Bryan Paul Morgan - Selected Publications#

Over 320 published papers; H Index 67 (Web-of-Science).

1. Clark SJ, Briggs DC, White AM, Schmidt CQ, Hakobyan S, Morgan BP, Bishop PN. (2014) Identification of factor H-like protein 1 as the main complement regulator on the Bruch’s membrane: implications for age-related macular degeneration. J Immunol. 193: 4962-70 (20 cites).

2. Triantafilou K, Hughes TR, Triantafilou M, Morgan BP. (2013) The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. J Cell Sci; 126: 2903-13 (26 cites).

3. Goicoechea de Jorge E, Caesar JJ, Malik TH, Patel M, Colledge M, Johnson S, Hakobyan S, Morgan BP, Harris CL, Pickering MC, Lea SM. (2013) Dimerization of complement factor H-related proteins modulates complement activation in vivo. Proc Natl Acad Sci USA; 110(12): 4685-90 (24 cites).

4. Ramaglia V, Hughes TR, Donev RM, Ruseva MM, Wu X, Huitinga I, Baas F, Neal JW, Morgan BP. (2012) C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proc Natl Acad Sci USA; 109(3): 965-70 (31 cites).

5. Heurich M, Martinez-Barricarte R, Francis NJ, Roberts DL, Rodriguez de Córdoba S, Morgan BP, Harris CL. (2011) Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci USA; 108(21): 8761-6 (53 cites).

6. Ingram G, Hakobyan S, Hirst CL, Harris CL, Pickersgill TP, Cossburn MD, Loveless S, Robertson NP, Morgan BP. (2010) Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain; 133(Pt6):1602-11 (28 cites).

7. Martínez-Barricarte R, Heurich, M, Valdes-Cañedo F, Vazquez-Martul E, Torreira E, Montes T, Tortajada A, Pinto S, Lopez-Trascasa M, Morgan BP, Llorca O, Harris CL, Rodríguez de Córdoba S. (2010) Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides novel insights into complement activation and regulation. J Clin Invest; 120(10):3702-12 (73 cites).

8. Lewis RD, Jackson CL, Morgan BP, Hughes TR. (2010) The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice. Mol Immunol; 47(5):1098-105 (21 cites).

9. Meri S, Morgan BP, Davies A, Daniels RH, Olavesen MG, Waldmann H, Lachmann PJ. (1990) Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology; 71:1-9 (395 cites).

10. Piddlesden SJ, Lassmann H, Zimprich F, Morgan BP, Linington C. (1993) The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement. Am J Pathol; 143(2):555-64 (204 cites).