Göran K. Hansson - SCIENTIFIC PUBLICATIONS#

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1. Bondjers G, Brattsand R, Hansson GK, Björkerud S: Cholesterol transfer and content in regions with defined endothelial integrity from rabbits with moderate hypercholesterolemia. Nutr Metab 20:452-460, 1976.

2. Bondjers G, Hansson GK, Werkö L: Immunpatologiska mekanismer vid ateroskleros. Läkartidn. 73:2815-2817, 1976.

3. Bondjers G, Hansson GK, Brattsand R, Björkerud S: The effect of moderate hypercholesterolemia on the blood-artery cholesterol transfer barrier. Adv Exp Med Biol 82:237-239, 1977.

4. Bylock A, Björkerud S, Brattsand R, Hansson GK, Hansson H-A, Bondjers G: Endothelial structure in rabbits with moderate hypercholesterolemia - a scanning electron microscopic study. Acta path microbiol Scand 85A:671-682, 1977.

5. Bondjers G, Brattsand R, Bylock A, Hansson GK, Björkerud S: Endothelial integrity and atherogenesis in rabbiits with moderate hypercholesterolemia. Artery 3:395-408, 1977.

6. Bondjers G, Björkerud S, Brattsand R, Bylock A, Hansson GK: Endothelial injury in normocholesterolemic and hypercholesterolemic rabbits. In: International Conference on Atherosclerosis; L A Carlson et al, eds. Raven Press, New York 1978, pp 567-577.

7. Hansson GK, Bondjers G, Nilsson L-Å: Plasma protein accumulation in injured endothelial cells. Immunofluorescent localization of IgG and fibrinogen in the rabbit aortic endothelium. Exp Mol Pathol 30:12-26, 1979.

8. Hansson GK, Bylock A, Bondjers G: Endothelial injury and atherosclerosis in relation to the immune and inflammatory systems. In: Immunity and Atherosclerosis. F Pratesi, ed. Academic Press, New York 1980, pp. 69-77.

9. Hansson GK, Bondjers G, Bylock A, Hjalmarsson L: Ultrastructural studies of the localization of IgG in the aortic endothelium and subendothelial intima of atherosclerotic and non-atherosclerotic rabbits. Exp Mol Pathol 33:302-315, 1980.

10. Hansson GK, Bondjers G: Endothelial proliferation and atherogenesis in rabbits with moderate hypercholesterolemia. Artery 7:316-329, 1980.

11. Hansson GK: Endothelial injury and monocyte adhesion in atherogenesis. Experimental studies in the rabbit. Thesis, Gothenburg University. Gotab, Gothenburg 1980.

12. Hansson GK, Björnheden T, Bylock A, Bondjers G: Fc-receptor mediated binding of monocytes to areas with endothelial injury in the rabbit aorta. Exp Mol Pathol 34:264-280, 1981.

13. Björkerud S, Bondjers G, Bylock A, Hansson GK: Studies of arterial endothelial integrity with the dye exclusion test - a review. In: Structure and Function of the Circulation, CJ Schwartz et al., eds. Vol. 3, pp 211-238, Plenum Press, New York 1981.

14. Björntorp P, Hansson GK, Jonasson L, Pettersson P,Sypniewska G: Isolation and characterization of endothelial cells from the epididymal fat pad of the rat. J Lipid Res 24:105-112, 1983.

15. Björnheden T, Bondjers G, Bylock A, Hansson GK: A long-term perfusion system for in vitro studies of rabbit aorta. Arteriosclerosis 3:366-382, 1983.

16. Hansson GK, Schwartz SM: Endothelial dysfunction without cell loss. In: Biochemical Interactions at the Endothelium. A Cryer, ed. Elsevier, Amsterdam 1983, pp 343-361.

17. Hansson GK, Schwartz SM: Evidence for cell death in the vascular endothelium in vivo and in vitro. Am J Pathol 112:278- 286, 1983.

18. Kjellström T, Ahlman H, Dahlström A, Hansson GK, Risberg B: The uptake of 5-hydroxytryptamine in endothelial cells cultured from the pulmonary artery in rats - a cytochemical study. Acta Physiol Scand 120:243-250, 1984.

19. Hansson GK, Starkebaum GA, Benditt EP, Schwartz SM: Fc- mediated binding of IgG to cytoskeletal intermediate filaments in vascular endothelial cells. Proc Natl Acad Sci USA 81:3103-3107, 1984.

20. Hansson GK, Holm J, Kral JG: Accumulation of IgG and complement factor C3 in human arterial endothelium. Acta path microbiol Scand 92A:429-435, 1984.

21. Jonasson L, Hansson GK, Bondjers G, Bengtsson G, Olivecrona T: Immunohistochemical localization of lipoprotein lipase in human adipose tissue. Atherosclerosis 51:313-326, 1984.

22. Jonasson L, Holm J, Skalli O, Gabbiani G, Hansson GK: Expression of class II transplantation antigens on vascular smooth muscle cells in human atherosclerosis. J Clin Invest 76:125-131, 1985.

23. Rozell B, Stenman G, Hansson H-A, Dahl D, Hansson GK, Mark J: Intermediate filaments asnd microfilaments in cultured human pleomorphic adenomas. An immunohistochemical study. Acta path microbiol immunol Scand 93A:335-343, 1985.

24. Hansson GK, Chao S, Schwartz SM, Reidy MA: Aortic endothelial cell death and replication in normal and lipopolysaccharide-treated rats. Am J Pathol 121:123-127, 1985.

25. Hansson GK: The binding of immunoglobulins to cytoskeletal intermediate filaments (letter to the editor). J Immunol Methods 82:185, 1985.

26. Hansson GK: Solid-phase preparation of vimentin-type intermediate filaments for immunoassays. J Immmunol Methods 85:401-407, 1985.

27. Jonasson L, Holm J, Skalli O, Bondjers G, Hansson GK: Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis 6:131-138, 1986.

28. Hansson GK, Jonasson L, Holm J, Claesson-Welsh L: Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant γ chain. Clin Exp Immunol 64:261-268, 1986.

29. Risberg B, Eriksson E, Björk S, Hansson GK: Immunohistochemical localization of plasminogen activators in human saphenous veins. Thromb Res 37:301-308, 1986.

30. Hansson GK, Bondjers G: Endothelial dysfunction and injury in atherosclerosis. Acta Med Scand Suppl 715:11-17, 1987.

31. Hansson GK, Holm J, Jonasson L: Interactions between leukocytes, endothelial cells and smooth muscle cells in atherogenesis. In: Fourth Münster International Arteriosclerosis Symposium: Recent Advances in Arteriosclerosis Research. WH Hauss, RW Wissler, J Grünwald, eds. Rheinisch-Westfälische Akademie der Wissenschaften, vol. 76 pp. 157-164, 1987.

32. Hansson GK, Lagerstedt E, Bengtsson A, Heideman M: IgG binding to cytoskeletal intermediate filaments activates the complement cascade. Exp Cell Res 170:338-350, 1987.

33. Jonasson L, Bondjers G, Hansson GK: Lipoprotein lipase in atherosclerosis: its presence in smooth muscle cells and absence from macrophages. J Lipid Res 28:437-445, 1987.

34. Hansson GK: Pathogenetic mechanisms of arteritis in Kawasaki disease - a critical analysis. Progr Clin Biol Res 250:383-394, 1987.

35. Bengtsson A, Heideman M, Hansson GK: In vivo determination of modulated migration of radiolabeled leukocytes. Arch Surg 122:909-912, 1987.

36. Jonasson L, Holm J, Hansson GK: Smooth muscle cells express Ia antigens during arterial response to injury. Lab Invest 58:310-315, 1988.

37. Jonasson L, Holm J, Hansson GK: Cyclosporin A inhibits smooth muscle proliferation in the vascular response to injury. Proc Natl Acad Sci USA 85:2303-2306, 1988.

38. Rubin K, Tingström A, Hansson GK, Larsson E, Rönnstrand L, Terracio L, Heldin C-H, Fellström B, Klareskog L: Induction of PDGF receptors may regulate cell proliferation in vascular diseases. Lancet 1988 (i):1353-1356.

39. Andersson R, Hansson GK, Söderström T, Jonsson R, Bengtsson B-Å, Nordborg E. HLA-DR expression in the vascular lesion and circulating T lymphocytes of patients with giant cell arteritis. Clin Exp Immunol 73:82-87, 1988.

40. Hansson GK, Jonasson L, Lojsthed B, Stemme S, Kocher O, Gabbiani G: Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. Atherosclerosis 72:135-141, 1988.

41. Fager G, Hansson GK, Ottosson P, Dahllöf B, Bondjers G: Human arterial smooth muscle cells in culture. Effects of platelet-derived growth factor and heparin on growth in vitro. Exp Cell Res 176:319-335, 1988.

42. Hansson GK, Jonasson L, Holm J, Clowes MM, Clowes AW: γ-interferon regulates vascular smooth muscle proliferation and Ia expression in vivo and in vitro. Circ Res, 63:712-719, 1988.

43. Hansson GK, Holm J, Jonasson L, Stemme S: The immune system modulates cellular growth and differentiation in the vessel wall. In: Atherosclerosis VIII, Proc 8th Intl Symp Atherosclerosis, Rome 1988, G Crepaldi, AM Gotto, E Manzato, G Baggio, eds. Pp. 571-574. Excerpta Medica, Amsterdam 1989.

44. Fager G, Hansson GK, Gown AM, Larson DM, Skalli O, Bondjers G: Human arterial smooth muscle cells in culture: Inverse relationships between proliferation and expression of contractile proteins. In Vitro Cell Dev Biol 25:511-520, 1989.

45. Seifert PS, Hugo F, Hansson GK, Bhakdi S. Prelesional complement activation in experimental atherosclerosis. Lab Invest 60:747-754, 1989.

46. Seifert PS, Hansson GK. Decay-accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions. J Clin Invest 84:597-604, 1989.

47. Hansson GK, Holm J, Jonasson L. Detection of activated T lymphocytes in the human atherosclerotic plaque. Am J Pathol 135:169-175, 1989.

48. Hansson GK, Jonasson L, Seifert PS, Stemme S. Immune mechanisms in atherosclerosis (Invited review). Arteriosclerosis 9:567-578, 1989.

49. Stemme S, Jonasson L, Holm J, Hansson GK. Immunologic control of vascular cell growth in arterial response to injury and atherosclerosis. Transpl. Proc. 21:3697-3699, 1989.

