Eörs Szathmary - Selected publications#

(1) Szathmáry, E. (1985) Origin of microtubules, undulipodia and centrioles: a compromise hypothesis. In: (J. Mlíkovsky & V.J.A Novák, eds.) Evolution and Morphogenesis. pp 373-379. Academia, Praha.

(2) Szathmáry, E. (1986) The eukaryotic cell as an information integrator. Endocytobiol. Cell Res. 3, 113-132.

(3) Szathmáry, E. (1986) Some remarks on hypercycles and the stochastic corrector model. Endocytobiol. Cell Res. 3, 337-339.

(4) Szathmáry, E. (1987) Early evolution of microtubules and undulipodia. BioSystems 20, 115-131.

(5) Szathmáry, E. & Demeter L. (1987) Group selection of early replicators and the origin of life. J. theor Biol. 128, 463-486.

(6) Szathmáry, E., Kotsis, M. & Scheuring I. (1988) Limits of hyperbolic growth and selection in molecular and biological populations. In: (T.G. Hallam, L. Gross & S. Levin eds.): Mathematical Ecology. pp. 46-68. World Scientific, Singapore.

(7) Szathmáry, E. (1988) A hypercyclic illusion. J. theor. Biol. 134, 561-563.

(8) Szathmáry, E. & Gladkih, I. (1989) Sub-exponential growth and coexistence of non-enzymatically replicating templates. J. theor. Biol. 138, 55-58.

(9) Szathmáry, E. (1989) The cost of splicing and the late origin of introns. Trends Ecol. Evol. 4, 109-110.

(10) Szathmáry, E. (1989) The integration of the earliest genetic information. Trends Ecol. Evol. 4, 200-204.

(11) Szathmáry, E. (1989) The emergence, maintenance, and transitions of the earliest evolutionary units. Oxf. Surv. Evol. Biol. 6, 169-205.

(12) Szathmáry, E. (1990) RNA worlds in test tubes and protocells. In: (Maynard Smith, J. & Vida, G. eds): Organizational Constraints on the Dynamics of Evolution. Manchester Univ. Press. pp. 3-14.

(13) Szathmáry, E., Scheuring I., Kotsis, M. & Gladkih, I. (1990) Sexuality of eukaryotic unicells: hyperbolic growth, coexistence of facultative parthenogens, and the repair hypothesis. In: (Maynard Smith, J. & Vida, G. eds): Organizational Constraints on the Dynamics of Evolution. Manchester Univ. Press. pp. 279-286.

(14) Vida, G., Szathmáry, E., Németh, G., Hegedűs, Cs., Molnár, I. & Juhász-Nagy, P. (1990) Towards modelling community evolution: the Phylogenerator. In: (Maynard Smith, J. & Vida, G., eds): Organizational Constraints on the Dynamics of Evolution. Manchester Univ. Press. pp. 409-422.

(15) Szathmáry, E. (1990) Towards the evolution of ribozymes. Nature 344, 115.

(16) Szathmáry, E., Scheuring, I., Hegedűs, Cs., Németh, G. Molnár, I. & Vida, G. (1990) The engagement of the Red Queen and King Midas in the Phylogenerator Model. Coenoses 5, 130-141.

(17) Szathmáry, E. (1991) Codon swapping as a possible evolutionary mechanism. J. Mol. Evol. 32, 178-182.

(18) Szathmáry, E. (1991) Variational principles, behavioural adaptations, and selection hierarchies. Behavior. Brain Sci. 14, 107-108.

(19) Szathmáry, E. (1991) Four letters in the genetic alphabet: a frozen evolutionary optimum? Proc. R. Soc. Lond. B 245, 91-99.

(20) Szathmáry, E. & Kövér, Sz. (1991) A theoretical test of the DNA repair hyothesis for the maintenance of sex in eukaryotes. Genet. Res. 58, 157-165.

(21) Szathmáry, E. (1991) Simple growth laws and selection consequences. Trends Ecol. Evol. 6, 366-370.

(22) Szathmáry, E. (1991) Common interest and novel evolutionary units. Trends Ecol. Evol. 6, 407-408.

