Esteban Domingo - Curriculum vitae#

Present position:

Ad Honorem (Emeritus) Professor of Research at the Spanish Research Council (CSIC).

Education:

B.Sc. in Chemistry at the University of Barcelona (1965). Ph.D. in Biochemistry, University of Barcelona (1969). Maximum grades: “Premio Extraordinario” for B.Sc. (1965) and for Ph.D. (1969).

Postdoctoral experience:

• Oct. 1969-Dec. 1973: With Prof. Robert C. Warner, Department of Molecular Biology and Biochemistry, University of California at Irvine, California (USA). In vitro transcription.
• Jan. 1974-July 1976: With Prof. Charles Weissmann, Institut für Molekularbiologie I, Universitat Zürich, 8093 Zürich (Switzerland). Genetics of phage Qβ.

Visits to other laboratories and sabbaticals:

• 1980-81: BIOGEN S.A. (Switzerland). Molecular cloning and gene expression.
• August 1983: National Institute for Medical Research, Mil Hill, London (UK), with Dr. J. Skehel. Dideoxy sequencing of influenza virus genes.
• August 1988 - August 1989: Sabbatical year at the Univ. of California, San Diego (USA), with Dr. J. Holland. RNA virus heterogeneity.
• Jan. 1991 - April 1991: Additional visit at UCSD, with Dr. J. Holland. RNA virus heterogeneity.
• Oct. 1999 – Nov. 1999: Scripps Research Institute, with Drs. M.B.A. Oldstone and J.C. de la Torre. Genetics of lymphocytic choriomeningitis virus.

Membership:

• Editorial board of: Microbiologia S.E.M. (since 1985) / Virus Research (since 1987) / J. Gen. Virology (1988-1993; and since 2003) / J. Virol. (since 1995) / Viral Immunology (1994-1999) / Archives in Virology (since 1997) / Virologie (France) (since 1997) / AIDS Reviews (1999-2003) / Virology (since 2002)/ Associate editor, PLoS Pathogens (since 2008)
• Editor of J.Gen.Virol. (1998-2002)
• Spanish representative in the Standing Technical Committee of FAO on FMD research (1986-1992)
• Member of the Advisory Committee of the Division of Virology of the International Union of Microbiological Societies (IUMS) (1999-2005)
• Founder member and scientific board member of Institute Para Limes, The Netherlands (since 2006)
• President of the Spanish Society for Virology (since 2007)
• Editor of Virus Research (since 2012)

Teaching:

At the Univ. Calif. Irvine (1971-73) and Univ. Autónoma de Madrid (Spain) 1978-1992 / Director of "Master in Biotechnology" given at the CBMSO (1992-1993), and coordinator (1994-1995). Professor at the “Cours de Virologie Fondamentale”, Institut Pasteur, Paris, France (since 1993). Professor at the course “Genetics and Evolution of Viruses”(since 2003), Univ. of Helsinki, Finland. Organizer: Dr. A. Plyusnin.

Director or co-director of 22 Doctoral Theses.

Publications:

360 papers in international journals and books; H index=69 (December 2013). Author or editor of 5 books. Main scientific achievements: Demonstration of high mutation rates and quasispecies dynamics of RNA viruses. Establishment of cell lines persistently infected with foot-and-mouth disease virus. Lethal mutagenesis as a new antiviral strategy.

Main scientific interests:

Biological implications of quasispecies dynamics. Molecular basis of virus extinction by enhanced mutagenesis. Antiviral activity of nucleoside analogues.

Main scientific distinctions:

• Member of the EMBO (since 1991)
• Honorary Member of the European Society for Veterinary Virology (since 1997)
• Member of the European Academy (since 1998)
• Doctor Honoris causa from the Université de Liège, Belgium (1999)
• Doctor Honoris causa from the University of Bern, Switzerland (2004)
• Premio Cultura Viva (2010)
• Member of Real Academia de Ciencias Exactas, Físicas y Naturales, from the Natural Sciences Section (since 2012)