Giulio Cossu - Publications#

Selected publications

Major publications

Fuoco C, Rizzi R, Biondo A, Longa E, Mascaro A, Shapira-Schweitzer K, Kossovar O, Benedetti S, Salvatori ML, Santoleri S, Testa S, Bernardini S, Bottinelli R, Bearzi C, Cannata SM, Seliktar D, Cossu G, Gargioli C. 2015. In vivo generation of a mature and functional artificial skeletal muscle. EMBO Mol Med. In press.

Bonfanti C, Rossi G, Tedesco FS, Giannotta M, Benedetti S, Tonlorenzi R, Antonini S, Marazzi G, Dejana E, Sassoon D, Cossu G, Messina G. 2015. PW1/Peg3 expression regulates key properties determining mesoangioblast stem cell competence. Nature Comm. In press.

Di Foggia V, Zhang X, Licastro D, Gerli M, Padkhe R, Muntoni F, Mourikis P, Tajbakhsk S, Ellis M, Greaves L, Taylor R, Cossu G, Robson L, Marino S. 2014. Bm1 enhances skeletal muscle regeneration through MT1 mediated oxidative stress protection in a mouse model of dystrophinopathy. J. Exp. Med. 211:2617-33.

Azzoni E, Conti V, Dellavalle A, Campana L, Adams RH, Cossu G, Brunelli S. 2014 Mouse yolk sac VE-Cadherin+ cells generate mesodermal multipotent progenitors that physiologically contribute to several lineages in the embryo and in the growing and regenerating skeletal muscle. Development 141:1821-34.

Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnanui MG, Messina G and Cossu G. 2013. Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Developmental Cell 24, 586-599.

Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G. 2012. Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy. Science Translational Medicine 4(140):140ra89.

Dellavalle A, Maroli G, Covarello D, Azzoni E, Innocenzi A, Perani L, Antonini S, Sambasivan R, Brunelli S, Tajbakhsh S and Cossu G. 2011. Pericytes resident in post-natal skeletal muscle differentiate into muscle fibers and generate satellite cells. Nature Comm. Oct 11;2:499.

Tedesco FS, Hoshiya H, D’Antona G, Gerli MFM, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M, Cossu G. 2011. Stem Cell-Mediated Transfer of a Human Artificial Chromosome Ameliorates Muscular Dystrophy. Science Translational Medicine 3:96ra78.

Messina G., Biressi S., Monteverde S., Magli A., Cassano M., Perani L., Roncaglia E., Tagliafico E., Starnes L, Cambpell CE., Grossi M., Goldhamer DJ., Gronostajski RM., Cossu G. (2010). Nfix regulates fetal specific transcription in developing skeletal muscle. Cell 140, 554-566. IF 31.152.

Gargioli C., Coletta M., De Grandis F., Cannata SM and Cossu G. (2008). PlGF-MMP9 expressing cells restore microcirculation and efficacy of cell therapy in old dystrophic muscle. Nature Med. 14:973-8. IF 27.136

Berghella L., De Angelis L., De Buysscher T., Mortazavi A., Biressi S., Forcales SV., Sirabella D., Cossu G. and Wold B. (2008). A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in post-natal muscle Genes & Dev. 22:2125-38. IF 12.075

Dellavalle A., Sampaolesi M., Tonlorenzi R., Tagliafico E., Sacchetti B., Perani L., Innocenzi B., Galvez BG., Messina G., Morosetti R., Li S., Belicchi M., Peretti G., Chamberlain JS., Wright WE, Torrente Y, Ferrari S, Bianco P and Cossu G. (2007). Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nature Cell Biol. 9:255-267. IF 19.527

Sampaolesi, M., Blot, S., D’Antona, G., Granger, N., Tonlorenzi, R., Innocenzi, A., Mognol, P., Thibaud, J.L., Galvez, B.G., Barthélémy, I., Perani, L., Mantero, S., Guttinger, M., Pansarasa, O., Rinaldi, C., Cusella De Angelis, M.G., Torrente, Y., Bordignon, C., Bottinelli, R. and Cossu, G. (2006). Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature, 444:574-9. IF 34.480

Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D’Antona G, Pellegrino MA, Barresi R, Bresolin N, Cusella De Angelis MG, Campbell KP, Bottinelli R, Cossu G. (2003) Cell therapy of alpha sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 301, 487-492. IF 29.747

Galli R, Borello U, Gritti A, Minasi MG, Bjornson C, Coletta M, Mora M, De Angelis MG, Fiocco R, Cossu G., Vescovi AL. (2000). Skeletal myogenic potential of human and mouse neural stem cells. Nature Neurosci. 3:986-91. IF 14.345

Ferrari G., Cusella-De Angelis G., Coletta M., Paolucci E., Stornaiuolo A., Cossu G., Mavilio F. (1998). Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279:1528-30. IF 29.747

Tajbakhsh S., Rocancourt D., Cossu G., Buckingham M. (1997). Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD. Cell 89:127-38. IF 31.152.

Tajbakhsh S., Vivarelli E., Cusella-De Angelis G., Rocancourt D., Buckingham M., Cossu G. (1994). A population of myogenic cells derived from the mouse neural tube. Neuron 13:813-21. IF 13.260