.A. (2010) Structure of the O-polysaccharide of Acinetobacter sp VS-15 and Acinetobacter lwoffii EK67. Carbohydrate Research, 345 (15): 2287-2290.

Belousov P.V., Kuprash D.V., Nedospasov S.A., Shebzukhov Y.V. (2010) Autoantibodies to Tumor-Associated Antigens as Cancer Biomarkers. Current Molecular Medicine, 10 (2): 115-122.

Arbatsky N.P., Kondakova A.N., Shashkov A.S., Drutskaya M.S., Belousov P.V., Nedospasov S.A., Petrova M.A., Knirel Y.A. (2010) Structure of the O-antigen of Acinetobacter lwoffii EK30A; identification of D-homoserine, a novel non-sugar component of bacterial polysaccharides. Biomolecular Chemistry, 8 (15): 3571-3577.

Mufazalov I.A., Penkov D.N., Chernyak B.V., Pletjushkina O.Y., Vyssokikh M.Y., Chertkova R.V., Kirpichnikov M.P., Dolgikh D.A., Kruglov A.A., Kuprash D.V., Skulachev V.P., Nedospasov S.A. (2009) Preparation and characterization of mouse embryonic fibroblasts with K72W mutation in somatic cytochrome C gene. Molecular Biology, 43 (4): 596-603.

Galimov A.R., Kruglov A.A., Bolsheva N.L., Yurkevich O.Y., Liepinsh D.J., Mufazalov I.A., Kuprash D.V., Nedospasov S.A. (2008) Chromosomal localization and molecular organization of the human genomic fragment containing the TNF/LT locus in transgenic mice. Molecular Biology, 42 (4): 558-566.

Heikenwalder M., Prinz M., Zeller N., Lang K.S., Junt T., Rossi S., Tumanov A., Schmidt H., Priller J., Flatz L., Rulicke T., Macpherson A.J., Hollander G.A., Nedospasov S.A., Aguzzi A. (2008) Overexpression of lymphotoxin in T cells induces fulminant thymic involution. American Journal of Pathology, 172 (6): 1555-1570.

Kruglov A.A., Kuchmiy A., Grivennikov S.I., Tumanov A.V., Kuprash D.V., Nedospasov S.A. (2008) Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: Mouse models. Growth Factor Reviews, 19 (3): 231-244.

Shebzukhov Y.V., Lavrik I.N., Karbach J., Khlgatian S.V., Koroleva E.P., Belousov P.V., Kashkin K.N., Knuth A., Jager E., Chi N.W., Kuprash D.V., Nedospasov S.A. (2008) Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients. Cancer Immunology Immunotherapy, 57 (6): 871-881.

Belousov P.V., Kuprash D.V., Sazykin A.Y., Khlgatian S.V., Penkov D.N., Shebzukhov Y.V., Nedospasov S.A. (2008) Cancer-associated antigens and antigen arrays in serological diagnostics of malignant tumors. Biochemistry-Moscow, 73 (5): 562-572.

Shebzukhov Y.V., Koroleva E.P., Khlgatian S.V., Belousov P.V., Sazykin A.Y., Kadachigova T.S., Pomerantseva E.A., Lagarkova M.A., Nedospasov S.A., Kuprash D.V. (2007) RAP80/UIMC1 as cancer-associated antigen: Alternative splice variants and their immunogenicity. Cancer Letters, 255 (2): 255-262.

Nedospasov S.A., Kuprash D.V. (2007) Oncoimmunology: Some fundamental problems of cancer immunotherapy. Molecular Biology, 41 (2): 316-328.

Kashkin K.N., Khlgatian S.V., Gurova O.V., Kuprash D.V., Nedospasov S.A. (2007) New mutations in the human p53 gene a regulator of the cell cycle and carcinogenesis. Biochemistry-Moscow, 72 (3): 282-292.

Shebzukhov Y.V., Koroleva E.P., Khlgatian S.V., Belousov P.V., Kuz'mina K.E., Radko B.V., Longpre F., Lagarkova M.A., Kadachigova T.S., Gurova O.V., Meshcheryakov A.A., Lichinitser M.R., Knuth A., Jager E., Kuprash D.V., Nedospasov S.A. (2005) Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients. International Journal of Cancer, 117 (5): 800-806.

