Mary Anne O'Connell - Selected Publications#

Khan A, S Paro, L McGurk, N Sambrani, MC Hogg, J Brindle, G Pennetta, LP Keegan, and MA O'Connell. (2020) Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy. BMC Biol. 18(1):15. doi: 10.1186/s12915-020-0747-0.

Tan TY, J. Sedmík, MP Fitzgerald, RS Halevy, LP Keegan, I Helbig, L Basel-Salmon, L Cohen, R Straussberg, WK Chung, M Helal, R Maroofian, H Houlden, J Juusola, S Sadedin, L Pais, KB Howell, SM White, J Christodoulou, MA O'Connell (2020) Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures. Am J Hum Genet. pii: S0002-9297(20)30057-4. doi: 10.1016/j.ajhg.2020.02.015.

Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, Pollina EA, Leeman DS, Rustighi A, Goh YPS; ...........Chawla A, Del Sal G, Peltz G, Brunet A, Conrad DF, Samuel CE, O'Connell MA, Walkley CR, Nishikura K, Li JB. 2017 Dynamic landscape and regulation of RNA editing in mammals. Nature. 550(7675):249-254.

Mannion, N.M., S. M. Greenwood R. Young, S. Cox, J. Brindle, D. Read, C. Nellåker, C. Vesely, C. Ponting, M. F. Jantsch, J. Dorin, I. R. Adams, M. Öhman, L. P. Keegan and M. A. O’Connell. 2014. The RNA editing enzyme ADAR1 is a key component of innate immune responses to RNA. Cell Reports 9(4):1482-9

Heale, B.S.E., L. P. Keegan, L. McGurk, G. Michlewski, J. Brindle, C. M. Stanton, J. F. Caceres, and M. A. O’Connell. 2009. Editing independent effects of ADARs on the miRNA/siRNA pathways. EMBO J.;28(20):3145-56. Epub 2009 Aug 27

Gallo A, L. P. Keegan, G. M. Ring and M. A. O'Connell 2003 An ADAR that edits transcripts encoding ion channel subunits functions as a dimer. EMBO J.22 (13) 3421-30.

Palladino M. J., L. P. Keegan, M. A. O'Connell, and R. A. Reenan. 2000 A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity. Cell 102 (4) 437-49.

O'Connell, M. A., A. Gerber and W. Keller. 1997. Purification of human double-stranded RNA-specific editase1 (hRed1), involved in editing of brain glutamate receptor B pre-mRNA. J. Biol. Chem. 272 473-478.

O'Connell, M. A., S. Krause, M. Higuchi, J.J. Hsuan, N. Totty, A. Jenny, and W. Keller. 1995. Cloning of cDNAs encoding double-stranded RNA-specific adenosine deaminase. MCB, 15, 1389-1397.

O'Connell, M. A., and W. Keller. 1994. Purification and properties of double-stranded RNA-specific adenosine deaminase from calf thymus. PNAS, 91, 10596-10601.

H-index 31 (Web of Science), citations 4076 (Web of Science).