Richard Charles Trembath - Curriculum Vitae#

Richard Charles Peter TREMBATH, BSc, MBBS, FRCP, F.MedSci
Executive Dean of Faculty of Life Sciences & Medicine, King’s College London
Professor of Medical Genetics, Division of Genetics and Molecular Medicine
Honorary Consultant in Clinical Genetics, Guy’s and St Thomas’. NHS Foundation Trust

ACADEMIC CONTRIBUTIONS

His research interests include the identification and characterisation of genes and the molecular pathways underlying a range of human common and rare disorders.

He is distinguished for his contributions to medical molecular genetic research, in a wide-ranging programme aimed at delineating the molecular genetic basis of single gene and common complex disorders. With Anita Harding, he was the first to show that mutations in mitochondrial DNA can predispose to diabetes mellitus.

Recent major contributions include the positional cloning of genes involved in the most common syndromic form of hearing loss, Pendred syndrome; the identification of the gene mutated in partial lipodystophy, an adipocyte disorder.

Working with colleagues at the University of Cambridge and the Wellcome Trust Sanger Institute, He is the Principal investigator and Co-Director of a major population genomics programme, known as East London Genes and Health (http://www.genesandhealth.org).

With Anita Harding, he demonstrated that mutations in mitochondrial DNA lead to β-cell dysfunction and diabetes mellitus. His group discovered human TGF-beta receptor genes that drive pulmonary arterial hypertension, partial lipodystrophy, disorders of development including sensori-neural hearing loss and identified the genetic landscape of common skin inflammation.

He has supervised through to PhD defense, a total of 20 graduate students.

ACADEMIC LEADERSHIP

Professor of Medical Genetics and clinician scientist (clinically active)

Present; Executive Dean, Faculty of Life Science and Medicine, King’s College London,
Past; Vice-Principal for Health, Queen Mary University of London (2011-15), former NIHR Senior Investigator and NIHR GSTT/KCL Comprehensive Biomedical Research Centre Director (2007-2011), Board Executive, UK BioCentre (NIHR National Bio-sample Centre), Board of the Hefce Catalyst Centre for Precision Medicine, former non-executive director of Bart’s Health NHS Trust and present non-executive director of King’s College NHS Foundation Trust.

He has more than 25 years’ experience across the breadth of medical and molecular genetics, past President of the British Society of Human Genetics (2005-7). H-Index of 81, reflecting research that has been supported through programme support from the Medical Research Council (MRC), British Heart Foundation and the Wellcome Trust, (WT). His commitment to training is underpinned through terms as Deputy Chair and member respectively of the WT and MRC Clinical Training panels. Elected to the Fellowship of the Academy of Medical Sciences in 2003.