Marcel Méchali - Selected Publications#

H-Index: 60

Méchali M. (2022) Replication timing and genetic instability. Science, 377,1259-1260.

Akerman, I., Kasaai, B., Bazarova, A., Sang, P.B., Peiffer, I., Artufel, M., Derelle, R., Smith, G., Kinet, S., Romano, M., Theillet, C., Taylor, N., Ballester, B., and Méchali, M. (2020) A predictable, conserved DNA sequence signature defines Human Core DNA replication origins. Nat Com., 11, 4826, 1-15; 41 citations.

Prorok P., Artufel, M., Aze, A., Coulombe, P., Peifer I., Lacroix L., Guédin A., Mergny J.L., Damaschke J., Schepers, A., Cayrou, C., Teulade-Fichou, M.P., Ballester, B., and Méchali, M. (2019) Involvement of G-quadruplex regions in mammalian replication origin activity. Nature Com. 10, 3274. 130 citations

Rodríguez-Martínez M, Pinzón N, Ghommidh C, Beyne E, Seitz H, Cayrou C, and Méchali M. (2017) The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans. Nat Struct Mol Biol. 24, 290-299. This article has been the subject of a News and Views.

Traver, S., Coulombe, P., Kitzmann, M., Peiffer, I., Hutchins, J., Latreille, D and Méchali, M. (2015) MCM9 is Required for Mammalian DNA Mismatch Repair. Mol. Cell 59, 831-839.

Cayrou C, Ballester B, Peiffer I, Fenouil R, Coulombe P, Andrau JC, van Helden J, Méchali M. (2015), The chromatin environment shapes DNA replication origin organization and defines origin classes. Genome Res. 25, 1873-1885. 165 citations.

Fragkos, M., Ganier, O., Coulombe, P. and Méchali, M. (2015) DNA replication origin activation in space and time. Nature Rev. Mol. Cell Biol. 16, 360-374. 545 citations

Lutzmann, M., Grey, C., Traver, S., Ganier, O., Maya-Mendoza, A., Ranisavljevic, N., Bernex, F., Nishiyama, A., Montel, N., Gavois, E., Forichon, L., de Massy, B., and Méchali, M. (2012) MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination. Mol Cell. 47, 523-534. This article was the subject of a News and Views article. Recommended as “Must Read” by The Faculty of 1000. 212 citations.

Leonard A.C. and Méchali, M. (2013) DNA Replication Origins. Cold Spring Harbor Perspectives in Biology 5, 10. 284 citations

Ganier, O., Bocquet, S., Peiffer, I., Brochard, V., Arnaud, P., Puy, A., Jouneau, A., Feil, R., Renard, J.P., and Méchali M. (2011) Synergic reprogramming of mammalian cells by combined exposure to mitotic Xenopus egg extracts and transcription factors. Proc Natl Acad Sci U S A., 108, 17331-17336. Article highlighted by a full comment in PNAS.

Cayrou C., Coulombe P, Vigneron A., Stanojcic S., Ganier O., Peiffer I., Rivals E., Puy A., Laurent-Chabalier S., Desprat R., and Méchali M. (2011) Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features. Genome Res., 9, 1438-1449. 393 citations