50. Hansson GK, Hellstrand M, Rymo L, Rubbia L, Gabbiani G. Interferon-γ inhibits both proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells. J Exp Med 170:1595-1608, 1989.

51. Seifert PS, Hansson GK. Complement receptors and regulatory proteins in human atherosclerotic lesions. Arteriosclerosis 9:802-811, 1989.

52. Hansson GK, Holm J, Jonasson L, Seifert PS, Stemme S. Immunologic control of vascular cell growth and differentiation. J Cardiovasc Pharmacol 14 (suppl 6):S82-S84, 1989.

53. Stemme S, Fager G, Hansson GK: MHC class II antigen expression in human vascular smooth muscle cells is induced by γ-interferon and modulated by tumor necrosis factor and lymphotoxin. Immunology 69:243-249, 1990.

54. Holm J, Hansson GK. Cellular and immunologic features of carotid artery disease in man and experimental animals. Eur J Vasc Surg 4:49-55, 1990.

55. Jonasson L, Hansson GK, Bondjers G, Noe L, Etienne J. Interferon-γ inhibits lipoprotein lipase in human monocyte-derived macrophages. Biochim Biophys Acta 1053:43-48, 1990.

56. Andersson K, Blomstrand C, Frizell M, Hansson GK, Rönnbäck L, Wall M. Likvorcytologi - en värdefull diagnostisk metod vid olika neurologiska frågeställningar. Läkartidn. 87:1761-1764, 1990.

57. Hansson GK, Stemme S, Seifert PS, Holm J. Immune-vascular interactions: Pathogenetic mechanisms that may lead to new therapeutic approaches. In: Applied Cardiovascular Biology 1989; P Zilla, R Fasol, A Callow, eds. Karger, Basel 1990.

58. Hansson GK, Seifert PS, Högh-Kristiansen I, Westin J. Paroxysmal nokturnal hemoglobinuri - en molekyldefekt på cellytan. Läkartidn. 87:3179-3182, 1990.

59. Hansson GK, Stemme S. Lymphokines may regulate cellular growth and differentiation in the atherosclerotic plaque. In: Growth Factors in Health and Disease. B Westermark, C Betsholtz and B Hökfeldt, eds. Nordisk Insulin Symposium No. 4, pp. 109-116. Elsevier, Amsterdam, 1990.

60. Hansson GK. Aspetti immuni e infiammatori dell'aterosclerosi. G Ital Cardiol 20:1059-1061, 1990.

61. Bondjers G, Hansson GK, Olsson G, Pettersson K. Smoking, catecholamines, and their effects on endothelial integrity. Adv Exp Med Biol 273:51-59, 1991.

62. Libby P, Hansson GK. Involvement of the immune system in human atherogenesis: Current knowledge and unanswered questions. Lab Invest 64:5-15, 1991. 63. Thyberg J, Hansson GK. Cyclosporine A inhibits induction of DNA synthesis by PDGF and other peptide mitogens in cultured rat aortic smooth muscle cells and dermal fibroblasts. Growth Factors 4:209-219, 1991.

64. Hansson GK, Seifert PS, Olsson G, Bondjers G. Early infiltration of monocytes and T lymphocytes in atherosclerotic lesions of cholesterol-fed rabbits. Arterioscl Thromb 11:745-750, 1991.

65. Hansson GK, Holm J. Interferon-γ inhibits arterial stenosis after injury. Circulation 84:1266-1272, 1991.

66. Hedin U, Holm J, Hansson GK. Induction of tenascin in rat arterial injury: relationship to altered smooth muscle cell phenotype. Am J Pathol 139:649-656, 1991.

67. Bäck H, Nilsson G, Hansson GK, Rödjer S, Tarkowski A. M-component with reactivity against actin associated with thrombocytopenic purpura. Am J Med 91:429-433, 1991.

68. Hansson GK, Holm J, Holm S, Hedrich H, Fotev Z, Fingerle J. T lymphocytes inhibit the vascular response to injury. Proc Natl Acad Sci USA 88:10530-10534, 1991.

69. Strawn WB, Bondjers G, Kaplan JR, Manuck SB, Schwenke D, Hansson GK, Clarkson TB. Endothelial dysfunction in response to psychosocial stress in monkeys. Circ Res 68:1270-1279, 1991.

70. Bondjers G, Glukhova M, Hansson GK, Postnov YV, Reidy MA, Schwartz SM. Hypertension and atherosclerosis - cause and effect, or two effects with one unknown cause? Circulation 84 (suppl VI):VI-2 - VI-16, 1991.

71. Hansson GK, Stemme S. The role of T lymphocyte activation in arteriosclerosis and vascular inflammation. Abh. Rheinisch-Westfälische Akad. der Wissenschaften, 76:31-35, 1991.

72. Stemme S, Rymo L, Hansson GK. Polyclonal origin of T lymphocytes in human atherosclerotic plaques. Lab Invest 65:654-660, 1991.

73. Hansson GK. Immune mechanisms in plaque formation. Atherosclerosis Reviews 23:169-176, 1991.

74. Hansson GK, Andersson M, Jarl H, Stemme S. Flow cytometric analysis of reticulocytes using an RNA-binding fluorochrome. Scand J Clin Lab Invest 52:35-41, 1992.

75. Geng Y-j, Hansson GK. Interferon-γ inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J Clin Invest 89:1322-1330, 1992.

76. Stemme S, Holm J, Hansson GK: T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45R0 and the integrin VLA-1. Arterioscl Thromb 12:206-211, 1992.

77. Hansson GK, Stemme S, Geng Y-j, Holm J: Can immunocompetent cells and their cytokines play a role in atherogenesis? Nouv Rev Fr Hematol 34:S43-S46, 1992.

78. Stemme S, Patarroyo M, Hansson GK: Adhesion of activated T lymphocytes to vascular smooth muscle cells and dermal fibroblasts is mediated by β1- and β2-integrin receptors. Scand J Immunol 36:233-242, 1992.

79. Geng Y-j, Hansson GK, Holme E. Interferon-γ and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res 71:1268-1276, 1992.

80. Hansson GK. Role of immune responses in atherogenesis. Editorial. Nutr Metab Cardiovasc Dis 2:49-51, 1992.

81. Hansson GK. Immune and inflammatory mechanisms in the development of atherosclerosis. Br Heart J 69:S38-S41, 1992.

82. Tarkowski A, Trollmo C, Seifert PS, Hansson GK. Expression of decay-accelerating factor on synovial cells in inflammatory and degenerative arthritides. Rheumatol Int 12:201-205, 1992.

83. Hansson GK: Immunological markers of atherosclerosis. Editorial commentary, The Lancet 341:278, 1993.

84. Schaufelberger C, Stemme S, Andersson R, Hansson GK. T lymphocytes in giant cell arteritic lesions are polyclonal cells expressing α/β type antigen receptors and integrin receptors. Clin.Exp.Immunol. 91:421-428, 1993.

85. Hansson GK: Lymphocyte adhesion and cellular immune reactions in chronic rejection and graft arteriosclerosis. Transpl Proc 25:2050-2051, 1993.

86. Svenningsson A, Hansson GK, Andersen O, Andersson R, Patarroyo M, Stemme S. Adhesion molecule expression on cerebrospinal fluid T lymphocytes. Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls. Ann Neurol 34:155-161, 1993.

87. Johansson SR, Emanuelsson H, Holm J, Hansson GK: Restenos efter angioplastik - klinik och cellbiologi. Läkartidn 90:3310-3317, 1993.

88. Geng YJ, Kodama T, Hansson GK: Differential expression of scavenger receptor isoforms during monocyte-macrophage differentiation. Arterioscler. Thromb. 14:798-806, 1994.

89. Stemme S, Hansson GK: Immune mechanisms in atherosclerosis. Coronary Artery Disease 5:216-222, 1994.

90. Guss SB, Hansson GK: Coronary artery restenosis: Rationale for a trial of gamma-interferon. Primary Cardiology 20:35-38, 1994.

91. Stemme S, Hansson GK: Immune mechanisms in atherogenesis. Ann Med 26:141-146, 1994.

92. Hansson GK: Immunological control mechanisms in plaque formation. In: Arteriosclerosis - New Insights into Pathogenetic Mechanisms and Prevention; Just H, Hort W, Zeiher AM, eds. Basic Research in Cardiology, vol. 89 suppl. 1, 1994, pp. 41-46.

93. Hansson GK: Immunological factors in atherosclerosis. In: Vascular Medicine, Proc. 16th World Congress of the Intl. Union of Angiology, H. Boccalon, ed., pp. 131-136. Excerpta Medica, Amsterdam 1993.

94. Hansson GK, Geng YJ, Holm J, Stemme S: Immune mechanisms in the pathogenesis of atherosclerosis. In: Atherosclerosis, Inflammation, and Thrombosis, GG Neri Serneri, GF Gensini, R Abbate, D Prisco, eds. Pp 163-168. Scientific Press, Florence 1994.

95. Bremell T, Lange S, Holmdahl R, Rydén C, Hansson GK, Tarkowski A: Immunopathological features of rat Staphylococcus aureus arthritis. Infect. Immun. 62:2334-2344, 1994.

96. Geng YJ, Almqvist M, Hansson GK: Full-length cDNA sequence of inducible nitric oxide synthase from rat aortic smooth muscle cells. Biochim. Biophys. Acta 1218:421-424, 1994.

97. Hansson GK, Geng YJ, Holm J, Hårdhammar P, Wennmalm Å, Jennische E: Vascular smooth muscle cells express the inducible isoform of nitric oxide synthase during the response to endothelial injury. J.Exp.Med. 180:733-738, 1994.

98. Geng YJ, Wu Q, Hansson GK: Protein kinase C activation inhibits cytokine-induced nitric oxide synthase in vascular smooth muscle cells. Biochim. Biophys. Acta 1223:125-132, 1994.

99. Grunewald J, Andersson R, Rydberg L, Gigliotti D, Schaufelberger C, Hansson GK, Wigzell H: CD4+ and CD8+ T cell expansions using selected TCR V and J gene segments at the onset of giant cell arteritis. Arthritis Rheum 37:1221-1227, 1994.

100. Geng YJ, Petersson A-S, Wennmalm Å, Hansson GK: Cytokine-induced transcriptional activation of nitric oxide synthase results in nitrosylation of heme- and non-heme iron-nitrosyl complexes in vascular smooth muscle cells. Exp Cell Res 214:418-428, 1994.

101. Hansson GK: Immune and inflammatory mechanisms in the pathogenesis of atherosclerosis. J. Atheroscler. Thromb. 1 suppl 1:86-89, 1994. .