(23) Szathmáry, E. (1992) Natural selection and the dynamical coexistence of defective and complementing virus segments. J. theor. Biol. 157, 383-406.

(24) Szathmáry, E. (1992) What determines the size of the genetic alphabet? Proc. Natl. Acad. Sci. USA 89, 2614-2618.

(25) Szathmáry, E. & Zintzaras, E. (1992) A statistical test of hypotheses on the organization and origin of the genetic code. J. Mol. Evol. 35, 185-189.

(26) Szathmáry, E. (1992) Viral sex, levels of selection, and the origin of life. J. theor. Biol. 159, 99-109.

(27) Szathmáry, E. (1993) Co-operation and defection: playing the field in virus dynamics. J. theor. Biol. 165, 341-356.

(28) Szathmáry, E. (1993) Molecular variation and evolution of viruses. Trends Ecol. Evol. 8, 8-9.

(29) Szathmáry, E. (1993) Do deleterious mutations act synergistically? Metabolic control theory provides a partial answer. Genetics 133, 127-132.

(30) Szathmáry, E. (1993) A note on the reduction of the dynamics of multilocus diploid genetic systems with mutliplicative fitness. J. theor. Biol. 164, 351-358.

(31) Maynard Smith, J. & Szathmáry, E. (1993) The origin of chromosomes I. Selection for linkage. J. theor Biol. 164, 437-446.

(32) Szathmáry, E. & Maynard Smith, J. (1993) The origin of chromosomes II. Molecular mechanisms. J. theor Biol. 164, 447-454.

(33) Szathmáry, E. (1993) Coding coenzyme handles: A hypothesis for the origin of the genetic code. Proc. Natl. Acad. Sci. USA 90, 9916-9920.

(34) Szathmáry, E. (1994) Toy models of simple forms of multicellularity, soma and germ. J. theor. Biol. 169, 125-132.

(35) Szathmáry, E. (1994) Self-replication and reproduction: From molecules to protocells. In: (Fleischaker, G. R., Colonna, S. & Luisi, P. L. eds) Self-Production of Supramolecular Structures. From Synthetic Structures to Models of Minimal Living Systems. NATO ASI Series. Kluwer Academic Publishers, Dordrecht, pp. 65-73.

(36) Maynard Smith, J. & Szathmáry, E. (1995) The Major Transitions in Evolution. Freeman & Co., Oxford.

(37) Jablonka, E. & Szathmáry, E. (1995) The evolution of information storage and heredity. Trends Ecol. Evol. 10, 206-211.

(38) Szathmáry, E. & Maynard Smith, J. (1995) The major evolutionary transitions. Nature 374, 227-232.

(39) Szathmáry, E. (1995) A classification of replicators and lambda-calculus models of biological organization. Proc. R. Soc. Lond. B 260, 279-286.

(40) Grey, D., Hutson, V. & Szathmáry, E. (1995) A re-examination of the stochastic corrector model. Proc. R. Soc. Lond. B 262, 29-35.

(41) Maynard Smith, J. & Szathmáry, E. (1995) Language and Life. In: (M. P. Murphy & L. A. J. O'Neill, eds) What is Life? The Next Fifty Years. Speculations on the Future of Biology. pp. 67-77. Cambridge Univ. Press.

(42) Szathmáry, E. (1996) From RNA to language. Curr. Biol. 6, 764.

(43) Szathmáry, E. (1996) Coding coenzyme handles and the origin of the genetic code. In: (A. Müller, A. Dress & F. Vögtle, eds) From Simplicity to Complexity in Chemistry -- and Beyond. Part I. Vieweg, Braunschweig, pp. 33-41.

(44) Maynard Smith, J. & Szathmáry, E. (1996) On the likelihood of habitable worlds. Nature 384, 107.

(45) Fagerström, T., Jagers, P., Schuster, P. & Szathmáry, E. (1996) Biologists put on mathematical glasses. Science 274, 2039-2040.

(46) Szathmáry, E. & Maynard Smith, J. (1997) From replicators to reproducers: The first major transitions leading to life. J. theor. Biol. 187, 555-571.