Shebzukhov Y.V., Koroleva E.P., Khlgatian S.V., Lagarkova M.A., Meshcheryakov A.A., Lichinitser M.R., Karbach J., Jager E., Kuprash D.V., Nedospasov S.A. (2005) Humoral immune response to thymidylate synthase in colon cancer patients after 5-FU chemotherapy. Immunology Letters, 100 (1): 88-93.

Grivennikov S.I., Tumanov A.V., Liepinsh D.J., Kruglov A.A., Marakusha B.I., Shakhov A.N., Murakami T., Drutskaya L.N., Forster I., Clausen B.E., Tessarollo L., Ryffel B., Kuprash D.V., Nedospasov S.A. (2005) Distinct and nonredundant in vivo functions of TNF produced by T cells and macrophages/neutrophils: Protective and deleterious effects. Immunity, 22 (1): 93-104.

Koroleva E.P., Lagarkova M.A., Khlgatian S.V., Shebzukhov Y.V., Mescheryakov A.A., Lichinitser M.R., Nedospasov S.A., Kuprash D.V. (2004) Serological analysis of the repertoire of human cancer antigens and autoantigens. Molecular Biology, 38 (2): 191-195.

Abe K., Yarovinsky F.O., Murakami T., Shakhov A.N., Tumanov A.V., Ito D., Drutskaya L.N., Pfeffer K., Kuprash D.V., Komschlies K.L., Nedospasov S.A. (2003) Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo. Blood, 101 (4): 1477-1483.

Lagarkova M.A., Koroleva E.P., Kuprash D.V., Boitchenko V.E., Kashkarova U.A., Nedospasov S.A., Shebzukhov Y.V. (2003) Evaluation of humoral response to tumor antigens using recombinant expression-based serological mini-arrays (SMARTA). Immunology Letters, 85 (1): 71-74.

Kuprash D.V., Alimzhanov M.B., Tumanov A.V., Grivennikov S.I., Shakhov A.N., Drutskaya L.N., Marino M.W., Turetskaya R.L., Anderson A.O., Rajewsky K., Pfeffer M., Nedospasov S.A. (2002) Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: Mice with inactivation of the entire TNF/LT locus versus single-knockout mice. Molecular and Cellular Biology, 22 (24): 8626-8634.

Kuprash D.V., Boitchenko V.E., Yarovinsky F.O., Rice N.R., Nordheim A., Ruhlmann A., Nedospasov S.A. (2002) Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells. Blood, 100 (5): 1721-1727.

Tumanov A.V., Kuprash D.V., Lagarkova M.A., Grivennikov S.I., Abe K., Shakhov A.N., Drutskaya L.N., Stewart C.L., Chervonsky A.V., Nedospasov S.A. (2002) Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity, 17 (3): 239-250.

Hehlgans T., Stoelcker B., Stopfer P., Muller P., Cernaianu G., Guba M., Steinbauer M., Nedospasov S.A., Pfeffer K., Mannel D.N. (2002) Lymphotoxin-beta receptor immune interaction promotes tumor growth by inducing angiogenesis. Cancer Research, 62 (14): 4034-4040.

Aliev T.K., Panina A.A., Radko B.V., Petrovskaya L.E., Shingarova L.N., Nedospasov S.A., Zav'yalova G.A., Korobko V.G., Zav'yalov V.P. (2002) Design and expression of humanized monoclonal antibody f10 that neutralizes human tumor necrosis factor-alpha. Clinical Immunology, 103 (3): S90-S91.

Shakhov A.N., Nedospasov S.A. (2001) Expression profiling in knockout mice: lymphotoxin versus tumor necrosis factor in the maintenance of splenic microarchitecture. Growth Factor Reviews, 12 (1): 107-119.

Drutskaya M.S., Kuprash D.V., Nedospasov S.A., Chertkov I.L., Drize N.I. (2001) Abnormal hemopoiesis in long-term bone marrow culture from tumor necrosis factor-deficient mice. Bulletin of Experimental Biology and Medicine, 131 (2): 150-152.

Kuimov A.N., Kuprash D.V., Petrov V.N., Vdovichenko K.K., Scanlan M.J., Jongeneel C.V., Lagarkova M.A., Nedospasov S.A. (2001) Cloning and characterization of TNKL, a member of tankyrase gene family. Genes and Immunity, 2 (1): 52-55.