102. Hansson GK: Cytokines regulate proliferation and cytoskeletal organization of vascular smooth muscle cells. Path. Res. Pract. 190:891-894, 1994.

103. Stemme S, Faber B, Holm J, Wiklund O, Witztum JL, Hansson GK: T lymphocytes from human atherosclerotic plaques recognize oxidized LDL. Proc. Natl Acad. Sci USA 92:3893-3997, 1995.

104. Geng, Y-j, Hansson GK. High endothelial cells of postcapillary venules express the scavenger receptor in human peripheral lymph nodes. Scand J Immunol 42:289-296, 1995.

105. Yan Z-q, Hansson GK, Skoogh B-E, Lötvall JO. Induction of nitric oxide synthase in a model of allergic occupational asthma. Allergy 50:760-764, 1995.

106. Geng Y-j, Hansson GK. Cytokine-induced expression of nitric oxide synthase in vascular smooth muscle cells is inhibited by phorbol esters. Nitric oxide, Proc 3rd Intl Symp, 1995. . 107. Geng YJ, Holm J, Nygren S, Bruzelius M, Stemme S, Hansson GK: Expression of macrophage scavenger receptor in atherosclerosis. Relationship to immune activation and the T cell cytokine- interferon-γ. Arteriosclerosis, Thrombosis, and Vascular Biology 15:1995-1202, 1995.

108. Hansson GK, Libby P: The role of the lymphocyte. In: "Atherosclerosis and Coronary Heart Disease", eds. V Fuster, R Ross and E Topol. Pp. 557-568. Raven Press, New York, 1995.

109. Dufva M, Svenningsson A, Hansson GK. Differential regulation of macrophage scavenger receptor isoforms: mRNA quantification using the polymerase chain reaction. J Lipid Res. 36:2282-2290, 1995.

110. Svenningsson A, Andersen O, Hansson GK, Stemme S: Reduced frequency of memory CD8+ T lymphocytes in cerebrospinal fluid and blood of patients with multiple sclerosis. Autoimmunity 21:231-239, 1995.

111. Geng Y.J., Wu Q, Muszynski M, Hansson GK, Libby P: Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-γ, tumor necrosis factor-α and interleukin-1β. Arterioscl Thromb Vasc Biol 16:19-27, 1996.

112. Geng, YJ, Hellstrand, K, Wennmalm, Å, Hansson GK. Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to interferon-γ and tumor necrosis factor-α. Cancer Res 56:866-874, 1996.

113. Hansson GK: Immune responses in atherosclerosis. In: Immune Functions of the Vessel Wall, G K Hansson and P Libby, editors, Pp. 143-158. Harwood Academic Publishers, Amsterdam 1996.

114. Hansson GK, Libby P (Editors): Immune Functions of the Vessel Wall. Harwood Academic Publishers, Amsterdam 1996.

115. Hansson GK: Immune-Vascular interactions in atherosclerosis and transplant arteriosclerosis. In: Transplant Vascular Sclerosis, CG Orosz, editor. Ch. 7, pp. 71-82. R G Landes/Springer, Austin, 1996.

116. Yan Z-q, Yokota T, Zhang W, Hansson GK: Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res 79:38-44, 1996.

117. Zhou, X., Stemme, S., Hansson, GK: Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apo E-deficient mice. Am J Pathol 149:359-366, 1996.

118. Akyürek ML, Fellström BC, Yan, Z-q, Hansson GK, Funa, K, Larsson E: Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic grafts. Am J Pathol 149:1981-1990, 1996.

119. Libby P, Hansson GK, Pober, JS: Atherogenesis and inflammation. In: Molecular Basis of Heart Disease, S Chien, J Breslow, J Leiden, R Rosenberg, C Seidman, editors. Ch 16, pp 349-366. W B Saunders, Philadelphia, 1998.

120. Akyürek ML, Hansson GK, Larsson E, Fellström BC: Nitric oxide generation by nitric oxide synthase isoforms in transplanted vessels. Transplant Proc 29:2571-2572, 1997.

121. Hansson GK, Stemme V, Yokota T: Cytokines and the cardiovascular system. In: Cytokines in Health and Disease, 2nd ed., pp 507-518. Eds. DG Remick and JS Friedland; Marcel Dekker, Inc., New York 1997.

122. Hansson GK: Cell-mediated immunity in atherosclerosis. Current Opinion Lipidol 8:301-311, 1997.

123. Yan Z-q, Hansson GK: Overexpression of inducible NO synthase by neointimal smooth muscle cells. Circ Res 82:21-29, 1998.

124. Yokota T, Ehlin-Henriksson B, Hansson GK: Scavenger receptors mediate adhesion of activated B lymphocytes. Exp Cell Res 239:16-22, 1998.

125. Zhou X, Paulsson G, Stemme S, Hansson GK: Hypercholesterolemia is associated with a Th1/Th2 switch of the autoimmune response in atherosclerotic ApoE-knockout mice. J Clin Invest 101:1717-1725, 1998.

126. Hunter GC, Henderson AM, Westerband A, Kobayashi H, Suzuki, F., Yan Z-q, Sirsjö A, Putnam CW, Hansson GK: The contribution of inducible nitric oxide synthase and cytomegalovirus to the stability of complex carotid plaque. J Vasc Surg 30:36-49, 1999.

127. Sirsjö A, Hansson GK: Proinflammatory cytokines and the regulation of connective tissue. In: Connective Tissue Biology. Integration and Reductionism, eds R Reed and K Rubin. Wenner-Gren International Series. Pp171-178.Portland Press, London 1997.

128. Caligiuri G, Hansson GK: Più del grasso, potè l'antigene. Ricerca Roche 7:48-50, 1997.

129. Hulthe J, Wikstrand J, Lidell A, Wendelhag I, Hansson GK, Wiklund O: Antibody titers against oxidized LDL are not elevated in patients with familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 18:1203-1211, 1998.

130. Wang Q-D, Pernow J, Mu M-Q, Hansson GK, Sirsjö A: Cytokines inhibit release of endothelin and endothelin attenuates inducible nitric oxide production by vascular smooth muscle cells. Submitted for publ., 1998.

131. Yan Z-q, Sirsjö A, Bochaton-Piallat M-L, Gabbiani G, Hansson GK: Augmented expression of inducible nitric oxide synthase in vascular smooth muscle cells during aging depends on enhanced NF-κB activation. Arterioscler Thromb Vasc Biol. 19:2854-2862, 1999.

132. Hansson GK: Atherosclerosis: cell biology and lipoproteins. Curr Opin Lipidology 9:73-75, 1998.

133. Nicoletti A, Kaveri S, Caligiuri G, Bariéty J, Hansson GK: Immunoglobulin treatment reduces atherosclerosis in apoE knockout mice. J Clin Invest 102: 910-918, 1998.

134. Hammar N, Linnersjö A, Hansson GK, Björkander J, Hammarström L: Ischaemic heart disease in primary immunodeficiency. Lancet 352:1786, 1998.

135. Yan, Z-q, Hansson GK: Cytokines in Cardiovascular Diseases. In: Comprehensive Vascular Biology and Pathology - An Encyclopedic Reference. Ed. A. Bikfalvi. Springer Verlag, Berlin & Heidelberg, 1999

136. Nicoletti A, Caligiuri G, Thörnberg I, Kodama T, Stemme S, Hansson GK: The macrophage scavenger receptor type A directs modified proteins to antigen presentation. Eur J Immunol 29:512-521, 1999.

137. Frostegård J, Ulfgren A-K, Nyberg P, Hedin U, Swedenborg J, Andersson U, Hansson GK: Cytokine expression in advanced human atherosclerotic plaques: Dominance of proinflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 145:33-43, 1999.

138. Erl W, Hansson GK, de Martin R, Draude G, Weber KSC, Weber C: Nuclear factor-κB regulates induction of apoptosis and Inhibitor of apoptosis protein-1 in vascular smooth muscle cells. Circ Res 84:668-677, 1999.

139. Caligiuri G, Nicoletti A, Törnberg I, Zhou X, Hansson GK: Effects of sex and age on atherosclerosis and immunity in apoE-deficient mice. Atherosclerosis 145:301-308, 1999.

140. Neuville P, Yan Z-q, Gidlöf A, Pepper MS, Hansson GK, Gabbiani G, Sirsjö A: Retinoic acid regulates arterial smooth muscle cell proliferation and phenotypic features in vivo and in vitro through a RARα-dependent signalling pathway. Arterioscl Thromb Vasc Biol 19:1430-1436. 1999.

141. Caligiuri G, Pernow J, Lévy B, Thorén P, Hansson GK: Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci USA 96:6920-6924, 1999.

142. Forséni M, Hansson GK, Bagger-Sjöbäck D, Hultcrantz M: Infiltration of immunocompetent cells in the middle ear during acute otitis media. Am J Otology 20:152-157, 1999.

143. Hansson GK: T cells, specific immunity and atherosclerosis. Immunol News 6:33-35, 1999.

144. Valen G, Erl W, Eriksson P, Wuttge D, Paulsson G, Hansson GK: Hydrogen peroxide induces mRNA for tumor necrosis factor-α by human endothelial cells. Free Radic Res 31:503-512, 1999.

145 Zhou X, Hansson GK: Detection of B cells and proinflammatory cytokines in atherosclerotic plaques of hypercholesterolemic apoE knockout mice. Scand J Immunol 50:25-30, 1999.

146 Paulsson G, Zhou X, Törnquist E, Hansson GK: Oligoclonal T cell expansions in atherosclerotic lesions of apoE-deficient mice. Arterioscl Thromb Vasc Biol 20:10-17, 2000.

147. Forséni M, Hansson GK, Bagger-Sjöbäck D, Hultcrantz, M: An immunohistochemical study of inducible nitric oxide synthase in the rat middle ear, with reference to tympanosclerosis. Acta Otolaryngol 119:577-582, 1999.

148. Jiang J, Thorén P, Caligiuri G, Hansson GK, Pernow J: Enhanced phenylephrine-induced phasic activity in the atherosclerotic mouse aorta via increased opening of KCa channels: Relation to KV channels and nitric oxide. Brit J Pharmacol, 128:637-646, 1999.

149. Stemme V, Swedenborg J, Claesson H-E, Hansson GK: Expression of cyclooxygenase-2 in human atherosclerotic arteries. Eur J Vasc Surg 20:146-152, 2000.

