Gemma Modinos - Publications#

Dr Modinos' work has made significant novel contributions to our understanding of the neuroanatomical, neurophysiological and neurochemical mechanisms involved in vulnerability for psychosis. She has built a strong reputation as an internationally recognised leader in translational neuroscience research in psychosis. Accordingly, her career has been characterised by extensive high-quality research outputs, published in the highest-ranking journals in psychiatry.

Total number of publications: 89 (of these, as first/senior author: 38).
Total number of citations (google scholar, extracted 22/04/2024): 5057; h-index (google scholar, extracted 22/04/2024): 35.

The 10 papers listed below represent a selection of Dr Modinos' major recent publications:

1. Livingston NR, Kiemes A, Devenyi GA, Knight, S, Lukow, PB, Jelen L, Reilly T, Dima A, Nettis MA, Casetta C, Agyekum T, Zelaya F, Spencer T, Fusar-Poli P, Grace AA, Williams SCR, McGuire P, Egerton A, Chakravarty MM, Modinos G. (2024). Effects of Diazepam on Hippocampal Blood Flow in people at Clinical High Risk for Psychosis. Neuropsychopharmacology (accepted/in press).

2. Kiemes A, Serrano Navacerrada ME, Kim E, Bernard C, Randall K, Simmons C, Gonzalez LR, Lythgoe D, Rotaru D, Vernon AC, Cash D, Modinos G. (2023). ErbB4 deletion from fast-spiking interneurons causes schizophrenia-relevant neuroimaging phenotypes. Schizophrenia Bulletin; 49(3):569-580.

3. Kirschner, M; Hodzic-Santor, B; Antoniades, A; Nenadic, I; Kircher, T; Krug, A; Meller, T; Grotegerd, D; Fornito, A; Arnatkeviciute, A; Bellgrove, MA; Tiego, J; Dannlowski, U; Koch, K; Hülsmann, C; Kugel, H; Enneking, V; Klug, M; Leehr, EJ; Böhnlein, J; Gruber, M; Mehler, D; DeRosse, P; Moyett, A; Baune, BT; Green, M; Quidé, Y; Pantelis, C; Chan, R; Wang, Y; Ettinger, U; Debbané, M; Derome, M; Gaser, C; Besteher, B; Diederen, K; Spencer, TJ; Fletcher, P; Rössler, W; Smigielski, L; Kumari, V; Premkumar, P; Park, HRP; Wiebels, K; Lemmers-Jansen, I; Gilleen, J; Allen, P; Kozhuharova, P; Marsman, JB; Lebedeva, I; Tomyshev, A; Mukhorina, A; Kaiser, S; Fett, AK; Sommer, I; Schuite-Koops, S; Paquola, C; Larivière, S; Bernhardt B; Dagher, A; Grant, P; van Erp, TGM; Turner, JA; Thompson, PM; Aleman, A; Modinos G. (2022). Cortical and Subcortical Neuroanatomical Signatures of Schizotypy in 3,004 Individuals Assessed in a Worldwide ENIGMA Study. Molecular Psychiatry; 27(2):1167-1176.

4. Kiemes A, Gomes FV, Cash D, Uliana DL, Simmons C, Singh N, Vernon AC, Turkheimer FE, Davies C, Stone JM, Grace AA, Modinos G. (2022). GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia. Neuropsychopharmacology; 47(3):687-695.

5. Lukow, PB, Martins D, Veronese M, Vernon AC, McGuire P, Turkheimer FE, Modinos G. (2022). Cellular and molecular signatures of in vivo GABAergic neurotransmission in the human brain. Communications Biology; 5(1):372.

6. Knight S, McCutcheon R, Dwir D, Grace AA, O’Daly O, McGuire P & Modinos G. (2022). Hippocampal circuit dysfunction in psychosis. Translational Psychiatry; 12(1):344

7. Modinos G, Kempton MJ, Tognin S, Calem M, Porffy L, Antoniades M, Mason A, Azis M, Allen P, Nelson B, McGorry P, Pantelis C, Riecher-Rössler A, Borgwardt S, Bressan R, Barrantes-Vidal N, Krebs MO, Nordentoft M, Glenthøj B, Ruhrmann S, Sachs G, Rutten B, van Os J, de Haan L, Velthorst E, van der Gaag M, Valmaggia LR, McGuire P; EU-GEI High Risk Study Group. (2020). Association of Adverse Outcomes With Emotion Processing and Its Neural Substrate in Individuals at Clinical High Risk for Psychosis. JAMA Psychiatry; 77(2):190-200.

8. Modinos G, Richter A, Egerton A, Bonoldi B, Azis M, Antoniades M, Bossong M, Crossley N, Perez J, Stone JM, Veronese M, Zelaya F, Grace AA, Howes OD, Allen P, McGuire P. (2021). Interactions between hippocampal perfusion and striatal dopamine function in people at clinical high risk for psychosis: relationship to clinical outcomes. Neuropsychopharmacology; 46(8):1468-1474

9. Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P. (2018). Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis. Neuropsychopharmacology; 43(13):2652-2659.

10. Modinos G, Allen P, Grace AA, McGuire P. (2015). Translating the MAM Model of Psychosis to Humans. Trends in Neurosciences. 38:129-38.