Yosef Gruenbaum - Selected Publications#

Zuela, N., Zwerger, M., Levin, T., Medalia, O. and Gruenbaum, Y. Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation. J. Cell Sci. 129:1781-1791 (2016).

Gruenbaum, Y. and Foisner, R. Lamins: Nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation. Annu. Rev. Biochem. 84:131-164 (2015).

Bar, D. Z., Charar, C., Dorfman, J., Yadid, T., Tafforeau, T., Lafontaine, D.L.J. and Gruenbaum, Y. Cell size and fat content of dietary restricted Caenorhabditis elegans are regulated by ATX-2, a novel mTOR repressor. Proc. Natl. Acad. Sci. USA. 113: E4620-4629.

Sharabi, K., Charar, C., Friedman, N., Mizrahi, I., Zaslaver, A., Sznajder, J.I. and Gruenbaum, Y. The response to high CO2 levels requires the neuropeptide secretion component HID-1 to promote pumping inhibition. PLoS Genet, 10: e1004529 (2014).

Zuela N., Bar, D.Z. and Gruenbaum, Y. Lamins in development, tissue maintenance and stress. EMBO Reports. 13, 1070-1078 (2012).

Mattout, A., Pike, B.L., Towbin, B.D., Bank, E.M., Meister, P., Gruenbaum**, Y. and Gasser*, S. A EDMD mutation in C elegans lamin that impairs muscle-specific gene relocation compromises muscle ultrastructure and head motility. Curr. Biol. 21, 1603-1614 (2011).

Penkner, A.M, Fridkin, A., Gloggnitzer, J., Baudrimont, A., Woglar, A., Csaszar, E., Pasierbek, P., Ammerer, G., Gruenbaum, Y. and Jantsch, V. Meiotic chromosome homology search involves changes in nuclear envelope properties in C. elegans. Cell 39, 920-933 (2009).

Sharabi, K. Hurwitz, A., Simon, A.J. Beitel, G.J., Morimoto, R.I., Rechavi, G., Sznajder, J.I. and Gruenbaum, Y. Elevated CO2 levels affects development, motility, fertility and extends lifespan in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 106, 4024-4029 (2009).

Wiesel, N., Mattout, A., Melcer, S., Melamed-Book, N., Herrmann, H., Medalia, O, Aebi, U. and Gruenbaum, Y. Laminopathic mutations interfere with the assembly, localization and dynamics of nuclear lamins. Proc. Natl. Acad. Sci. USA, 105, 180-185 (2008).

Margalit , A., Neufeld, E., Feinstein, N., Wilson, K.L., Podbilewicz, B. and Gruenbaum, Y. Barrier-to-autointegration factor (BAF) blocks premature cell fusion and maintains adult muscle integrity in C. elegans. J. Cell Biol. 178, 661-73 (2007),

Scopus citations > 10000, H-Index 54