Javier García-Sancho - Publications#
Over 190 scientific papers. H index, 45.
Recent examples:
VILLALOBOS, C., NUÑEZ, L., MONTERO, M. GARCÍA, A.G., ALONSO, M.T., CHAMERO, P., ALVAREZ, J. & GARCÍA-SANCHO, J. (2002) Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells. FASEB J., 16: 343-353
CHAMERO, P., VILLALOBOS, C. ALONSO, M.T.&d GARCÍA-SANCHO, J. (2002) Dampening of cytosolic Ca2+ oscillations on propagation to nucleus in pituitary cells. J. Biol. Chem. 277: 50226-50229
FERNANDEZ-AVILES F, SAN ROMAN JA, GARCIA-FRADE J, FERNANDEZ ME, PENARRUBIA MJ, DE LA FUENTE L, GOMEZ-BUENO M, CANTALAPIEDRA A, FERNANDEZ J, GUTIERREZ O, SANCHEZ PL, HERNANDEZ C, SANZ R, GARCIA-SANCHO J, & SANCHEZ A.(2004) Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction. Circ Res. 95:742-8.
SENOVILLA L, NUNEZ L, DE CAMPOS JM, DE LUIS DA, ROMERO E, SANCHEZ A, GARCIA-SANCHO J & VILLALOBOS C. (2004) Multifunctional cells in human pituitary adenomas: implications for paradoxical secretion and tumorigenesis. J Clin Endocrinol Metab. 89:4545-52.
SENOVILLA L, GARCIA-SANCHO J & VILLALOBOS C. (2005) Changes in expression of hypothalamic releasing hormone receptors in individual rat anterior pituitary cells during maturation, puberty and senescence. Endocrinology 146: 4627-4634.
VILLALOBOS C, NADAL A, NUNEZ L, QUESADA I, CHAMERO P, ALONSO MT & GARCIA-SANCHO J. (2005) Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse. Cell Calcium 38:131-139
GARCIA, A.G. GARCIA-DE-DIEGO, A.M., GANDIA, L., BORGES, R. & GARCIA-SANCHO, J. (2006) Calcium Signaling and Exocytosis in Adrenal Chromaffin Cells. Physiol. Rev. 86: 1093-1131.
NÚÑEZ, L., SENOVILLA, L., VILLALOBOS, C., CHAMERO, P., ALONSO, M.T. & GARCÍA-SANCHO, J. (2007) Bioluminescence imaging of subcelular Ca2+ dynamics in soma and neurites from individual adult mouse sympathetic neurons. J. Physiol., 580: 385-395
SÁNCHEZ, A. & GARCÍA-SANCHO, J. (2007) Cardiac repair by stem cells. Cell Death and Differentiation, 14:1258-1261
MANJARRES I.M., CHAMERO P., DOMINGO B., MOLINA F., LLOPIS J., ALONSO M.T. & GARCIA-SANCHO J. (2008) Red and green aequorins for simultaneous monitoring of Ca2+ signals from two different organelles. Pflugers Arch. 455: 961-970
SENOVILLA, L., NÚÑEZ, L., VILLALOBOS, C. & GARCÍA-SANCHO, J. (2008) Rapid changes in anterior pituitary cell phenotypes in male and female mice after acute, cold stress. Endocrinology149: 2159-2167
CHAMERO, P., MANJARRES, I.M., GARCIA-VERDUGO, J.M., VILLALOBOS, C., ALONSO, M.T. & GARCÍA –SANCHO, J (2008) Nuclear calcium signaling by inositol trisphosphate in GH3 pituitary cells. Cell Calcium, 43: 205-214
GALLEGO-SANDÍN S, RODRÍGUEZ-GARCÍA A, ALONSO MT & GARCÍA-SANCHO J (2009) The endoplasmic reticulum of dorsal root ganglion neurons contains functionalTRPV1 channels. J Biol Chem., 284: 32591-32601
MANJARRÉS IM, RODRÍGUEZ-GARCÍA A, ALONSO MT & GARCÍA-SANCHO J. (2010) The sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) is the third element in capacitative calcium entry. Cell Calcium, 47: 412-418
ALONSO, MT & GARCÍA-SANCHO, J. (2011) Nuclear Ca2+ signalling. Cell Calcium, 49: 280-289
AULESTIA FJ, REDONDO PC, RODRIGUEZ-GARCIA A, ROSADO JA, SALIDO GM, ALONSO MT, GARCIA-SANCHO J. (2011) Two distinct calcium pools in the endoplasmic reticulum of HEK293T cells. Biochem J., 435: 227-235
CONDE DE FELIPE MM, FEIJOO REDONDO A, GARCÍA-SANCHO J, SCHIMMANG T, DURÁN ALONSO MB. (2011) Cell- and gene-therapy approaches to inner ear repair. Histol Histopathol. 26: 923-940.