150. Nicoletti A, Paulsson G, Caligiuri G, Hansson GK: Induction of neonatal tolerance to oxidized LDL reduces atherosclerosis susceptibility in apoE knockout mice. Mol Med 6:283-290, 2000

151. Valen G, Paulsson G, Bennet AM, Hansson GK, Vaage J: Gene expression of inflammatory mediators in different chambers of the human heart. Ann Thorac Surg 70:562-567, 2000.

152. Erl W, Weber C, Hansson GK: Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu2+ and Zn2+. Am J Physiol 278:C1116-C1125, 2000.

153. Valen G, Hansson GK, Dumitrescu A, Vaage J: Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NF-κB and AP-1. Cardiovasc Res 47:49-56, 2000.

154. Svenningsson A, Petersson A-S, Andersen O, Hansson GK: Nitric oxide metabolites in CSF of patients with MS is related to clinical disease course. Neurology 53:1880-1882, 1999.

155. Hansson GK: Inflammation and Immune Response in Atherosclerosis. Current Atherosclerosis Reports. 1:150-155, 1999

156. Hansson GK, Zhou X, Törnquist E, Paulsson G: The role of adaptive immunity in atherosclerosis. Ann. N.Y. Acad. Sci. 902: 53-64, 2000.

157. Hansson GK, Zhou X, Törnquist E, Paulsson G, Caligiuri G: Immune mechanisms in atherosclerosis. In: XXI Congress Eur Soc Cardiol, F Navarro-López, ed. Pp. 215-221. Monduzzi, Bologna 1999.

158. Caligiuri G, Rottenberg M, Nicoletti A, Wigzell H, Hansson GK: Chlamydia pneumoniae infection does not induce atherosclerosis and has a minor effect on cholesterol-induced atherosclerosis in mice. Circulation. 103:2834-2838, 2001.

159. Zhou X, Caligiuri G, Hamsten A, Lefvert AK, Hansson GK: LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscl Thromb Vasc Biol 21: 108-114, 2001.

160. Caligiuri G, Paulsson G, Nicoletti A, Maseri A, Hansson GK: Evidence for antigen-driven T-cell response in unstable angina. Circulation 102:1114-1119, 2000.

161. Nicoletti A, Caligiuri G, Hansson GK: Immunomodulation of atherosclerosis: myth and reality. J Intern Med 247:397-405, 2000.

162. Laurat E, Poirier BV, Tupin E, Caligiuri G, Hansson GK, Bariéty J, Nicoletti A: In vivo downregulation of Th1 immune responses reduces atherogenesis in apoE knockout mice. Circulation. 104:197-202, 2001.

163. Sirsjö A, Gidlöf AC, Olsson A, Törmä H, Ares M, Kleinert H, Förstermann U, Hansson GK: Retinoic acid inhibits nitric oxide synthase-2 expression through retinoic acid receptor-α. Biochem Biophys Res Commun 270:846-851, 2000.

164. Nicoletti A, Caligiuri G, Paulsson G, Hansson GK. Functionality of specific immunity in atherosclerosis. Am Heart J. 1999;138:S438-43.

165. Wuttge DM, Romert A, Eriksson U, Törmä H, Hansson GK, Sirsjö A: Induction of CD36 by all-trans retinoic acid: Retinoic acid receptor signaling in the pathogenesis of atherosclerosis. FASEB J 15:1221-1223, 2001.

166. Zhou X, Nicoletti A, Elhage R, Hansson GK: Transfer of CD4+ T cells aggravates atherosclerosis in immuodeficient apoE knockout mice. Circulation 102:2919-2922, 2000.

167. Hansson GK: Inflammation, injury and atherosclerosis – The Russell Ross memorial lecture. In: Atherosclerosis XII, Proc XIIth Intl Symp on Atherosclerosis, eds S Stemme, AG Olsson, pp 53-66, Elsevier, Amsterdam 2000.

168. Valen G, Paulsson G, Bennet AM, Hansson GK, Vaage J: Gene Espression of Inflammatory Mediators in Different Chambers of the human heart. Ann Thorac Surg 70:562-567, 2000.

170 Hansson GK, Nilsson J: Pathogenesis of atherosclerosis. In: Cardiology. MH Crawford, JP DiMarco, eds. Pp 1.1-1.12. Mosby, London 2001.

171 Bian Z, Yan Z-q, Hansson GK, Thorén P, Normark S: Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice. J Infect Dis 183:612-619, 2001.

172 Daugherty A, Hansson GK: Lymphocytes in atherogenesis. In: Atherosclerosis. Gene Expression, Cell Interactions, and Oxidation. RT Dean, DT Kelly, editors. Pp 230-2492. Oxford University Press, Oxford 2000.

173 Hansson GK: The Stabilized Plaque: Will the Dream Come True? Eur Heart J 3:C69-C75, 2001.

174 Wuttge DM, Eriksson P, Sirsjö A, Hansson GK, Stemme S: Expression of interleukin-15 in mouse and human atherosclerotic lesions. Am J Pathol 159:417-423, 2001.

175 Valen G, Yan ZQ, Hansson GK: Nuclear Factor Kappa-B and the Heart. J Am Coll Cardiol. 38:307-314, 2001.

176 Hansson GK: Immune mechanisms in atherosclerosis. Arterioscl Thromb Vasc Biol 21:1876-1890, 2001.

177 Hansson GK: Cellular immune responses in atherosclerosis. In: Inflammatory Diseases of Blood Vessels. GS Hoffman, CM Weyand, eds. Pp. 155-173. Marcel Dekker, New York 2001.

178 Hansson GK: Immune aspects of atherosclerosis. Ann NY Acad Sci in press 2003.

179 Hansson GK: Immune Aspects of Atherosclerosis. In: Atherosclerosis and Autoimmunity. Shoenfeld Y, Harats D, Wick G, eds. Pp 17-25, Elsevier Science B.V., 2001.

180 Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ: Expression of Toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation. Circulation 105:1158-1161, 2002.

181 Caligiuri G, Nicoletti A, Poirier B, Hansson GK: Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J Clin Invest 109:745-753, 2002.

182 Hansson GK: The B cell: A good guy in vascular disease? Arterioscl Thromb Vasc Biol 22:523-524, 2002.

183 Yang R, Yan Z-q, Chen F, Hansson GK, Kiesesling R: Hyaluronic acid and chondroitin sulphate A rapidly promote differentiation of immature DC with upregulation of costimulatory and antigen-presenting molecules, and enhancement of NF-kappaB and protein kinase activity. Scand J Immunol 55:2-13, 2002.

184 Rolph MS, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson GK: Production of the long pentraxin PTX3 in advanced atherosclerotic plaques. Arterioscl Thromb Vasc Biol 22:e10-14, 2002.

185 Hansson GK, Libby P, Schönbeck U, Yan Z-Q: Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 91:281-291, 2002.

186 Schuster GU, Parini P, Wang L, Alberti S, Steffensen KR, Hansson GK, Angelin B, Gustafsson JÅ: Accumulation of foam cells in liver X receptor-deficient mice. Circulation 106:1147-1153, 2002.

187 Sirsjö A, Löfving A, Hansson GK, Wågsäter D, Tokuno S, Valen G: Deficiency of nitric oxide synthase 2 results in increased neointima formation in a mouse model of vascular injury. J Cardiovasc Pharmacol 41:897-902, 2003.

188 Caligiuri G, Rudling M, Ollivier V, Jacob M-P, Michel J-B, Hansson GK, Nicoletti A: Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice. Mol Med 9:10-17, 2003.

189 Elhage R, Jawien J, Rudling M, Ljunggren HG, Takeda K, Akira S, Bayard F, Hansson GK: Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice. Cardiovasc Res 59:234,240, 2003.

190 Erl W, Hristov M, Neureuter M, Yan ZQ, Hansson GK, Weber PC: HMGCoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells. Atherosclerosis 169:251-258, 2003.

191 Robertson AKL, Rudling M, Zhou X, Gorelik L, Flavell RA, Hansson GK: Disruption of TGF-β signalling in T cells accelerates atherosclerosis. J Clin Invest 112:1342-1350, 2003.

192 Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Juhani Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W Jr, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation. 2003 Oct 7;108(14):1664-72.

193 Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W Jr, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation. 2003;108(15):1772-8

194 Tupin E, Nicoletti A, Elhage R, Rudling M, Ljunggren HG, Hansson GK, Paulsson Berne G: CD1d-dependent activation of NKT cells aggravates atherosclerosis. J Exp Med, 2004;199:417-422.

195 Hansson GK: Detrimental and protective effects of adaptive immunity in atherosclerosis. Proc XIIIth Intl Symp Atherosclerosis, Elsevier, Amsterdam 2004.

196 Robertson AK, Zhou X, Strandvik B, Hansson GK: Th2 shift in severe hypercholesterolemia leads to strong IgE responses to an exogenous antigen. Scand J Immunol 2004; 59:285-293.

197 Wuttge DM, Zhou X, Sheikine Y, Wågsäter D, Stemme V, Hedin U, Stemme S, Hansson GK, Sirsjö A: CXCL16/SR-PSOX is an interferon-γ regulated chemokine and scavenger receptor expressed in atherosclerotic lesions. Arterioscl Thromb Vasc Biol 2004; 24:750-755.

198 Hemdahl AL, Falk E, Thorén P, Hansson GK: Thrombin inhibitor reduces myocardial infarction in apoE-/- x LDLR-/- mice. Am J Physiol 2004;287:H872-877.

199 Zhou X, Hansson GK: Vaccination and atherosclerosis. Curr Atheroscler Reports 2004;6:158-164.

200 Libby P, Hansson GK, Pober JS. Inflammation and immunity in atherogenesis. In: Chien KR, editor. Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease, 2nd edition. Philadelphia: Saunders;2004. p. 349-364.

201 Persson L, Boren J, Robertson AK, Wallenius V, Hansson GK, Pekna M.Lack of Complement Factor C3, but Not Factor B, Increases Hyperlipidemia and Atherosclerosis in Apolipoprotein E-/- Low-Density Lipoprotein Receptor-/- Mice. Arterioscler Thromb Vasc Biol. 2004, 24:1062-1067.

202 Zhou X, Hansson GK: Immunomodulation and vaccination for atherosclerosis. Expert Opin Biol Ther. 2004;4:599-612.

203 Sheikine Y, Hansson GK: Chemokines and atherosclerosis. Ann Med. 2004;36:98-118.

204 Zhou X, Hansson GK: Effect of sex and age on serum biochemical reference ranges in C57BL/6J mice. Comp Med. 2004;54:176-8.

