Alfred Wittinghofer - Curriculum Vitae#

• born in Goch, Kreis Kleve, Germany, 23.5.1943
• son of Josef and Else Wittinghofer
• married to Uschi Wittinghofer, father of two sons, Pan and Henk
• Easter 1963: Abitur at the Friedrich-Spee-Gymnasium Geldern
• 1962-1968: Study of Chemistry at the Technische Hochschule Aachen, Germany
• June 1968: Diploma
• Diploma work and Doctoral thesis at the German Wool Research Institute in Aachen, subject: total chemical synthesis of insulin
• March 1971: Ph.D
• 1971-1973: postdoctoral fellow with Prof. R.G. Hiskey at the University of North Carolina, subject: modification of proteins
• Since 1974 scientific assistant at the Max-Planck-Institut für medizinische Forschung, Heidelberg, Germany
• Since 1980 head of an own research group: Studies on structure/function of EF-Tu, adenylate kinase, myosin heavy chain and the oncogene product Ras, biology of the Ras gene, interaction of Ras with regulators and effectors, studies on Ran regulated nuclear transport
• 1992: Habilitation, University Heidelberg, Germany. Habilitation for Biochemistry at the Faculty of Medicine, University Heidelberg
• 1993 – June 2009 Director of the Department ‘Structural Biology’ at the Max-Planck-Institute of Molecular Physiology, Dortmund, Germany General subject: GTP-binding proteins in cell biology
• Honorarprofessor for Biochemistry at the Faculty of Chemistry Ruhr-University Bochum, Germany
• Since July 2009 Emeritus Group at the Max-Planck-Institute of Molecular Physiology, Dortmund, Germany

• Louis-Jeantet Prize for Medicine 2001
• Richard-Kuhn-Medal of the Gesellschaft Deutscher Chemiker (GDCh), 2002
• Deutscher Krebspreis 2003 der Deutschen Krebsgesellschaft e.V.
• Otto-Warburg-Medal of the GBM, 2003

• Nathan O. Kaplan Memorial Lecture, University of California, San Diego, 1997
• Felix Hoppe-Seyler Lecturer 1998
• Rudolf Virchow-Lecture, Medizinische Fakultät der Universität Würzburg, 2002
• Otto-Warburg-Chemie Lecture, Otto-Warburg-Chemie-Foundation, University Bayreuth, 2004
• Keynote lecture FASEB Summer Research Conference: Regulation and Function small GTPases, Saxton River 2008
• Director Lecture, Sloan Kettering Comprehensive Cancer Center New York, 2008
• NIH Director’s Lecture, U.S. Department of Health and Human Services, 2009
• Keynote lecture: Conference Jacques-Monod, Regulation and Function of small GTPaases, Aussois 2009
• Keynote Lecture Eurotox 2009, Dresden

• EMBO Member
• Member of the Academia Europaea
• Senator Section Biochemistry/Biophysik of the Deutsche Akademie der Naturforscher Leopoldina
• Member of the Nordrhein-Westfälische Akademie der Wissenschaften, Class for Naturwissenschaften und Medizin
• Honorary Member of the Japanese Biochemical Society
• Fellow of the European Academy of Cancer Sciences, since 2009