(47) Varga, Z. & Szathmáry, E. (1997) An extremum principle for parabolic competition. Bull. Math. Biol. 59, 1145-1154.

(48) Szathmáry, E. (1997) Origins of life – The first two billion years. Nature 387, 662-663.

(49) Sigmund, K. & Szathmáry, E. (1998) On merging lines and emerging units. Nature 392, 439-441.

(50) Szathmáry, E. (1999) Chemes, Genes, Memes: A revised classification of replicators. Lectures on Mathematics in the Life Sciences. 26, 1-10.

(51) Szathmáry, E. (1999) The origin of the genetic code: amino acids as cofactors in an RNA world. Trends Genet. 15, 223-229.

(52) Kövér, Sz. és Szathmáry, E. (1999) Hybrid theories of sex. J. Evol. Biol. 12:1032-1033.

(53) Maynard Smith, J. & Szathmáry, E. (1999) The Origins of Life. Oxford Univ. Press.

(54) Szathmáry, E. (2000) Reply: Certain uncertainties about the origin of the genetic code. Trends Genet. 16, 18-19.

(55) Czárán, T. and Szathmáry, E. (2000) Coexistence of replicators in prebiotic evolution. In: Dieckmann, U., Law, R. & Metz, J.A.J. (eds.) The Geometry of Ecological Interactions: Simplifying Spatial Complexity, pp. 116-134, IIASA and Cambridge University Press.

(56) Szathmáry, E. (2000) The evolution of replicators. Phil. Trans. R. Soc. Lond. B. 355, 1669-1676.

(57) Von Kiedrowski, G. & Szathmáry, E. (2000) Selection versus coexistence of parabolic replicators spreading on surfaces. Selection 1, 173-179.

(58) Szathmáry, E. (2000) In Humboldt’s footspets. Trends Ecol. Evol. 15, 178-179.

(59) Szathmáry, E. (2001) Biological information, kin selection, and evolutionary transitions. Theor. Pop. Biol. 59, 11-14.

(60) Szathmáry, E. (2001) Evolution. Developmental circuits rewired. Nature 411, 143-145.

(61) Szathmáry, E., Jordán, F. & Pál, C. (2001) Molecular biology and evolution. Can genes explain biological complexity? Science 292, 1315-1316.

(62) Szathmáry, E. (2001) Origin of the human language faculty: the language amoeba hypothesis. In (J. Trabant & S. Ward, Eds.): New Essays on the Origin of Language. Berlin/New York: Mouton/de Gruyter, pp. 41-51.

(63) Podani, J., Oltvai. N. Z., Jeong, H., Tombor, B. Barabási, A.-L. & Szathmáry, E. (2001) Comparable system-level organization of Archaea and Eukaryotes. Nature Genet. 29, 54-56.

(64) Scheuring, I. & Szathmáry, E. (2001) Survival of replicators with parabolic growth tendency and exponential decay. J. theor. Biol. 212, 99-105.

(65) Szathmáry, E. (2001) Theories of origin of life. In: S. Brenner and J. H. Miller (eds): Encyclopedia of Genetics. Academic Press, London. Pp. 1387-1394.

(66) Meszéna, G. & Szathmáry, E. (2001) The adaptive dynamics of parabolic replicators. Selection 2, 147-159.

(67) Zintzaras, E., Mauro, S. & Szathmáry, E. (2002) „Living” under the challenge of information decay: the stochastic corrector model versus hypercycles. J. theor. Biol. 217, 167-181.

(68) Szathmáry, E. (2002) Units of evolution and units of life. In: Pályi, G., Zucchi, L. & Caglioti, L. (eds) Fundamentals of Life. pp. 181-195. Elsevier, Paris.

(69) Szabó, P., Scheuring, I., Czárán, T. & Szathmáry, E. (2002) In silico simulations reveal that replicators with limited dispersal evolve towards higher efficiency and fidelity. Nature 420, 360-363.

(70) Wolpert, L. & Szathmáry, E. (2002) Multicellularity: evolution and the egg. Nature 420, 745.