205 Robertson AKL, Hansson GK: TGF-beta in atherosclerosis. Arterioscler Thromb Vasc Biol. 2004;24:e137-8.

206 Edfeldt K, Bennet AM, Eriksson P, Frostegard J, Wiman B, Hamsten A, Hansson GK, de Faire U, Yan ZQ: Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction. Eur Heart J. 2004;25:1447-53.

207 Nilsson J, Hansson GK, Shah PK: Immunomodulation of Atherosclerosis. Implications for Vaccine Development. Arterioscler Thromb Vasc Biol. 2005;25:18-28.

208 Hansson GK: Glimpse of the secret life of the plaque. Atheroscler Thromb Vasc Biol 2004;24:2203-4 (Editorial).

209 Chen F, Eriksson P, Hansson GK, Herzfeld I, Klein M, Hansson LO, Valen G. Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque. Int J Mol Med. 2005 Jan;15(1):57-65.

210 Hansson GK, Berne GP. Atherosclerosis and the immune system. Acta Paediatr Suppl. 2004 Dec;93(446):63-9.

211 Zhou X, Robertson AK, Rudling M, Parini P, Hansson GK. Lesion development and response to immunization reveal a complex role for CD4 in atherosclerosis. Circ Res 2005;96:427-34.

212 Hansson GK. ATVB In Focus: Immunity and Atherosclerosis. Arterioscler Thromb Vasc Biol 2005;25:17.

213 Olofsson PS, Jatta K, Wågsäter D, Gredmark S, Hedin U, Paulsson-Berne G, Söderberg-Nauclér C, Hansson GK, Sirsjö A. The antiviral cytomegalovirus-inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents. Arterioscler Thromb Vasc Biol 2005; 25:e113-6.

214 Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. Mechanisms of Disease. N Engl J Med 2005;352:1685-1695.

215 Hansson GK, Edfeldt K. Toll to be paid at the gateway to the vessel wall. Editorial. Arterioscler Thromb Vasc Biol 2005;25:1085-1087.

216 Lundberg GA, Kellin A, Samnegård A, Lundman P, Tornvall P, Dimmeler S, Zeiher AM, Hamsten A, Hansson GK, Eriksson P. Severity of coronary artery stenosis is associated with a polymorphism in the CXCL16/SR-PSOX gene. J Intern Med 2005;415-22.

217 Hemdahl AL, Caligiuri G, Hansson GK, Thoren P. Electrocardiographic characterization of stress-induced myocardial infarction in atherosclerotic mice. Acta Physiol Scand 2005;184:87-94.

218 Elhage R, Gourdy P, Jawien J, Brouchet L, Castano C, Fievet C, Hansson GK, Arnal JF, Bayard F. The Atheroprotective Effect of 17β-Estradiol Depends on Complex Interactions in Adaptive Immunity. Am J Pathol 2005;167:267-74.

219 de Graaf KL, Berne GP, Herrmann MM, Hansson GK, Olsson T, Weissert R. CDR3 sequence preference of TCRBV8S2(+) T cells within the CNS does not reflect single amino acid dependent avidity expansion. J Neuroimmunol 2005;166:47-54.

220 Pekna M, Persson L, Boren J, Nicoletti A, Hansson GK. Immunoglobulin treatment reduces atherosclerosis in apoE-/- LDLR-/- mice via the complement system. Clin Exp Immunol 2005;142:441-5.

221 Hallenbeck JM, Hansson GK, Becker KJ. Immunology of ischemic vascular disease: plaque to attack. Trends Immunol 2005;26:550-6

222 Hemdahl AL, Gabrielsen A, Zhu C, Eriksson P, Hedin U, Kastrup J, Thoren P, Hansson GK. Expression of Neutrophil Gelatinase-Associated Lipocalin in Atherosclerosis and Myocardial Infarction. Arterioscler Thromb Vasc Biol 2006;26:136-142.

223 Bäck M, Bu DX, Bränström R, Sheikine Y, Yan ZQ, Hansson GK. Leukotriene B4 signaling by means of NF-kB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Proc Natl Acad Sci USA 2005; 102:17501-6.

224 Sandberg WJ, Yndestad A, Oie E, Smith C, Ueland T, Ovchinnikova O, Robertson AK, Muller F, Semb AG, Scholz H, Andreassen AK, Gullestad L, Damas JK, Froland SS, Hansson GK, Halvorsen B, Aukrust P. Enhanced T-Cell Expression of RANK Ligand in Acute Coronary Syndrome. Possible Role in Plaque Destabilization. Arterioscler Thromb Vasc Biol. 2006;26:857-63.

225 Zhou X, Robertson AK, Hjerpe C, Hansson GK. Adoptive Transfer of CD4+ T Cells Reactive to Modified Low-Density Lipoprotein Aggravates Atherosclerosis. Arterioscl Thromb Vasc Biol 2006;26:864-70. 226 Wang Y, Gabrielsen A, Lawler PR, Paulsson-Berne G, Steinbruchel DA, Hansson GK, Kastrup J.: Myocardial gene expression of angiogenic factors in human chronic ischemic myocardium: influence of acute ischemia/cardioplegia and reperfusion. Microcirculation. 2006;13:187-97.

227 Tran PK, Agardh HE, Tran-Lundmark K, Ekstrand J, Roy J, Henderson B, Gabrielsen A, Hansson GK, Swedenborg J, Paulsson-Berne G, Hedin U. Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions. Atherosclerosis. 2007: 190:264-70

228 Ruusalepp A, Yan ZQ, Carlsen H, Czibik G, Hansson GK, Moskaug JO, Blomhoff R, Valen G. Gene deletion of NF-kappaB p105 enhances neointima formation in a mouse model of carotid artery injury. Cardiovasc Drugs Ther. 2006;20:103-11.

229 Ait-Oufella H, Salomon BL, Potteaux S, Robertson AK, Gourdy P, Zoll J, Merval R, Esposito B, Cohen JL, Fisson S, Flavell RA, Hansson GK, Klatzmann D, Tedgui A, Mallat Z. Natural regulatory T cells control the development of atherosclerosis in mice. Nature Med 2006;12:178-180.

230 Qiu H, Gabrielsen A, Agardh HE, Wan M, Wetterholm A, Wong CH, Hedin U, Swedenborg J, Hansson GK, Samuelsson B, Paulsson-Berne G, Haeggström J. Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. Proc Natl Acad Sci U S A 2006;103:8161-6.

231 Hansson GK, Robertson, AKL, Söderberg-Nauclér, C. Inflammation and atherosclerosis. Annual Review of Pathology 2006;1:297-329.

232 Hansson GK, Libby, P. The immune response in atherosclerosis: A double-edged sword. Nat Rev Immunol 2006;6:508-519.

233 Robertson AKL, Hansson GK. T cells in atherogenesis: for better or for worse? Arterioscler Thromb Vasc Biol 2006;26:2421-32.

234 Sheikine YA, Hansson GK. Chemokines as potential therapeutic targets in atherosclerosis. Curr Drug Targets 2006;7:13-27.

235 Hansson GK. Epidemiology complements immunology in the heart. Arterioscler Thromb Vasc Biol. 2006;26:2178-80.

236 Bäck M, Hansson GK. Leukotriene receptors in atherosclerosis. Ann Med 2006;38:493-502.

237 Smith C, Damas JK, Otterdal K, Oie E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation. J Am Coll Cardiol. 2006;48:1591-9.

238 Damås JK, Smith C, Øie E, Fevang B, Halvorsen B, Waehre T, Breland U, Yndestad A, Ovchinnikova O, Robertson AK, Sandberg WJ, Kjekshus J, Tasken K, Frøland SS, Gullestad L, Hansson GK, Quehenberger O, Aukrust P. Enhanced Expression of the Homeostatic Chemokines CCL19 and CCL21 in Clinical and Experimental Atherosclerosis. Possible Pathogenic Role in Plaque Destabilization. Arterioscler Thromb Vasc Biol 2007; 27:614-620.

239 Robertson AK, Hansson GK. Autoreactive CD4+CD28- T cells and acute coronary syndromes. Letter to the Editor. Arterioscler Thromb Vasc Biol 2007; 27:E19.

240 Gabrielsen A, Lawler PR, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-Berne G, Kastrup J, Hansson GK. Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium. J Mol Cell Cardiol 2007;42:870-83.

241 Hansson GK, Heistad DD. Two views on plaque rupture. Editorial. Arterioscler Thromb Vasc Biol 2007;27:697.

242 Bäck M, Sultan A, Ovchinnikova O, Hansson GK. 5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation. Circ Res 2007;100:946-949.

243 Hansson GK. LIGHT hits the liver. Science 2007;316:206-207.

244 Klingenberg R, Nofer J. R., Rudling M., Bea F., Blessing E., Preusch M., Grone H. J., Katus H. A., Hansson G. K., Dengler T. J. Sphingosine-1-Phosphate Analogue FTY720 Causes Lymphocyte Redistribution and Hypercholesterolemia in ApoE-Deficient Mice. Arterioscler Thromb Vasc Biol 2007; 27:2392-2399.

245 Yan ZQ, Hansson GK. Innate immunity, macrophage activation, and atherosclerosis. Immunol Rev 2007:219:187-203.

246 Olofsson PS, Söderström LÅ, Wågsäter D, Sheikine Y, Ocaya P, Lang F, Rabu C, Chen L, Rudling M, Aukrust P, Hedin U, Paulsson-Berne G, Sirsjö A, Hansson GK: CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation 2008; 117:1292-1301.

247 Breland UM, Halvorsen B, Hol J, Oie E, Paulsson-Berne G, Yndestad A, Smith C, Otterdal K, Hedin U, Waehre T, Sandberg WJ, Froland SS, Haraldsen G, Gullestad L, Damås JK, Hansson GK, Aukrust P: A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins. Arterioscl Thromb Vasc Biol 2008; 28:005-1011.

248 Hansson GK, Nilsson J: Atherosclerosis as inflammation: a controversial concept becomes accepted. J Intern Med 2008; 263:462-463.

249 Nilsson J, Hansson GK: Autoimmunity in atherosclerosis: a protective response losing control? J Intern Med 2008; 263:464-478.

250 Jawien J, Bian Z, Sheikine Y, Olofsson PS, Pang Y, Edholm T, Dou Y, Metzger D, Hellström PM, Feil R, Hansson GK: Abrogation of mitochondrial transcription in smooth muscle cells impairs smooth muscle contractility and vascular tone. J Physiol Pharmacol. 2008;59:239-52.