MANJARRÉS IM, ALONSO MT, GARCÍA-SANCHO J. (2011) Calcium entry-calcium refilling (CECR) coupling between store-operated Ca(2+) entry and sarco/endoplasmic reticulum Ca(2+)-ATPase. Cell Calcium 49: 153-161.
GALLEGO-SANDÍN, S, ALONSO, M.T. & GARCÍA-SANCHO, J. (2011) Calcium homeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress. Biochem. J. 437: 469-475
OROZCO L, SOLER R, MORERA C, ALBERCA M, SÁNCHEZ A, GARCÍA-SANCHO J. (2011) Intervertebral Disc Repair by Autologous Mesenchymal Bone Marrow Cells: A Pilot Study. Transplantation 92: 822-828.
SANCHEZ, A., SCHIMMANG, T. AND GARCÍA-SANCHO, J. (2012) Cell and tissue therapy in regenerative medicine. Adv Exp Med Biol. 741: 89-102.
ALONSO, M.T., MANJARRES, I.M. & GARCIA-SANCHO, J (2012) Privileged coupling between Ca2+ entry through plasma membrane store-operated Ca2+ channels and the endoplasmic reticulum Ca2+ pump. Mol. Cel. Endocrinol. 353: 37–44
GARCÍA AG, PADÍN F, FERNÁNDEZ-MORALES JC, MAROTO M, GARCÍA-SANCHO J. (2012) Cytosolic organelles shape calcium signals and exo-endocytotic responses of chromaffin cells. Cell Calcium. 51: 309-320
GARCÍA-SANCHO J, DE DIEGO AM, GARCÍA AG. (2012) Mitochondria and chromaffin cell function. Pflugers Arch. 464: 33-41.
LÓPEZ-DOMÉNECH G, SERRAT R, MIRRA S, D'ANIELLO S, SOMORJAI I, ABAD A, VITUREIRA N, GARCÍA-ARUMÍ E, ALONSO MT, RODRIGUEZ-PRADOS M, BURGAYA F, ANDREU AL, GARCÍA-SANCHO J, TRULLAS R, GARCIA-FERNÀNDEZ J, SORIANO E. (2012) The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. Nat Commun. 3:814. doi: 10.1038/ncomms1829. PMID:22569362.
DURÁN ALONSO MB, FEIJOO-REDONDO A, CONDE DE FELIPE M, CARNICERO E, GARCÍA AS, GARCÍA-SANCHO J, RIVOLTA MN, GIRÁLDEZ F, SCHIMMANG T. (2012) Generation of inner ear sensory cells from bone marrow-derived human mesenchymal stem cells. Regen Med. 7: 769-83.
OROZCO L, MUNAR A, SOLER R, ALBERCA M, SOLER F, HUGUET M, SENTÍS J, SÁNCHEZ A, GARCÍA-SANCHO J. (2013) Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Transplantation 95: 1535-1541.
GARCIA-SANCHO J (2014) The coupling of plasma membrane calcium entry to calcium uptake by endoplasmic reticulum and mitochondria. J. Physiol. 592: 261-268.
