Maria Gabriella Santoro - Publications#

MGS is an author of 3 books, more than 120 publications as first-or-last author in peer-reviewed international journals in cell biology and biochemistry, cancer biology and virology (Bibliographic indices: H-index 48, Total citations >10.000; Google Scholar), and an inventor of more than 10 international patents granted in the US, Canada and Europe.

Publication list
PATENT list

List of 10 selected publications:

1. Santopolo S, Riccio A, Rossi A and Santoro MG. The proteostasis guardian HSF1 directs the transcription of its paralog and interactor HSF2 during proteasome dysfunction. Cell. Mol. Life Sci. 78: 1113–1129, 2021.

2. Pizzato Scomazzon S, Riccio A, Santopolo S, Lanzilli G, Coccia M, Rossi A and Santoro MG. The Zinc-finger AN1-type domain 2a gene acts as a regulator of cell survival in human melanoma: role of E3-Ligase cIAP2. Molecular Cancer Research 17: 2444-2456, 2019.

3. Piacentini S, La Frazia S, Riccio A, Pedersen J, Topai A, Nicolotti O, Rossignol JF and Santoro MG. Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57. Scientific Reports, 8: 10425, 2018. doi: 10.1038/s41598-018-28172-9.

4. Coccia M, Rossi A, Riccio A, Trotta E and Santoro MG. Human NF-kB Repressing Factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance. P.N.A.S. USA, 114: 1045-1050, 2017.

5. Rossi A, Riccio A, Coccia M, Trotta E, La Frazia S and Santoro MG. The proteasome inhibitor bortezomib is a potent inducer of zinc-finger AN1-type domain 2a gene expression: role of HSF1/HSF2 heterocomplexes. J. Biol. Chem. 289: 12705-12715, 2014.

6. La Frazia S, Ciucci A, Arnoldi F, Coira, M, Gianferretti, P, Angelini M, Belardo G, Burrone O, Rossignol J and Santoro MG. Thiazolides, a new class of antiviral agents effective against rotavirus infection, target viral morphogenesis inhibiting viroplasm formation. J. Virol. 87: 11096-11106, 2013.

7. Rossignol JF, La Frazia S, Chiappa L, Ciucci A and Santoro MG: Thiazolides, a new class of anti-influenza molecules targeting viral protein hemagglutinin at post-translational level. J. Biol. Chem. 284: 29798-29808, 2009.
8. Rossignol JF, Abu-ZekryM, Hussein A, Santoro MG. Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: randomised double-blind placebo-controlled trial. Lancet 368:124-129, 2006.

9. Santoro MG, Rossi A and Amici C. NF-kB and virus infection: who controls whom. EMBO J. 22: 2552-2560, 2003..

10. Rossi A, Kapahi P, Natoli G, Takahashi T, Karin M and Santoro MG. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkB kinase (IKK). Nature, 403: 103-108, 2000.