251 Schaufelberger C, Andersson R, Nordborg E, Hansson GK, Nordborg C, Wahlstrom J. An uneven expression of T cell receptor V genes in the arterial wall and peripheral blood in giant cell arteritis. Inflammation. 2008;31:372-383.

252 Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Circ Res. 2009;104:60-68.

253 Hansson GK: Atherosclerosis – An immune disease. The Anitschkov Lecture 2007. Atherosclerosis 2009; 202:2-10.

254 Olofsson PS, Söderström LÅ, Jern C, Sirsjö A, Ria M, Sundler E, de Faire U, Wiklund PG, Öhrvik J, Hedin U, Paulsson-Berne G, Hamsten A, Eriksson P, Hansson GK: Genetic variants of TNFSF4 and risk for carotid artery disease and stroke. J Mol Med 2009; 87:337-46.

255 Zhou X, Johnston TP, Johansson D, Parini P, Funa K, Svensson J, Hansson GK. Hypercholesterolemia leads to elevated TGF-beta1 activity and T helper 3-dependent autoimmune responses in atherosclerotic mice. Atherosclerosis 2009; 204:381-387.

256 Ovchinnikova, O., Robertson, A.K., Wagsater, D., Folco, E.J., Hyry, M., Myllyharju, J., Eriksson, P., Libby, P., and Hansson, G.K. T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. Am J Pathol 2009;174:693-700.

257 Sultan, A., Strodthoff, D., Robertson, A.K., Berne, G.P., Fauconnier, J., Parini, P., Ryden, M., Thierry-Mieg, N., Johansson, M.E., Chibalin, A.V., Zierath JR, Arner P, Hansson GK. T Cell-Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Mice. Circ Res 2009; 104:961-8.

258 Sandberg WJ, Otterdal K, Gullestad L, Halvorsen B, Ragnarsson A, Fröland SS, Damås JK, Aukrust P, Hansson GK, Yndestad A. The tumor necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis. Thromb Haemost 2009; 102:704-710.

259 Libby P, Ridker PM, Hansson GK. Inflammation in Atherosclerosis: From Pathophysiology to Practice. J Am Coll Cardiol, 2009;54:2129-2138.

260 Ovchinnikova O, Gylfe Å, Bailey L, Nordström A, Rudling M, Jung C, Bergström S, Waldenström A, Hansson GK, Nordström P. Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of apoe deficient mice. Arterioscl Thromb Vasc Biol 2009; 29:1478-1480.

261 Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg WJ, Berne GP, Pedersen TM, Folkersen L, Gullestad L, Øie E, Hansson GK, Aukrust P. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscl Thromb Vasc Biol 2009; 29:1228-1234.

262 Hansson GK, Nilsson J. Vaccination against atherosclerosis? Induction of atheroprotective immunity. Sem Immunopathol 2009; 31:95-101.

263 Cao Z, Icli B, Wara AK, Packard R, Esen F, Stapleton CJ, Subramaniam M, Kretschmer K, Apostolou I, von Boehmer H, Hansson GK, Spelsberg TC, Libby P, Feinberg MW. Kruppel-like factor KLF10 targets TGF-beta1 to regulate CD4+CD25- T cells and T regulatory cells. J Biol Chem 2009; 284:24914-24924.

264 Diez D, Wheelock ÅM, Goto S, Haeggström JZ, Paulsson-Berne G, Hansson GK, Hedin U, Gabrielsen A, Wheelock CE. The use of network analyses for elucidating mechanisms in cardiovascular disease. Mol. BioSyst. 2010; 6: 289–304.

265 Hansson GK. Inflammatory mechanisms in atherosclerosis. J Thromb Haemost 2009;7 Suppl 1:328-331.

266 Lundberg AM, Hansson GK. Innate immune signals in atherosclerosis. Clin Immunol 2010;134:5-24

267 Andersson J, Libby P, Hansson GK. Adaptive immunity and atherosclerosis. Clin Immunol 2010;134:33-46.

268 Hjerpe C, Johansson D, Hermansson A, Hansson GK, Zhou X. Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe(-/-) mice. Atherosclerosis. 2010;209:436-441.

269 Klingenberg R, Hansson GK. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur Heart J. 2009 30:2838-44.

270 Hansson GK, Jonasson L. The discovery of cellular immunity in the atherosclerotic plaque. Arterioscler Thromb Vasc Biol. 2009;29:1714-7.

271 Hansson GK. Inflammatory mechanisms in atherosclerosis. J Thromb Haemost. 2009;7 Suppl 1:328-31.

272 Roncal C, Buysschaert I, Gerdes N, Georgiadou M, Ovchinnikova O, Fischer C, Stassen JM, Moons L, Collen D, De Bock K, Hansson GK, Carmeliet P. Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions. Cardiovasc Res. 2010; 86:29-36.

273 Breland UM, Michelsen AE, Skjelland M, Folkersen L, Krohg-Sorensen K, Russell D, Ueland T, Yndestad A, Paulsson-Berne G, Damås JK, Oie E, Hansson GK, Halvorsen B, Aukrust P. Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation. Cardiovasc Res. 2010; 86:265-273.

274 Klingenberg R, Lebens M, Hermansson A, Fredrikson GN, Strodthoff D, Rudling M, Ketelhuth DF, Gerdes N, Holmgren J, Nilsson J, Hansson GK. Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis. Arterioscler Thromb Vasc Biol. 2010; 30:946-952.

275 Hermansson A, Ketelhuth DFJ, Strodthoff D, Wurm M, Hansson EM, Nicoletti A, Paulsson-Berne G, Hansson GK. Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis. J Exp Med 2010; 207:1081-1093.

276 Gabrielsen A, Qiu H, Bäck M, Hamberg M, Hemdahl AL, Agardh H, Folkersen L, Swedenborg J, Hedin U, Paulsson-Berne G, Haeggström JZ, Hansson GK. Thromboxane synthase expression and thromboxane A(2) production in the atherosclerotic lesion. J Mol Med 2010; 88:795-806.

277 Folkersen L, van´t Hooft F, Chernogubova E, Agardh HE, Hansson GK, Hedin U, Liska J, Syvänen AC, Paulsson-Berne G, Franco-Cereceda A, Hamsten A, Gabrielsen A, Eriksson P, on behalf of the BiKE and ASAP study groups. Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease. Circ Cardiovasc Genet 2010 Aug;3(4):365-73.

278 Hansson GK, Björkholm M. Tackling two diseases with HDL. Science 2010;328:1641-2.

279 Sheikine Y, Deodato B, Olofsson PS, Söderström LA, Lundberg AM, Bodin I, Rudling M, Theodorsson E, Hansson GK. Activation of VPAC(1) receptors aggravates early atherosclerosis in hypercholesterolemic apolipoprotein E-deficient mice. Biochem Biophys Res Commun. 2010; 402:471-476.

280 Hermansson A, Johansson DK, Ketelhuth DFJ, Andersson J, Zhou X, Hansson GK. Immunotherapy with tolerogenic apolipoprotein B-100 loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice. Circulation 2011; 123:1083-1091.

281 Gertow, K., E. Nobili, L. Folkersen, J.W. Newman, T.L. Pedersen, J. Ekstrand, J. Swedenborg, G. Paulsson-Berne, H. Kühn, C.E. Wheelock, G.K. Hansson, U. Hedin, J.Z. Haeggstrom, and A. Gabrielsen. 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis 2011; 215:411-6.

282 Hansson GK, Lundberg AM. Toll in the vessel wall – for better or worse? Proc Natl Acad Sci USA 2011; 108:2637-2638.

283 Hansson GK, Hermansson A. The immune system in atherosclerosis. Nat Immunol. 2011;12:204-212.

284 Nagy E, Andersson DC, Caidahl K, Eriksson MJ, Eriksson P, Franco-Cereceda A, Hansson GK, Bäck M. Upregulation of the 5-lipoxygenase pathway in human aortic valves correlates with severity of stenosis and leads to leukotriene-induced effects on valvular myofibroblasts. Circulation 2011;123:1316-25.

285 Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature 2011; 473:317-325.

286 Razuvaev A, Ekstrand J, Folkersen L, Marcus D, Swedenborg J, Hansson GK, Gabrielsen A, Paulsson-Berne G, Roy J, Hedin U. Correlations between clinical variables and gene expression profiles in carotid plaque instability. Eur J Vasc Endovasc Surg 2011; 42:722-730.

287 Gerdes N, Zhu L, Ersoy M, Hermansson A, Hjemdahl P, Hu H, Hansson GK, Li N. Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans. Thromb Haemost. 2011;106:353-362.

288 Hansson GK, Klareskog L. Cooling down the inflammasome. Nature Med 2011; 17:790-791.

289 Levin MC, Jirholt P, Wramstedt A, Johansson ME, Lundberg AM, Gustafsson Trajkovska M, Stahlman M, Fogelstrand P, Brisslert M, Fogelstrand L, Yan ZQ, Hansson GK, Bjorkbacka H, Olofsson SO, Boren J. Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation. Circ Res. 2011; 109:1210-8.

290 Medzhitov R, Shevach EM, Trinchieri G, Mellor AL, Munn DH, Gordon S, Libby P, Hansson GK, Shortman K, Dong C, Gabrilovich D, Gabrysova L, Howes A, O'Garra A. Highlights of 10 years of immunology in nature reviews immunology. Nat Rev Immunol. 2011;11:693-702.

291 Ketelhuth DF, Rios FJ, Wang Y, Liu H, Johansson ME, Fredrikson GN, Hedin U, Gidlund M, Nilsson J, Hansson GK, Yan ZQ. Identification of a danger-associated peptide from apolipoprotein B100 (ApoBDS-1) that triggers innate proatherogenic responses. Circulation. 2011;124:2433-2443.

292 Hansson GK, Hamsten A. Atherosclerosis, thrombosis and vascular biology. In: Cecil Medicine, 24th Ed. L Goldman, AI Schafer. Ch 70. Pp 409-412 + e-supplement. Elsevier-Saunders, Philadelphia 2011.

293 Ketelhuth DF, Hansson GK. Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall. Thromb Haemost. 2011;106:779-86.

294 Folkersen L, Persson J, Ekstrand J, Agardh HE, Hansson GK, Gabrielsen A, Hedin U, Paulsson-Berne G. Prediction of ischemic events based on transcriptomic and genomic profiling in patients undergoing carotid endarterectomy. Mol Med 2012; 18:669-675.

295 Zhang L, Ovchinnikova A, Jönsson A, Lundberg AM, Berg M, Hansson GK, Ketelhuth DFJ. The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice. Eur Heart J 2012; 33:2025-2034.

