Karin Rose Sipido #

Selected research publications

Dries E, Santiago DJ, Johnson DM, Gilbert G, Holemans P, Korte SM, Roderick HL, Sipido KR. (2016) Calcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during β-adrenergic stimulation is restricted to the dyadic cleft. J Physiol 594(20):5923-5939

Macquaide N, Tuan HT, Hotta J, Sempels W, Lenaerts I, Holemans P, Hofkens J, Jafri MS, Willems R, Sipido KR. (2015) Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release. Cardiovasc Res 108(3):387-98

Dries E, Bito V, Lenaerts I, Antoons G, Sipido KR, Macquaide N. (2013) Selective modulation of coupled ryanodine receptors during microdomain activation of calcium/calmodulin-dependent kinase II in the dyadic cleft. Circ Res 113(11):1242-52

Kararigas G, Bito V, Tinel H, Becher E, Baczko I, Knosalla C, Albrecht-Küpper B, Sipido KR, Regitz-Zagrosek V. Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function. J Am Coll Cardiol. 2012 Jan 24;59(4):410-7

Heinzel FR, Bito V, Biesmans L, Wu M, Detre E, von Wegner F, Claus P, Dymarkowski S, Maes F, Bogaert J, Rademakers F, D'hooge J, Sipido K. (2008) Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium. Circ Res 102(3):338-46

Louch, W.E., Bito, V, Heinzel, F R, Macianskiene, R, Vanhaecke, J, Flameng, W, Mubagwa, K, Sipido, K R. (2004).
Reduced synchrony of Ca2+ release with loss of T-tubules - a comparison to human failing cardiac myocytes. Cardiovasc Res 62: 63-73.


Policy and policy research papers

Landray MJ, Bax JJ, Alliot L, Buyse M, Cohen A, Collins R, Hindricks G, James SK, Lane S, Maggioni AP, Meeker-O'Connell A, Olsson G, Pocock SJ, Rawlins M, Sellors J, Shinagawa K, Sipido KR, Smeeth L, Stephens R, Stewart MW, Stough WG, Sweeney F, Van de Werf F, Woods K, Casadei B. Improving public health by improving clinical trial guidelines and their application. Eur Heart J. 2017 Mar 8. doi: 10.1093/eurheartj/ehx086. Epub ahead of print

Gal D, Glänzel W, Sipido KR. Mapping cross-border collaboration and communication in cardiovascular research from 1992 to 2012. Eur Heart J. 2016 Oct 25. doi: 10.1093/eurheartj/ehw459.

Sipido K, Degos L, Frackowiak R, Ganten D, Hofstraat H, Horvath I, Luyten F, Manns M, Oertel W, Zima T. Scientific Panel for Health: better research for better health. Lancet. 2016 Aug 27;388(10047):865-6

Kirchhof P, Sipido KR, Cowie MR, Eschenhagen T, Fox KA, Katus H, Schroeder S, Schunkert H, Priori S; ESC CRT R&D and European Affairs Work Shop on Personalized Medicine. The continuum of personalized cardiovascular medicine: a position paper of the European Society of Cardiology. Eur Heart J. 2014 Dec 7;35(46):3250-7