Dionysia Theodosis - Research #

Dionysia Thodosis' major scientific interest has always revolved around the cell biology and morphology of the central nervous system. Initially trained as an electron microscopist, that vision of the natural world has continued to attract and fascinate her. Her work still revolves around a discovery she made about 20 years ago, namely, that the structure of the adult brain is not fixed but can be modified in response to purely physiological conditions. In the female brain, this is exemplified by maternity, which results in profound changes in the morphology of oxytocin neurons, their supportive cells, the astroglia, and the synapses that drive their activity. These changes are reversible and the part of the hypothalamus that undergoes such plasticity reverts to its 'virgin' condition once maternity is over; it will be reorganised in the course of another maternal period. Presently, her laboratory is active in the study of the cellular and molecular bases underlying this kind of neuronal plasticity.

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