296 Salagianni M, Galani I, Lundberg AM, Davos CH, Varela A, Gavriil A, Lyytikainen LP, Lehtimäki T, Sigala F, Folkersen L, Gorgoulis V, Lenglet S, Montecucco F, Mach F, Hedin U, Hansson GK, Monaco C, Andreakos E. Toll-like receptor 7 protects from atherosclerosis by constraining “inflammatory” macrophage activation. Circulation 2012; 126:952-962.

297 Nobili E, Salvado-Duro S, Folkersen L, Castiglioni L, Kastrup J, Wetterholm A, Tremoli E, Hansson GK, Sironi L, Haeggström JZ, Gabrielsen A. Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease. PLoS One 2012; 7:e41786.

298 Smedbakken LM; Halvorsen B; Daissormont I; Ranheim T; Michelsen AE, Skjelland M, Lund Sagesen E, Folkersen L, Krohhg-Sorensen K, Russell D, Holm S, Ueland T, Fevang B, Hedin U, Yndestad A, Gullestad L, Hansson GK, Biessen EA, Aukrust P. Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis -potential role in plaque stabilization. Atherosclerosis 2012; 224:266-273.

299 Klingenberg, R., Ketelhuth, D.F., Strodthoff, D., Gregori, S., and Hansson, G.K. Subcutaneous immunization with heat shock protein-65 reduces atherosclerosis in Apoe(-/-) mice. Immunobiology 2012; 217:540-547.

300 Hansson, G.K. 2012. How to chew up cells: lessons for the atherosclerotic plaque. Circ Res 111:669-671.

301 Elhage, R., Ljunggren, H.G., and Hansson, G.K. 2012. Proatherogenic role of interleukin-18: effects on inflammation and action on vascular cells. Cardiovascular Research 2012; 96:176-180.

302 Gertow K, Sennblad B, Strawbridge RJ, Ohrvik J, Zabaneh D, Shah S, Veglia F, Fava C, Kavousi M, McLachlan S, Kivimäki M, Bolton JL, Folkersen L, Gigante B, Leander K, Vikström M, Larsson M, Silveira A, Deanfield J, Voight BF, Fontanillas P, Sabater-Lleal M, Colombo GI, Kumari M, Langenberg C, Wareham NJ, Uitterlinden AG, Gabrielsen A, Hedin U, Franco-Cereceda A, Nyyssönen K, Rauramaa R, Tuomainen TP, Savonen K, Smit AJ, Giral P, Mannarino E, Robertson CM, Talmud PJ, Hedblad B, Hofman A, Erdmann J, Reilly MP, O'Donnell CJ, Farrall M, Clarke R, Franzosi MG, Seedorf U, Syvänen AC, Hansson GK, Eriksson P, Samani NJ, Watkins H, Price JF, Hingorani AD, Melander O, Witteman JC, Baldassarre D, Tremoli E, de Faire U, Humphries SE, Hamsten A. Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk. Circ Cardiovasc Genet 2012; 5:656-665.

303 Subramanian, M., Thorp, E., Hansson, G. K., Tabas, I. Treg-mediated suppression of atherosclerosis requires MYD88 signaling in dendritic cells. J Clin Invest 2013; 179-188.

304 Agardh H, Gertow K, Salvado D, van Puijvelde K, Hermansson A, Hansson GK, Paulsson Berne G, Gabrielsen A: Fatty acid binding protein 4 in circulating leukocytes reflects atherosclerotic lesion progression in Apoe-/- mice. J Cell Mol Med 2013; 17:303-310.

305 Hansson GK. Immunity to low-density lipoprotein. In: Inflammation and Atherosclerosis. G Wick, C Grundtman, editors. Wien: Springer-Verlag 2012, pp 423-434.

306 Klingenberg, R., Gerdes, N., Badeau, R.M., Strodthoff, D., Lohmann, C., Gisterå, A., Ketelhuth, D.F.J., Lundberg, A.M., Lüscher, T.F., Jauhiainen, M., Sparwasser, T., Hansson, G.K. Selective depletion of Foxp3+ regulatory T cells promotes hypercholesterolemia and exacerbates experimental atherosclerosis. J. Clin. Invest 2013; 123:1323-1334.

307 Lundberg AM, Ketelhuth DF, Johansson ME, Gerdes N, Liu S, Yamamoto M, Akira S, Hansson GK. Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis. Cardiovasc Res 2013; 99:364-373.

308 Ketelhuth DF, Gisterå A, Johansson DK, Hansson GK. T cell-based therapies for atherosclerosis. Curr Pharm Des 2013; 9:5850-8.

309 Nagy E, Eriksson P, Yousry M, Caidahl K, Ingelsson E, Hansson GK, Franco-Cereceda A, Bäck M. Valvular osteoclasts in calcification and aortic valve stenosis severity. Int J Cardiol 2013; 168:2264-71.

310 Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N. Lack of Invariant Natural Killer T Cells Affects Lipid Metabolism in Adipose Tissue of Diet-Induced Obese Mice. Arterioscler Thromb Vasc Biol 2013; 33:1189-1196.

311 Paramel GV, Folkersen L, Strawbridge RJ, Elmabsout AA, Särndahl E, Lundman P, Jansson JH, Hansson GK, Sirsjö A, Fransén K. The CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation. Clin Sci (Lond). 2013; 125:401-407.

312 Gisterå A, Robertson AK, Andersson J, Ketelhuth DFJ, Ovchinnikova O, Nilsson SK, Lundberg AM, Li MO, Flavell RA, Hansson GK. Transforming growth factor-β signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17 dependent pathway. Science Transl Med 2013; 5:101-109.

313 Libby P, Lichtman AH, Hansson GK. Immune effector mechanisms implicated in atherosclerosis: from mice to humans. Immunity 2013; 38:1092-1104.

314 Liu HQ, Zhang XY, Edfeldt K, Nijhuis MO, Idborg H, Bäck M, Roy J, Hedin U, Jakobsson PJ, Laman JD, de Kleijn DP, Pasterkamp G, Hansson GK, Yan ZQ. Identification of NOD2 as a novel innate immune signal that induces the PGE2 pathway in atherosclerosis. Arterioscler Thromb Vasc Biol 2013; 33:2193-2201.

315 Hansson GK.The heroic era of cardiac care. Nature Med 2013;19:963.

316 Ovchinnikova OA, Berge N, Kang C, Urien C, Ketelhuth DFJ, Pottier J, Drouet L, Hansson GK, Marchal G, Bäck M, Schwartz-Cornil I, Lagranderie M. Mycobacterium bovis BCG killed by extended freeze-drying induces an immunoregulatory profile and protects against atherosclerosis. J Int Med 2014; 275:49-58.

Ovchinnikova OA, Folkersen L, Persson J, Lindeman JHN, Ueland T, Aukrust P, Gavrisheva N, Shlyakhto E, Paulsson-Berne G, Hedin U, Olofsson PS, Hansson GK. The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions. J Int Med. 276:525-536, 2014.

322. Assinger A, Wang Y, Butler LM, Hansson GK, Yan ZQ, Söderberg-Nauclér C, Ketelhuth DF. Aoplipoprotein B100 danger-associated signal 1 (ApoBDS-1) triggers platelet activation and boosts platelet-leukocyte proinflammatory responses. Thromb Haemost. 112:332-341, 2014.

323. Zhu L, Huang Z, Stålesen R, Hansson GK, Li N. Platelets provoke distinct dynamies of immune responses by differentially regulating CD4+-T-cell proliferation. J Thromb Haemost. 12:1156-165, 2014.

324. Söderström LÅ, Gertow K, Folkersen L, Sabater-Lleal M, Sundman E, Sheikine Y, Goel A, Baldassarre D, Humphries SE, de Faire U, Watkins H, Tremoli E, Veglia F, Hamsten A, Hansson GK, Olofsson PS. Human genetic evidence for involvement of CD137 in atherosclerosis. Mol Med. 20:456-465, 2014.

325. Johansson ME, Zhang XY, Edfelt K, Lundberg AM, Levin MC, Borén J, Li W, Yuan X-M, Folkersen L, Eriksson P, Hedin U, Low H, Sviridov D, Rios FJ, Hansson GK, Yan ZQ. Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice. Eur J Immunol. 44: 3081-392, 2014.

326. Sage AP, Murphy D, Maffia P, Masters LM, Sabir SR, Baker LL, Cambrook H, Finigan AJ, Ait-Oufella H, Grassia G, Harrison JE, Ludewig B, Reith W, Hansson GK, Reizis B, Hugues S, Mallat Z. MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity. Ciculation.130: 1363-1373, 2014.

327. Johansson ME, Ulleryd MA, Bernardi A, Lundberg AM, Andersson A, Folkersen L, Fogelstrand L, Islander U, Yan ZQ, Hansson GK. a7 Nicotinic acetylcholine receptor is expressed in human atherosclerosis and inhibits disease in mice. Brief report. Arterioscler Thromb Vasc Biology. 34: 2632-2636, 2014.

328. Hansson GK. A journey in science: medical scientist in translation. Mol Med. 20: 381-389, 2014.

329. Petri MH, Laguna-Fernández A, Gonzalez-Diez M, Paulsson-Berne G, Hansson GK, Bäck M. The role of the FPR2/ALX receptor in atherosclerosis development and plaque stability. Cardiovasc Res. 105: 65-74, 2015.

330. Libby P, Hansson GK. Inflammation and immunity in diseases of the arterial tree: Players and layers. Review. Circ Res.116: 307-311, 2015.

331. Hansson GK. How to repeat a success and control bad influence (Editorial). Circulation. 131:525-527, 2015.

332. Hansson GK. At its heart, homeostasis is about T cells (Editorial). J Amer Coll Cardiol. 65: 1187-1189, 2015.

333. Bäck M, Hansson GK. Anti-inflammatory therapies for atherosclerosis. Review, Nat. Rev. Cardiol. 12: 199-211, 2015.

334. Polyzos K.A, Ovchinnikova O, Berg M, Baumgartner R, Agardh H, Pirault J, Gisterå A, Assinger A, Laguna-Fernandez A, Bäck M, Hansson G,K, Ketelhuth D.F.J. Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe-/- mice. Cardiovasc Res. 106: 295-302, 2015.

335. Ketelhuth D. F.J. Hansson G.K. Modulation of autoimmunity and atherosclerosis – Common targets and promising translational approaches against disease. Review. Circ J. 79: 924-933, 2015.