(71) Gulyás, B. & Szathmáry, E. (2002) Monkeys – a great asset to reveal human cognitive functions. Neuroreport 13, 2167-2168.

(72) Szathmáry, E. (2002) Cultural processes: the latest major transition in evolution. In: L. Nadel (ed.) Encyclopedia of Cognitive Science Nature Publishing Group, Macmillan, London. DOI: 10.1002/0470018860.s00716

(73) Szathmáry, E. (2003) Concepts and dynamics: a theoretical issue of OLEB. Orig Life Evol. Biosph. 33, 313-317.

(74) Gánti, T., Horváth, A., Gesztesi, A., Bérczi, Sz. & Szathmáry, E. (2003) Dark dune spots: possible biomarkers on Mars? Orig. Life Evol. Biosph. 33, 515-577.

(75) Santos, M,. Zintzaras, E. & Szathmáry, E. (2003) Origin of sex revisited. Orig. Life Evol. Biosph. 33, 405-432.

(76) Szathmáry, E. & Wolpert, L. (2003) The evolution of multicellularity. In: Hammerstein, P. (ed.) Genetic and Social Mechanisms of Cooperation. pp. 271-290. MIT Press, Cambridge, MA.

(77) Szathmáry, E. (2003) Why are there four letters in the genetic alphabet? Nat. Rev. Genet. 4, 995-1001.

(78) Szathmáry, E. (2003) The biological significance of Gánti’s work in 1971 and today. In: T. Gánti: The Principles of Life. Oxford Univ. Press, pp. 157-168.

(79) Santos, M,. Zintzaras, E. & Szathmáry, E. (2004) Recombination in primeval genomes: a step forward but still a long leap from maintaining a sizeable genome. J. Mol. Evol. 59, 507-519.

(80) Szathmáry, E & Hammerstein, P. (2004) Obituary: John Maynard Smith (1920-2004). Nature 429, 258-259.

(81) Szathmáry, E (2004) From biological analysis to synthetic biology. Curr. Biol. 14, R145-146.

(82) Lenton, T.M., Schellnhuber, H. J. & Szathmáry, E. (2004) Climbing the co-evolution ladder. Nature 431, 913.

(83) Szathmáry, E (2004) Knowledge and belief in evolutionary biology. In: W. Löffl er, P. Weingartner (eds), Knowledge and Belief. Wissen und Glauben. Öbv& Hpt, Wien. Pp. 364-374.

(84) Fernando, C., Santos, M. & Szathmáry, E. (2005) Evolutionary potential and requirements for minimal protocells. Top. Curr. Chem. 259, 167-211.

(85) Szathmáry, E (2005) Path dependence and historical contingency in biology. In: A. Wimmer and R. Kössler (eds), Understanding Change. Palgrave Macmillan, Basingstoke, in press.

(86) Szathmáry, E (2005) Life: in search of the simplest cell. Nature 433, 469-470.

(87) Kun, Á., Santos, M. & Szathmáry, E (2005) Real ribozymes suggest a relaxed error threshold. Nat. Genet. 37, 1008-1011.

(88) Kun, Á., Maurel, M.-C. & Santos, M. & Szathmáry, E (2005) Fitness Landscapes, Error Thresholds, and Cofactors in Aptamer Evolution. In: S. Klussmann (ed.) The Aptamer Handbook. Wiley-Vch, Weinheim, pp. 54-92.

(89) Szathmáry, E & Santos, M. (2006) He would have deserved to live forever: John Maynard Smith (1920-2004). J. theor. Biol. 239, 129.

(90) Fontanari, J.F., Santos, M. & Szathmáry, E (2006) Coexistence and error propagation in pre-biotic vesicle models: A group selection approach. J. theor. Biol. 239, 247-256.

(91) Vergne, J., Cognet, J. A., Szathmáry, E & Maurel, M. C. (2006) In vitro selection of halo-thermophilic RNA reveals two families of resistant RNA. Gene 371, 182-193.

(92) Szathmáry, E (2006) The origin of replicators and reproducers. Phil. Trans. R. Soc. Lond. B. Biol. Sci. 361, 1761-1776.

