Valerie O'Donnell - Selected Publications#
Total publications 127, H-index 52 (Google Scholar).
1. Meckelmann, SW, Hawksworth, JI, White, D, Andrews, R, Rodrigues, P, O’Connor, A, Alvarez-Jarreta, J, Tyrrell, VJ, Hinz, C, Zhou, Y, Williams, J, Aldrovandi, M, Watkins, WJ, Engler, AJ, Lo Sardo, V, Slatter, DA, Allen, SM, Acharya, J, Mitchell, J, Cooper, J, Aoki, J, Kano, K, Humphries, SE, and O’Donnell, VB. (2020) Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274 Circulation: Genomics and Precision Medicine (https://doi.org/10.1161/CIRCGEN.119.002806
)2. Allen-Redpath, K, Aldrovandi, M, Lauder, S, Gketsopoulou, A. Tyrrell, VJ, Slatter, DA, Andrews, R, Watkins, WJ, Atkinson, G, McNeill, E, Gilfedder, A, Protty, M, Burston, J, Johnson, SRC, Rodrigues, PRS, Jones, DO, Lee, R, Handa, A, Channon, K, Obaji, S, Alvarez-Jarreta, J, Krönke, G, Ackermann, J, Jenkins, PV, Collins, PW and O’Donnell, VB. (2019) Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity. Proc Natl Acad Sci, USA 116 (16) 8038-8047 https://doi.org/10.1073/pnas.1814409116
(Impact factor 9.8, cited 10 times) 3. Fahy, E, Alvarez-Jarreta,J, Brasher, CJ and O’Donnell, VB (2018) LipidFinder on LIPID MAPS: peak filtering, MS searching and statistical analysis for lipidomics. Bioinformatics bty679, https://doi.org/10.1093/bioinformatics/bty679
, 15. 4. O’Donnell, VB, Rossjohn, J, Wakelam, MJO (2018) Phospholipid signalling in innate immune cells. J Clin Invest 128(7):2670-2679 https://doi.org/10.1172/JCI97944.
5. Lauder, SN, Allen-Redpath, K, Slatter, DA, Aldrovandi, M, O’Connor, A, Farewell, D, Percy, CL, Molhoek, JE, Rannikko, S, Tyrrell, VJ, Ferla, S, Milne, GL, Poole, AW, Thomas, CP, Obaji, S., Taylor, PR, Jones, SA, de Groot, PG, Urbanus, RT, Horkko S, Uderhardt, S, Ackermann, J, Jenkins, PV, Brancale, A, Krönke, G, Collins, PW and O’Donnell, VB (2017) Networks of enzymatically oxidized membrane lipids support calcium - dependent coagulation factor binding to maintain hemostasis. Science Signaling Vol. 10, Issue 507, eaan2787, DOI: 10.1126/scisignal.aan2787
6. Lue, H, Podolak, J, Kolahi, K, Cheng, L, Soumya, R, Garg, D, Xue, C, Rantala, J, Tyner, J, Thornburg, K, Martinez-Acevedo, A, Liu, J, Amling, C, Truillet, C, Evans, M, O’Donnell, VB, Nomura, D, Drake, J, Ritz, Anna, Thomas, G. (2017) Treatment-induced autophagy sustains residual disease in cancers through phospholipase A2 Genes and Development 31: 2067-2084 doi: 10.1101/gad.305292.117
7. Slatter, DA, Percy, CL, Allen-Redpath, K, Gajsiewicz, J, Brooks, NJ, Clayton, A, Tyrrell, VJ, Lauder, SN, Watson, A, Dul, M, Garcia-Diaz, Y, Aldrovandi, M, Heurich, M, Hall, J, Morrissey, JH, Lacroix-Desmazes, S, Delignat, S, Jenkins, PV, Collins, PW and O’Donnell, VB (2018) Enzymatically-oxidized phospholipids restore blood clot formation in factor VIII deficiency through supporting factor activities on membrane surfaces J Clin Invest Insight 3(6):e98459. https://doi.org/10.1172/jci.insight.98459
8. Uderhardt, S, Ackermann, J, Fillep, T, Hammond, VJ, Willeit, J, Santer, J, May, M, Biburge, M, Miller, M, Zellner, K, Stark, K, Zarbock, J, Rossaint, A, Schubert, I, Mielenz, D, Dietel, B, Raaz-Schrauder, D, Ay, C, Gremmel, T, Thaler, J, Heim, C, Herrmann, M, Collins, PW, Schabbauer, G, Mackman, N, Voehringer, D, Nadler, JL, Lee, JJ, Massberg, S, Rauh, M, Kiechl, S, Schett, G, O’Donnell, VB, Krönke, G. (2017) Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis and thrombotic disease J Exp Med 214(7):2121-2138. doi: 10.1084/jem.20161070
9. Slatter, DA, Aldrovandi, M, O’Connor, A, Allen, S, Brasher, C, Murphy, RC, Meckelmann, S, Ravi, S, Darley-Usmar, V and O’Donnell, VB. (2016) Mapping the human platelet lipidome reveals cytosolic phospholipase A2 as a regulator of mitochondrial bioenergetics during activation. Cell Metabolism 23, 930-934, with commentary by FitzGerald, GA, Human platelet lipidomics: variance, visualization, flux and fuel. 23, 757-759
10. Hinz, C, Aldrovandi, M, Uhlson, C, Podmore, H, Hornshaw, M, Marnett, LJ, Longhurst, HJ, Warner, TD, Alam, S, Slatter, DA, Lauder, SN, Allen-Redpath, K, Collins, PW, Murphy, RC, Thomas, CP and O’Donnell, VB. (2016) Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. J Biol Chem 291(26):13448-64. doi: 10.1074/jbc.M115.700609.