336. Grasset E.K, Duhlin A, Agardh H.E, Ovchinnikova O, Hägglöf T, Forsell M.N, Paulsson-Berne G, Hansson G.K, Ketelhuth D.F.J, Karlsson M.C.I. Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response. Proc Natl Acad Sci USA 2015;112:E2030-8, 2015 (PMID: 25848033) .

337. Strodthoff D, Ma Z, Wirström T, Strawbridge RJ, Ketelhuth DF, Engel D, Clarke R, Falkmer S, Hamsten A, Hansson GK, Björklund A, Lundberg AM. Toll-like receptor 3 influences glucose homeostasis and β-cell insulin secretion. Diabetes 2015; 64:3425-6438 (PMID: 25918231).

338. Hansson GK, Libby P, Tabas I. Inflammation and plaque vulnerability. J Int Med 2015; 483-493 (PMID: 26260307).

339. Nilsson J, Hansson GK. The changing face of atherosclerotic plaque inflammation. J Intern Med 2015; 278:430-432.

340. Spitz C, Winkels H, Bürger C, Weber C, Lutgens E, Hansson GK, Gerdes N. Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential. Cell Mol Life Sci. 2016 Mar;73:901-22.

341. Centa M, Gruber S, Nilsson D, Polyzos KA, Johansson DK, Hansson GK, Ketelhuth DF, Binder CJ, Malin S. Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene. Arterioscler Thromb Vasc Biol. 2016 Jan;36:25-36.

342. Perisic L, Aldi S, Sun Y, Folkersen L, Razuvaev A, Roy J, Lengquist M, Åkesson S, Wheelock CE, Maegdefessel L, Gabrielsen A, Odeberg J, Hansson GK, Paulsson-Berne G, Hedin U. Gene expression signatures, pathways and networks in carotid atherosclerosis. J Intern Med. 2016 Mar;279:293-308.

343. Ketelhuth DF, Hansson GK. Adaptive Response of T and B Cells in Atherosclerosis. Circ Res. 2016 Feb 19;118:668-78.

344. Claesson-Welsh L, Hansson GK; Royal Swedish Academy of Sciences. Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns. Lancet. 2016 Feb 23;387:942.

345. Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A. NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis. J Am Heart Assoc. 2016 May 20;5(5). pii: e003031. doi: 10.1161/JAHA. 115.003031.

346. Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Sci Rep. 2016 Jun 22; 6:28337. doi: 10.1038/srep28337.

347. Perisic Matic L, Rykaczewska U, Razuvaev A, Sabater-Lleal M, Lengquist M, Miller CL, Ericsson I, Röhl S, Kronqvist M, Aldi S, Magné J, Paloschi V, Vesterlund M, Li Y, Jin H, Diez MG, Roy J, Baldassarre D, Veglia F, Humphries SE, de Faire U, Tremoli E, Odeberg J, Vukojević V, Lehtiö J, Maegdefessel L, Ehrenborg E, Paulsson-Berne G, Hansson GK, Lindeman JH, Eriksson P, Quertermous T, Hamsten A, Hedin U. Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. Arterioscler Thromb Vasc Biol. 2016;36:1947-61. doi: 10.1161/ATVBAHA.116.307893.

348. Karadimou G, Folkersen L, Berg M, Perisic L, Discacciati A, Roy J, Hansson GK, Persson J, Paulsson-Berne G. Low TLR7 gene expression in atherosclerotic plaques is associated with major adverse cardio- and cerebrovascular events. Cardiovasc Res. 2017; 113:30-39. doi: 10.1093/cvr/cvw231. PMID: 2786431

349. Eken SM, Jin H, Chernogubova E, Li Y, Simon N, Sun C, Korzunowicz G, Busch A, Bäcklund A, Österholm C, Razuvaev A, Renné T, Eckstein HH, Pelisek J, Eriksson P, González Díez M, Perisic Matic L, Schellinger IN, Raaz U, Leeper NJ, Hansson GK, Paulsson-Berne G, Hedin U, Maegdefessel L. MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions. Circ Res 2017; 120:633-644. . DOI 10.1161 /CIRCRESAHA. 116.309318. PMID: 27895035.

350. Petri MH, Laguna-Fernandez A, Arnardottir H, Wheelock CE, Perretti M, Hansson GK, Bäck M. Aspirin-triggered lipoxin A4 inhibits atherosclerosis progression in apolipoprotein E-/- mice. Br J Pharmacol. 2017; 174:4043-4054. doi: 10.1111/bph.13707. PMID: 28071789.

351. Gisterå A, Hermansson A, Strodthoff D, Klement ML, Hedin U, Fredrikson GN, Nilsson J, Hansson GK, Ketelhuth DF. Vaccination against T-cell epitopes of native ApoB100 reduces vascular inflammation and disease in a humanized mouse model of atherosclerosis. J Intern Med. 2017; 281:383-397. doi: 10.1111/joim.12589. PMID: 28194913.

352. Gisterå A, Hansson GK. The immunology of atherosclerosis. Nat Rev Nephrol. 2017; 13:368-380. doi: 10.1038/nrneph.2017.51. PMID: 28392564.

353. Mailer RKW, Gisterå A, Polyzos KA, Ketelhuth DFJ, Hansson GK. Hypercholesterolemia Induces Differentiation of Regulatory T Cells in the Liver. Circ Res. 2017; 120:1740-1753. d10.1161/CIRCRESAHA.116.310054. PMID: 28420668.

354. Nagy E, Lei Y, Martínez-Martínez E, Body SC, Schlotter F, Creager M, Assmann A, Khabbaz K, Libby P, Hansson GK, Aikawa E. Interferon-γ Released by Activated CD8+ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves. Am J Pathol. 2017; 187:1413-1425. doi: 10.1016/j.ajpath.2017.02.012. PMID: 28431214.

355. Pirault J, Polyzos KA, Petri MH, Ketelhuth DFJ, Bäck M, Hansson GK. The inflammatory cytokine interferon-gamma inhibits sortilin-1 expression in hepatocytes via the JAK/STAT pathway. Eur J Immunol. 2017; 47:1918-1924. doi: 10.1002/eji.201646768. PMID: 28742217.

356. Söderström LÅ, Jin H, Caravaca AS, Klement ML, Li Y, Gisterå A, Hedin U, Maegdefessel L, Hansson GK, Olofsson PS. Increased Carotid Artery Lesion Inflammation Upon Treatment With the CD137 Agonistic Antibody 2A. Circ J. 2017 Nov 24;81(12):1945-1952. doi: 10.1253/circj.CJ-17-0230. Epub 2017 Jul 26. PMID: 28747613

357. Hansson GK. Inflammation and Atherosclerosis - The End of a Controversy. Circulation. 2017; 136:1875-1877. doi:10.1161/CIRCULATIONAHA.117.030484. PMID: 28916641.

358. Brauner S, Jiang X, Thorlacius GE, Lundberg AM, Östberg T, Yan ZQ, Kuchroo VK, Hansson GK, Wahren-Herlenius M. Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content. Cardiovasc Res. 2018 Jan 1;114(1):158-167. doi: 10.1093/cvr/cvx181. PMID: 29016728

359. Lundberg AK, Jonasson L, Hansson GK, Mailer RKW. Activation-induced FOXP3 isoform profile in peripheral CD4+ T cells is associated with coronary artery disease. Atherosclerosis. 2017; 267:27-33. doi: 10.1016/j.atherosclerosis.2017.10.026. PMID: 29100058.

360. Mailer RKW, Gisterå A, Polyzos KA, Ketelhuth DFJ, Hansson GK. Hypercholesterolemia Enhances T Cell Receptor Signaling and Increases the Regulatory T Cell Population. Sci Rep. 2017 Nov 15;7(1):15655. doi: 10.1038/s41598-017-15546-8. PMID: 29142309.

361. Bäck M, Ketelhuth DFJ, Malin S, Olofsson PS, Paulsson-Berne G, Yan ZQ, Hansson GK. Immune-Mediated Mechanisms of Atherosclerosis. In: Encyclopedia of Cardiovascular Research and Medicine, vol.3, pp. 68-76. Elsevier, Oxford 2018.

362. Libby P, Hansson GK. Adaptive immunity in acute coronary syndromes: chicken or egg? Eur Heart J. 2018 Apr 1;39(13):1098-1099. doi: 10.1093/eurheartj/ehx743. PMID: 29315374

363. Libby P, Hansson GK. Taming Immune and Inflammatory Responses to Treat Atherosclerosis. J Am Coll Cardiol. 2018 Jan 16;71(2):173-176. doi: 10.1016/j.jacc.2017.10.081. PMID: 29325641

364. Joly AL, Seitz C, Liu S, Kuznetsov NV, Gertow K, Westerberg LS, Paulsson-Berne G, Hansson GK, Andersson J. Alternative Splicing of FOXP3 Controls Regulatory T Cell Effector Functions and Is Associated With Human Atherosclerotic Plaque Stability. Circ Res. 2018 May 11;122(10):1385-1394. doi: 10.1161/CIRCRESAHA.117.312340. PMID: 29618596.

365. Hansson GK. Alfred Nobel's 1895 will is strictly upheld to this day. Nature. 2018 Apr 5;556:31. doi: 10.1038/d41586-018-04050-2. PMID: 29620758

366. Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X, Andonova T, Walker ME, Dalli J, Arnardottir H, Gisterå A, Thul S, Wheelock CE, Paulsson-Berne G, Ketelhuth DFJ, Hansson GK, Bäck M. ERV1/ChemR23 Signaling Protects from Atherosclerosis by Modifying oxLDL Uptake and Phagocytosis in Macrophages. Circulation. 2018; 138:1693-1705. doi: 10.1161/CIRCULATIONAHA.117.032801.

367. Wilhelmson AS, Lantero Rodriguez M, Svedlund Eriksson E, Johansson I, Fogelstrand P, Stubelius A, Lindgren S, Fagman JB, Hansson GK, Carlsten H, Karlsson MCI, Ekwall O, Tivesten Å. Testosterone Protects Against Atherosclerosis in Male Mice by Targeting Thymic Epithelial Cells-Brief Report. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1519-1527. doi: 10.1161/ATVBAHA.118.311252. Epub 2018 May 31. PMID: 29853568

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375. Eken SM, Christersdottir T, Winski G, Sangsuwan T, Jin H, Chernogubova E, Pirault J, Sun C, Simon N, Winter H, Backlund A, Haghdoost S, Hansson GK, Halle M, Maegdefessel L. miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease. JACC Basic Transl Sci. 2019; 4:72-82. doi: 10.1016/j.jacbts.2018.10.006

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