Belinda Bullard - Selected Publications#

Stronczek C, Lange S, Bullard B, Wolniak S, Börgeson E, Mayans O, Fleming JR. The N2A region of titin has a unique structural configuration. J Gen Physiol. 2021 Jul 5;153(7):e202012766. doi: 10.1085/jgp.202012766.

Zhou T, Fleming JR, Lange S, Hessel AL, Bogomolovas J, Stronczek C, Grundei D, Ghassemian M, Biju A, Börgeson E, Bullard B, Linke WA, Chen J, Kovermann M, Mayans O. Molecular characterisation of titin N2A and its binding of CARP reveals a titin/actin cross-linking mechanism. J Mol Biol. 2021 Feb 26:166901. doi: 10.1016/j.jmb.2021.166901.

Bullard, B and Pastore, A (2019). Through thick and thin: dual regulation in insect flight muscle and cardiac muscle compared. J. Muscle Res. and Cell Motil. 40, 99-110.

Sanfelice, D., Sanz-Hernandez, M., de Simone, A., Bullard, B. and Pastore, A. (2016). Towards understanding the molecular basis of stretch activation: a structural comparison of the two troponin C isoforms of Lethocerus. J. Biol. Chem. 291, 16090-16099.

Bogomolovas, J., Fleming, JR., Anderson, BR., Williams, R., Lange, S., Simon, B., Khan, MM., Rudolf, R., Franke, B., Bullard, B., Rigden, DJ., Granzier, H., Labeit, S. and Mayans, O. (2016). Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin’s I-band: the cardiomyopathy-linked mutation T25801. Open Biol. 6, 160114.

Katzemich, A., West, R. H., Fukuzawa, A., Sweeney, S.T., Gautel, M., Sparrow, J. and Bullard, B. (2015). Binding partners of the kinase domains of Drosophila obscurin and their effect on the structure of the flight muscle. J. Cell Sci. 128, 3386-3397.

Orfanos, Z., Leonard, K., Elliott, C., Katzemich, A., Bullard, B and Sparrow, J. (2015). Sallimus and the dynamics of sarcomere assembly in insect flight muscle. J. Molec. Biol. (2015). Sallimus and the dynamics of sarcomere assembly in insect flight muscle. J. Mol. Biol. 427, 2151-2158.

Katzemich, A., Kreisköther, N., Alexandrovich , A., Elliott, C., Schöck, F., Leonard, K., Sparrow, J. and Bullard, B. (2012). The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila. J. Cell Sci. 125, 3367-3379.

Krzic, U., Rybin, V., Leonard, K.R., Linke,W.A. and Bullard, B. (2010). Regulation of oscillatory contraction in insect flight muscle by troponin. J. Mol. Biol. 397, 110-118.

Past contributions

Burkart, C., Qiu, F., Brendel, S., Benes, V., Hååg, P., Labeit, S., Leonard, K. and Bullard, B. (2007). Modular proteins from the Drosophila sallimus (sls) gene and their expression in muscles with different extensibility. J. Mol. Biol. 367, 953-969

Bullard, B., Garcia, T., Benes, V., Leake, M.C., Linke, W.A. and Oberhauser, A.F. (2006). The molecular elasticity of the insect flight muscle proteins projectin and kettin. Proc. Natl. Acad. Sci. U S A 103, 4451-4456.

Qiu, F., Brendel, S., Cunha, P. F. M., Astola, N., Song, B., Furlong, E. E. M., Leonard, K.R. and Bullard, B. (2005). Myofilin, a protein in the thick filaments of insect muscle. J. Cell Sci. 118, 1527-1536.

Agianian, B., Krzic, U., Qiu, F., Linke, W. A., Leonard, K. and Bullard, B. (2004). A troponin switch that regulates muscle contraction by stretch instead of calcium. EMBO J. 23, 772-779.

Bullard, B., Ferguson, C., Minajeva, A., Leake, M.C., Gautel, M., Labeit, D., Ding, L., Labeit, S., Horwitz, J., Leonard, K.R. and Linke, W.A. (2004). Association of the chaperone alphaB-crystallin with titin in heart muscle. J. Biol. Chem. 279, 7917-7924.