(93) Frégnac, Y., Blatow, M., Changeux, J.-P., DeFelipe, J., Lansner, A., Maas, W., McCormick, D.A., Michel, C.M., Monyer, H., Szathmáry, E. & Yuste, R. (2006) Group report: Neocortical microcircuits—Ups and DOWNs in cortical computation. In: S. Grillner and A.M. Graybiel (eds): Microcircuits. The Interface between Neurons and Global Brain Function. MIT Press, Cambridge, Ma. pp. 393-433.

(94) Számadó, S. & Szathmáry, E. (2006) Competing selective scenarios for the emergence of natural language. Trends Ecol. Evol. 21, 555-561.

(95) Szathmáry, E (2006) Evolution. Darwin for all seasons. Science 313, 306-307.

(96) Szathmáry, E., Szatmáry, Z., Ittzés, P., Gergő, O., Zachár, I., Huszár, F., Fedor, A., Varga, M. & Számadó, S. (2007) In silico evolutionary developmental neurobiology and the origin of natural language. In: (Lyon, C., Nehaniv, C. L. & Cangelosi, A., eds) Emergence of Communication and Language. Springer, London. pp. 151-187.

(97) Szathmáry, E., Gánti, T., Pócs, T., Horváth, A., Kereszturi, Á., Bérczi, S. & Sik, A. (2007) Life in the dark dunes of Mars: a testable hypothesis. In: R. Pudritz, P. Higgs and J. Stone (eds) Planetary Systems and the Origins of Life. Cambridge Univ. Press, pp. 241-262.

(98) Szathmáry, E (2007) Coevolution of metabolic networks and membranes: the scenario of progressive sequestration. Phil. Trans. R. Soc. Lond. B. Biol. Sci. 362, 1781-1787.

(99) Fernando, C., Von Kiedrowski, G. & Szathmáry, E. (2007) A Stochastic Model of Nonenzymatic Nucleic Acid Replication: "Elongators" Sequester Replicators. J Mol Evol. 64, 572-585.

(100) Jakó, É, Ittzés, P, Szenes, Á, Kun, Á, Szathmáry, E. & Pál, G. (2007) In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership. Nucleic Acids Res. 35, 5593-5609.

(101) Szathmáry, E. (2008) The genetic code and natural language: their nature, origins and relation. In: P. Walde, F. Kraus (eds): An den Grenzen des Wissens. Vdf Hochschulverlag AG an der ETH Zürich. Pp. 185-207.

(102) Kun, Á., Pongor, S., Jordán, F. & Szathmáry, E. (2008) Catalytic Propensity of Amino Acids and the Origins of the Genetic Code and Proteins. In. M. Barbieri (ed.) Codes of Life, Springer-Verlag, pp. 39-58.

(103) Szathmáry, E. (2008) Towards an understanding of language origins. In. M. Barbieri (ed.) Codes of Life, Springer-Verlag, pp. 283-313.

(104) Kun, Á., Papp, B. & Szathmáry, E. (2008) Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks. Genome Biol. 9, R51.

(105) Könnyű, B., Czárán, T. & Szathmáry, E. (2008) Prebiotic replicase evolution in a surface-bound metabolic system: parasites as a source of adaptive evolution. BMC Evol. Biol. 8, 267.

(106) Santos, M. & Szathmáry, E. (2008) Genetic hitchhiking can promote the initial spread of strong altruism. BMC Evol. Biol. 8, 281.

(107) Fernando, C. Karishma, K.K. & Szathmáry, E. (2008) Copying of Neuronal Topology by Spike-Time Dependent Plasticity and Error-Correction. PlosONE 3(11), e3775.

(108) Számadó, S. & Szathmáry, E. (2008) Being human: Language: a social history of words. Nature 456, 40-41.

(109) Griesemer, J. & Szathmáry, E. (2009) Gánti’s chemoton model and life criteria. In: S. Rasmussen, M.A. Bedau, L. Chen, D. Deamer, D.C. Krakauer, N.H. Packard & P.F. Stadler (eds): Protocells. Bridging Nonliving and Living Matter. MIT Press, Cambdridge, Ma. pp. 481-512.

