Gregory Stephanopoulos - Selected Publications#

1. G. Stephanopoulos, J. Nielsen, and A. Aristidou, Metabolic Engineering. Principles & Methodologies, Academic Press (1998).

2. S. Y. Lee, J. Nielsen and G. Stephanopoulos, (series editors), Advanced Biotechnology, Wiley, VCH, Weinheim, Germany (2021).

3. S. Y. Lee, J. Nielsen and G. Stephanopoulos, (editors), Metabolic Engineering, Concepts and Applications, Volumes 13 a and b in the series Advanced Biotechnology, S.Y. Lee, J. Nielsen and G. Stephanopoulos (editors), Wiley, VCH, Weinheim, Germany (2021).

4. J.O. Park, N. Liu, K.M. Holinski, D.F. Emerson, K.J. Qiao, B.M Woolston, J. Wu, Z. Lazar, M.A. Islam, C. Vidoudez, P.R. Girguis and G. Stephanopoulos, “Synergistic substrate co-feeding stimulates reductive metabolism,” Nature Metabolism, 1(6): 643–651; DOI: 10.1038/s42255-019-0077-0 (2019).

5. Li, Jingbo, Y. Ma, N. Liu, B. E. Eser, Z. Guo, P. R. Jensen, and G. Stephanopoulos. “Synthesis of High-Titer Alka(e)Nes in Yarrowia lipolytica Is Enabled by a Discovered Mechanism.” Nature Communications, 11(1): 1-13.DOI: 10.1038/s41467-020-19995-0 (2020).

Selected for Editors’ Highlights: www.nature.com/collections/idhhgedgigand

6. F. Lam, G. Fink and G. Stephanopoulos, “Engineered tolerance in yeast enables efficient production from toxic hydrolysates of lignocellulosic biomass,” Science Advances, (7, Issue 26, (2021), doi.org/10.1126/sciadv.abf7613.

7. B.W. Biggs, H.S. Alper, B.F. Pfleger, K.E.J. Tyo, C.N.S. Santos, P.K. Ajikumar*, G. Stephanopoulos* , “Enabling commercial success of industrial biotechnology,” Science. 374: 1563-1565 (2021).

8. C.M. Metallo, P.A. Gameiro, E.L. Bell, K. Hiller, Z.R. Johnson, L. Guarente, J.K. Kelleher, M.G. Vander Heiden, O. Iliopoulos and G. Stephanopoulos, “Reductive metabolism by IDH1 mediates lipogenesis of tumor cells under hypoxia,” Nature, 481: 380-384 (2012). Selected for Faculty of 1000 Biology, which highlights and evaluates the most interesting papers published in the biological sciences, based on the recommendations of over 2000 of the world's top researchers.

9. P. K. Ajikumar, W.-H. Xiao, K. E. J. Tyo, Y. Wang, E. Leonard, O. Mucha, H. P. Too, B. Pfiefer and G. Stephanopoulos, “Isoprenoid pathway optimization by a multivariate-modular approach for Taxol precursor overproduction in Escherichia coli,” Science, 330: 70-74 (2010).

10. G. Stephanopoulos, “Challenges in engineering microbes for biofuels production,” Science, 315: 801-804, (2007).