RODRIGUEZ-GARCÍA A, NAVAS P, ROJO J, AULESTIA FJ, GALLEGO-SANDÍN S, GARCIA-SANCHO J & ALONSO MT (2014) GAP, a new fluorescent aequorin-based biosensor for subcellular Ca2+ dynamics. Proc. Nat. Acad. Sci. USA, 111: 2584-2589.
OROZCO L, MUNAR A, SOLER R, ALBERCA M, SOLER F, HUGUET M, SENTÍS J, SÁNCHEZ A, GARCÍA-SANCHO J. (2014) Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells: Two-Year Follow-up Results. Transplantation 97: e66-e68.
VILLANUEVA J, VINIEGRA S, GIMENEZ-MOLINA Y, GARCÍA-MARTINEZ V, EXPÓSITO-ROMERO G, DEL MAR FRANCES M, GARCÍA-SANCHO J, GUTIÉRREZ LM (2014) The position of mitochondria and ER in relation to that of the secretory sites in chromaffin cells. J Cell Sci. 127: 5105-5114.
VEGA A, DEL CANTO F, ALBERCA M, GARCÍA V, MUNAR A, OROZCO L, SOLER R, FUERTES JJ, HUGUET M, SÁNCHEZ A, AND GARCÍA-SANCHO J (2015) Treatment of knee osteoarthritis with allogeneic mesenchymal stem cells: a randomized controlled trial. Transplantation, 99: 1681-1690.
AULESTIA FJ, ALONSO MT & GARCIA-SANCHO J (2015) Calcium homeostasis in cis- and trans-Golgi network. Biochem. J., 466: 455-465.
SENOVILLA, L, NUÑEZ, L, CAMPOS, JM, DE LUIS, DA, ROMERO, E, GARCÍA-SANCHO, J & VAILLALOBOS, C (2015) Single-cell phenotypic characterization of human pituitary GHomas and non-functioning adenomas based on hormone content and calcium responses to hypothalamic releasing hormones. Front Oncol.5: 124. doi: 10.3389
RAMÍREZ BE, SÁNCHEZ A, HERRERAS JM, FERNÁNDEZ I, GARCÍA-SANCHO J, NIETO-MIGUEL T, & CALONGE M. (2015) Stem Cell Therapy for Corneal Epithelium Regeneration following Good Manufacturing and Clinical Procedures. BioMed. Res. Int., 2015:408495. doi: 10.1155/2015/408495.
RODRIGUEZ-PRADOS M, ROJO-RUIZ J, AULESTIA FJ, GARCÍA-SANCHO J & ALONSO MT (2015) A new low-Ca2+ affinity GAP indicator to monitor high Ca2+ in organelles by luminescence. Cell Calcium, 58: 558-64.
ALONSO MT, NAVAS-NAVARRO P, GARCÍA-SANCHO J. (2017) A Microplate-Based Bioluminescence Assay of Mitochondrial Calcium Uptake. Methods Mol Biol. 1567: 245-253
NAVAS-NAVARRO P, ROJO-RUIZ J, RODRIGUEZ-PRADOS M, GANFORNINA MD, LOOGER LL,ALONSO MT, GARCÍA-SANCHO J. (2016) GFP-Aequorin Protein Sensor for Ex Vivo and In Vivo Imaging of Ca(2+) Dynamics in High-Ca(2+) Organelles. Cell Chem Biol., 23: 1-8.
NORIEGA DC, ARDURA F, HERNÁNDEZ-RAMAJO R, MARTÍN-FERRERO MA, SÁNCHEZ-LITE I, TORIBIO B, ALBERCA M, GARCÍA V, MORALEDA JM, SÁNCHEZ, A & JAVIER GARCÍA-SANCHO, J (2017) Intertebral disc repair by allogeneic mesenchymal bone marrow cells: a randomized controlled trial. Transplantation 101: 1945–1951.