Hungarian editions in English and Hungarian

1. Szathmáry, E. (1984) Hyperbolic growth in molecular and biological populations I. Single-species dynamics lacking direct linear growth rates. Abstracta Botanica 8, 137-161.

2. Szathmáry, E. (1985) Hyperbolic growth in molecular and biological populations II. Single-species dynamics with parallel simple and hypercyclic replication. Abstracta Botanica 9, 141-151.

3. Szathmáry, E. (1990) Useful coding before translation: the coding coenzymes handle hypothesis for the origin of the genetic code. In: (B. Lukács et al. eds) Evolution: from Cosmogenesis to Biogenesis. pp. 77-83. KFKI-1990-50/C, Budapest.

4. Szathmáry, E. & Maynard Smith, J. (1993) The origin of genetic systems. Abstracta Botanica 17, 197-206. 5. Szathmáry, E. (1984) Az egyedi szerveződés gyökerei (The roots of individual organization). In: (Vida G., ed.) Evolúció IV. Az evolúcókutatás frontvonalai (Evolution IV. Frontiers of Evolution Research). pp. 37-157, Natura, Budapest.

6. Szathmáry, E. (1986) Dinamikus koegzisztenciális kölcsönhatások prebiológiai rendszerekben I. Áttekintés és perspektívák (Dynamical coexistential interactions in prebiotic systems I. Survey and perspectives). Biológia 34, 3-37.

7. Szathmáry, E. & Demeter, L. (1986) Dinamikus koegzisztenciális kölcsönhatások prebiológiai rendszerekben II. Replikátorok dinamikája kölcsönös, aspecifikus segítség esetén (Dynamical coexistential interactions in prebiotic systems II. Dynamics of replicators with an aspecific, mutual aid). Biológia 34, 39-64.

8. Szathmáry, E. (1986) Kényszerek a korai eukaryota evolúcióban (Constraints in early eukaryotic evolution). Abstracta Botanica 10, 131-144.

9. Szathmáry, E. & Demeter, L. (1989) Az evolúció legkorábbi egységei és az "RNS-világ" (The earliest evolutionary units and the RNA world). Tudomány (Hungarian edn of Sci. Amer.) 5(8), 76-84.

10. Szathmáry, E. (1989) A romlás virágai (Flowers of doom). In: (Koch S., ed.) A tökéletlenség és korlátosság dicsérete (In Praise of Imperfection and Limitedness). pp. 215-274. Gondolat, Budapest.

11. Szathmáry E. (1995) Az algák rendszere. In: (M. Járainé Komlódi, ed.) Pannon Enciklopédia. Magyarország növényvilága. pp. 68-69. Dunakanyar 2000, Budapest.

12. Szathmáry, E. (2000) Szathmáry Eörs. In: Monory M. A. and Tillmann J.A. (eds) Ezredvégi beszélgetések (End-of-Millennium Conversations). Pp. 400-412. Palatinus, Budapest.

13. Szathmáry, E. (2000) Az örökletes információ eredete. Magyar Tudomány 2000/11.

14. Szathmáry, E. (2002) Az emberi nyelvkészség eredete és a „nyelvi amőba”. Magyar Tudomány 2002/1.

15. Szathmáry E. (2003) Miért négybetűs a genetikai ábécé? Magyar Tudomány 48, 2003/5 566-573.

16. Szathmáry, E. (2003) Kulturális folyamatok: Az utolsó nagy evolúciós átmenet. In: Pléh Cs., Kovács Gy. and Gulyás B. (eds): Kognitív idegtudomány. Osiris Kiadó, Budapest, pp. 32-48.

17. Szabó, P., Scheuring, I., Czárán, T. & Szathmáry, E. (2003) Prebiotikus replikáz-evolúció agyagásvány felületeken: molekuláris altruizmus térben explicit rendszerben (A fenti 69. sz. cikk magyar fordítása). Magyar Tudomány 48, 2003/7.835-842.

18. Szathmáry, E. (2003) Az élet keletkezése. Magyar Tudomány 48, 2003/10. 1220-1247.