Bernhard Fleckenstein - Selected publications#

• Fleckenstein, B., Daniel, M.D., Hunt, R.D., Werner, F.-J., Falk, L.A., and Mulder, C. (1978). Tumor induction with DNA of oncogenic primate herpesviruses. Nature 274, 57-59.

• Desrosiers, R.C., Mulder, C., and Fleckenstein, B. (1979). Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines.Proc. Natl. Acad. Sci., USA 76, 3839-3843.

• Boshart, M., Weber, F., Jahn, G., Dorsch-Häsler, K., Fleckenstein, B., and Schaffner, W. (1985). A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41, 521-530.

• Hennighausen, L. and Fleckenstein, B. (1986). Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene. EMBO J. 5, 1367-1371.

• Grassmann, R., Dengler, C., Müller-Fleckenstein, I., Fleckenstein, B., McGuire, K., Dokhelar, M.-C., Sodroski, J., and Haseltine, W.A. (1989). Transformation to continous growth of primary human lymphocytes by HTLV-1 X region genes transduced by a Herpesvirus saimiri vector. Proc. Natl. Acad. Sci. 86, 3351-3355.

• Mittrücker, H.-W., Müller-Fleckenstein, I., Fleckenstein, B., and Fleischer, B. (1992). CD2-mediated autocrine growth of herpesvirus-saimiri-transformed human T lymphocytes. J. Exp. Med. 176, 909-913

• Weber, F., Meinl, E., Drexler, K., Czlonkowska, A., Huber, S., Fickenscher, H., Müller-Fleckenstein, I., Fleckenstein, B., Wekerle, H., and Hohlfeld, R. (1993). Transformation of human T cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells. Proc. Natl. Acad. Sciences, USA 90, 11049-11053.

• Swanton, C., Mann, D.J., Fleckenstein, B., Neipel, F., Peters, G. and Jones, N. (1997). Herpes viral cyclin/cdk6 complexes evade inhibition by cdk inhibitor proteins. Nature 390, 184-187.

• Ensser, A., Glykofrydes, D., Niphuis, H., Kuhn, E.M., Rosenwirth, B., Heeney, J.L., Bruder, J., Niedobitek, G., Müller Fleckenstein, I., and Fleckenstein, B. (2001). Independence of herpesvirus induced T-cell lymphoma from viral cyclinD homologue. J. Exp. Med. 193, 637-642.

• Ensser, A. and Fleckenstein, B. (2005). T-Cell Transformation and Oncogenesis by gamma-2-Herpesviruses. Adv.Cancer.Res. 93, 91-128.

• Jung, S., Eichenmüller, M., Donhauser, N., Neipel, F., Engel, A. M., Hess, G., Fleckenstein, B., and Reil, H. (2007). HIV entry inhibition by the envelope 2 glycoprotein of GB virus C. AIDS 21, 645-647.

• Hahn, A., Kaufmann, J. K., Wies, E., Naschberger, E., Panteleev-Ivlev, J., Schmidt, K., Holzer, A., Schmidt, M., Chen, J., König, S., Ensser, A., Myoung, J., Brockmeyer, N. H., Stürzl, M., Fleckenstein, B., and Neipel, F. (2012). The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma-associated herpesvirus. Nature Medicine 18, 961–966.