Andrey Klymchenko - Biography#

Dr. Klymchenko is a CNRS Research Director of the 1st class (DR1) in the Laboratory of Bioimaging and Pathologies, UMR 7021 CNRS, University of Strasbourg and he is a head of the group Nanochemistry and Bioimaging.

Dr. Klymchenko obtained his PhD degree in chemistry from Kyiv National University in 2003. Then, he worked in the University of Strasbourg, where he could combine synthesis of new dyes with their bioimaging applications. In 2005, in order to extend his expertise towards supramolecular chemistry and nanotechnology, he moved to Catholic University of Leuven. Then, he joined CNRS in 2006, received CNRS Bronze Medal in 2010 and was promoted to Director of Research in 2014. In 2015, he obtained ERC consolidator grant BrightSens to work on fluorescent nanoparticles for ultrasensitive detection of cancer markers. In 2020, he research an ERC Proof-of-Concept, aimed to convert the developed ultrabright nanoparticles into tools for cancer diagnostics based on RNA analysis in cells. His research interests include functional fluorescent molecules and nanomaterials for biosensing, imaging and theranostics. He has developed a number fluorescent probes for cellular imaging, and many of them have been commercialized. His fluorescent probes have been used in hundreds of research laboratories worldwide. Moreover, he recently introduced new concepts for development of ultrabright dye-loaded nanoparticles based on polymers and lipids. These nanoprobes drastically enhance sensitivity of existing methods of biomolecular detection, offering new approaches in biosensing, bioimaging and molecular diagnostics. Based on his inventions, two start-up companies are planned to be created.