Wolfgang Löscher - Selected Publications#

1. Welzel, B. , Schmidt, R., Johne, M., and Löscher, W. (2023) Midazolam prevents the adverse outcome of neonatal asphyxia. Ann.Neurol. 93: 226-243.

2. Käufer, C., C. Chatbar, S. Bröer, I. Waltl, G. Luca, I. Gerhauser, U. Kalinke, and W. Löscher (2018). Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures. Proc.Natl.Acad.Sci.(USA), 115: E8929-E8938.

3. Noack, A., B. Gericke, M. von Köckritz-Blickwede, A. Menze, S. Noack, I. Gerhauser, F. Osten, H. Y. Naim, and W. Löscher (2018) A novel mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils. Proc.Natl.Acad.Sci.(USA), 115:E9590-E9599.

4. Töllner K, Brandt C, Töpfer M, Brunhofer G, Erker T, Gabriel M, Feit PW, Lindfors J, Kaila K, Löscher W (2014). A novel prodrug-based strategy to increase effects of bumetanide in epilepsy. Ann. Neurol. 75:550-562.

5. Löscher W, Klitgaard H, Twyman RE, Schmidt D (2013). New avenues for antiepileptic drug discovery and development. Nature Rev. Drug Discov. 12:757-776.

6. Brandt C, Nozadze M, Heuchert N, Rattka M, Löscher, W (2010). Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy. J. Neurosci. 30:8602-8612.

7. Volk HA, Löscher W (2005). Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures. Brain 128:1358-1368.

8. Löscher, W. and H. Potschka (2005) Drug resistance in brain diseases and the role of drug efflux transporters. Nature Rev. Neurosci., 6: 591-602.

9. Rogawski, M. A. and W. Löscher (2004) The neurobiology of antiepileptic drugs. Nature Rev. Neurosci., 5: 553-564.

10. Rogawski MA, Löscher W (2004). The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nature Med. 10:685-692.