ALONSO MT, RODRÍGUEZ-PRADOS M, NAVAS-NAVARRO P, ROJO-RUIZ J, GARCÍA-SANCHO J. (2017) Using aequorin probes to measure Ca(2+) in intracellular organelles. Cell Calcium 64: 3-11
ALONSO MT, ROJO-RUIZ J, NAVAS-NAVARRO P, RODRÍGUEZ-PRADOS M, GARCÍA-SANCHO J. (2017) Measuring Ca(2+) inside intracellular organelles with luminescent and fluorescentaequorin-based sensors. Biochim Biophys Acta 1864: 894-899
ARDUINO DM, WETTMARSHAUSEN J, VAIS H, NAVAS-NAVARRO P, CHENG Y, LEIMPEK A, MA Z, DELRIO-LORENZO A, GIORDANO A, GARCIA-PEREZ C, MÉDARD G, KUSTER B, GARCÍA-SANCHO JG, MOKRANJAC D, FOSKETT JK, ALONSO MT, PEROCCHI F (2017) Systematic identification of MCU modulators by orthogonal interspecies chemical screening Mol Cell, 67: 711-723
GARCÍA-SANCHO J, SANCHEZ A, VEGA A, NORIEGA DC, NOCITO M. (2017) Influence of HLA Matching on the Efficacy of Allogeneic Mesenchymal Stromal Cell Therapies for Osteoarthritis and Degenerative Disc Disease. Transplantation Direct 3: e205. doi: 10.1097/TXD.0000000000000724.
REDONDO LM, GARCÍA V, PERAL B, VERRIER A, BECERRA J, SÁNCHEZ A, GARCÍA-SANCHO J.(2018) Repair of maxillary cystic bone defects with mesenchymal stem cells seeded on a cross-linked serum scaffold. J Craniomaxillofac Surg 46: 222-229.
BARBADO J, TABERA S, SÁNCHEZ A, GARCÍA-SANCHO J. (2018) Therapeutic potential of allogeneic mesenchymal stromal cells transplantation for lupus nephritis. Lupus 27: 2161-2165
DURAN ALONSO MB, LOPEZ HERNANDEZ I, DE LA FUENTE MA, GARCIA-SANCHO J, GIRALDEZ F, SCHIMMANG T. (2018) Transcription factor induced conversion of human fibroblasts towards the hair cell lineage. PLoS One 13: e0200210.
ROJO-RUIZ J, RODRÍGUEZ-PRADOS M, DELRIO-LORENZO A, ALONSO MT, GARCÍA-SANCHO J. (2018) Caffeine chelates calcium in the lumen of the endoplasmic reticulum. Biochem J 475: 3639-3649. doi: 10.1042/BCJ20180532.
CALONGE M, PÉREZ I, GALINDO S, NIETO-MIGUEL T, LÓPEZ-PANIAGUA M, FERNÁNDEZ I, ALBERCA M, GARCÍA-SANCHO J, SÁNCHEZ A, HERRERAS JM. (2019) A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency. Transl Res 206: 18-40.
CALATAYUD C, CAROLA G, FERNÁNDEZ-CARASA I, VALTORTA M, JIMÉNEZ-DELGADO S, DÍAZ M, SORIANO-FRADERA J, CAPPELLETTI G, GARCÍA-SANCHO J, RAYA Á, CONSIGLIO A. (2019) CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons. Sci Rep. 2019 9: 6811. doi: 10.1038/s41598-019-43080-2. PubMed PMID: 31048719.
DELRIO-LORENZO A, ROJO-RUIZ J, ALONSO MT, GARCIA-SANCHO J (2020) Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila. J Cell Sci. 133: jcs240879
RODRÍGUEZ-PRADOS M, ROJO-RUIZ J, GARCÍA-SANCHO J, ALONSO MT. (2020) Direct monitoring of ER Ca2+ dynamics reveals that Ca2+ entry induces ER-Ca2+ release in astrocytes. Pflugers Arch. 472: 439-448.
